[PDF] Top 20 Mobile genetic elements and genome evolution 2014

... Kevin Gunderson (Illumina, USA) described how trans- posase biochemistry is being used to streamline library preparation for high throughput sequencing and to create novel sequencing libraries supporting synthetic long ... See full document

... A variety of cellular proteins have binding sites in the reg- ulatory region of polyomavirus genomes (25). Most of these sites are located in a segment first identified as an enhancer of the early promoter (10). Later, ... See full document

... transposable elements in eukaryotes, models that consider factors such as mutation, recombination and drift have successfully predicted the number of transposable element copies within a genome [63, 72], ... See full document

... Six other CDSs with homologies to other drug resis- tance genes were identified in the L. hongkongensis gen- ome (Table 4). A putative dimethyladenosine transferase, encoded by ksgA gene (LHK_00025) was found. ... See full document

... al 2014) and worldwide (Carattoli, 2009, Shahid et ...the evolution and transmission of resistance to the β-lactam antibiotics among the Enterobacteriaceae in both community and hospital ...of ... See full document

... the genome assem- bly (note, that MGE type should be specified according to names of the records in the FASTA file which might be checked using ‘--check-types’ ... See full document

... characterize genome sequences of scarce samples or even single ...L1Hs elements are population-specific [46,47], and recapitulate genetic ancestry similar to Alu insertion polymorphisms ... See full document

... phages and plasmids, suggesting CRISPR interference against these mobile elements, which was later experimentally confirmed in the R20291 strain (ST1/RT027/B1) (3, 43). Recently, in a comprehensive analysis ... See full document

... Transposable elements (TEs) are a major component of most eukaryotic ...II elements are DNA transposons that adopt a ‘cut-and-paste’ approach catalyzed by enzymes called ...The elements of this class ... See full document

... A total of 837 strains were prospectively and consecu- tively collected from 2011 to 2014 at Nanfang Hospital, a large tertiary-level teaching hospital with 2,200 beds in Guangzhou, southern China. The patients in ... See full document

... eukaryotic genome organization, the exon–intron gene ...population- genetic perspective provides concrete indications that this is what they ...eukaryotic evolution, they invaded the genomes as ... See full document

... However, genetic mechanisms and genomic targets of domestication are still poorly ...The genetic signatures of domestication are revealed by comparison of different mammalian species and ...cattle ... See full document

... For the comparison of distances separating neighbor genes, homeologous triplets located in the three chromosomal compartments (distal, interstitial, and proximal; Add- itional file 1: Table S2) were treated separately. ... See full document

... of mobile pro- moters in prokaryotic ...of mobile promoters, ...of genome, and hence is able to reveal differences in the dynamics in these two ...to mobile genetic elements in ... See full document

... Josh Dubnau (Stony Brook University, USA) described TDP-43, an RNA and DNA binding protein that forms cytoplasmic inclusions in the vast majority of both fa- milial and sporadic cases of amyotrophic lateral sclerosis ... See full document

... Mobile genetic elements are common inhabitants of virtually every genome where they can exert profound influences on genome structure and function in addition to promoting their own ... See full document

... regulatory elements to gene regions; a concept that was initially posed by Britten and Davidson [37] and which was recently reviewed comprehensively in Chuong, Elde, and Feschotte ...binding elements that ... See full document

... cancer genome (29, ...HPV genome, the six patterns of substitution were further classified into 96 base substitution types within the trinucleotide context of the bases immediately 5= and 3= to each ... See full document

... This study provides one of the first combinations of phenotypic analyses that span multiple cell types, alongside full comparative genomic analyses that span both phylogenetic and gene-specific analyses. One comparison not ... See full document

... Our detailed comparison of the PFGE patterns and the accessory genomes showed that different PFGE patterns reflected myriad changes in mobile elements of the accessory genome, particularly ... See full document