[PDF] Top 20 Model for Vesicular Stomatitis Virus

... 10, 1972 MODEL FOR VESICULAR STOMATITIS VIRUS tures for the tubular portion: i a matrix protein layer based on an icosahedron cut across the twofold axis with the surface projection laye[r] ... See full document

... Crystallization and structure determination. Crystallization of VSV NLP has been previously reported (10). Purified N protein devoid of RNA and N protein with encapsidated poly-RNA (A, C, G, or U) were crystallized by ... See full document

... While the VSV-G protein clearly binds to PS, as demon- strated by others, this interaction does not appear to be rele- vant for VSV binding to cells, suggesting the presence of an undetermined cell surface receptor. ... See full document

... In considering hybrid proteins as subunit vaccines, one should stress the importance of aligning T-helper epitopes because of their often critical roles in enhancement and tar- geting of the immune response for ... See full document

... Vesicular stomatitis virus replicates normally in enucleate cells with the rate of production of infectious virus, the amount of virus-specific protein synthesis, and the type of protein[r] ... See full document

... The results show that the type C dynamics, which allows a continuous competition among a large number of transferred viral genomes, can permit populations to reach fitness [r] ... See full document

... The main limitation of this study is the host’s immune response. Every individual could respond to the introduction of VSV differently, despite the results concluded in the study. If an individual’s innate immune system ... See full document

... on vesicular stomatitis virus (VSV) infection were investigated by using a VSV-susceptible mouse neuroblastoma cell line, ...of virus tested (MOIs of ... See full document

... When the synthetic NJ77 nucleocapsids encapsidated in the specific reaction were incubated with the VSVNJ RNA polymerase, we detected an RNA product about the length of the nucleocapsid [r] ... See full document

... To test this hypothesis, we performed a rescue assay by coexpressing QN-1 and the wild-type G protein of the New Jersey serotype GNJ- We have shown previously that GNJ is efficiently inc[r] ... See full document

... Second, we cloned cDNA copies of the entire coding region for M protein of wild-type virus and of a ts mutant into a simian virus 40 SV40 expression vector and compared the CPE in transf[r] ... See full document

... NS protein from the cytoplasmic fraction of infected cells after labeling with [35S]methionine A or 32p B or from in vitro synthesis with [N-formyl-35S]methionine C was purified on SDS-P[r] ... See full document

... Since the synthetic peptide KFT25 exhibits hemolytic properties similar to those of VSV and G protein 14, it was speculated that the amino terminus of G protein represents an important d[r] ... See full document

... Inhibition of mouse L cell protein synthesis by ultraviolet-irradiated vesicular stomatitis virus requires viral transcription.. Differential inhibition of host protein synthesis in L ce[r] ... See full document

... However, it should be noted that no such differences in radioactive labeling of the M protein could be observed with 248 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest[r] ... See full document

... Examination of these replicative complexes by electron microscopy revealed several morphological characteristics: i all RNPs observed were coiled structures with mean dimensions of 20 by[r] ... See full document

... 13 showed that the only 20 Downloaded from http://jvi.asm.org/ on November 11, 2019 by guest The antigens of the nucleoprotein core and the coat of vesicular stomatitis virus VSV particl[r] ... See full document

... Multiple TRIM69 alleles circulate in human populations, and TRIM69 exhibits strong signatures of positive selection. We next analyzed structural variation at the TRIM69 locus in human populations, using data from the ... See full document

... Proteins of Vesicular Stomatitis Virus and of Phenotypically Mixed Vesicular Stomatitis Virus-Simian Virus 5 Virions' Received for publication 11 August 1971 The identity of the glycopro[r] ... See full document

... Extending our conclusion that shutoff is due to mRNA competition, we show further that the average size of polysomes translating viral and cellular nmRNA was threefold smaller in cells i[r] ... See full document