[PDF] Top 20 Mouse Model for the Equilibration Interaction between the Host Immune System and Human T-Cell Leukemia Virus Type 1 Gene Expression
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Mouse Model for the Equilibration Interaction between the Host Immune System and Human T-Cell Leukemia Virus Type 1 Gene Expression
... lanes 1 to 4), while the amount of Gax protein in EL4/Gax cells that had been cultured in vitro without a drug remained un- changed for the same period as in the case of in vivo inocula- tion (lane ...Gax ... See full document
11
Broad host range of human T-cell leukemia virus type 1 demonstrated with an improved pseudotyping system.
... of gene transcription (10, 44), and induction of cellular differentiation ...the expression of other viral ...cocultivation system. Improved HTLV-1 titers were also obtained with ... See full document
5
Transmission of Human T-Cell Leukemia Virus Type 1 to Mice
... from mouse 33, indicates effi- cient replication and infection in mouse ...of mouse 51, was consistent with the possibility that this virus replicates mainly by cell division rather ... See full document
6
Silencing of human T cell leukemia virus type I gene transcription by epigenetic mechanisms
... Human T-cell leukemia virus type I (HTLV-I) is associated with a neoplastic disease, adult T-cell leukemia (ATL), and inflammatory diseases, such as ... See full document
16
Activation of Human T-Cell Leukemia Virus Type 1tax Gene Expression in Chronically Infected T Cells
... other host and viral factors also play a ...appearance, host factors such as the immune response as well as the intracellular regulation of viral gene expression may be ...that ... See full document
7
Analysis of p53 Inactivation in a Human T-Cell Leukemia Virus Type 1 Tax Transgenic Mouse Model
... transgenic mouse model to determine the contribution of p53 inactivation to Tax-induced ...vivo mouse model of tumorigenesis does not affect the transactivation function of p53 and that p53 ... See full document
9
The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes.
... HTLV-induced T-cell transformation re- mains unknown. Patients with HTLV-1 infection who develop adult T-cell leukemia do so after a 25- to 30-year latent ...Tax ... See full document
9
Kinetic Analysis of Human T-Cell Leukemia Virus Type 1 Gene Expression in Cell Culture and Infected Animals
... viral gene expression profile throughout the immortalization process and the relationships of individual gene expression to infected cell survival and cellular transformation have not ... See full document
10
Stromal Cell-Mediated Suppression of Human T-Cell Leukemia Virus Type 1 Expression In Vitro and In Vivo by Type I Interferon
... Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL), HTLV-1-associated myelopathy/tropical spastic ... See full document
8
Role of O-Glycosylation and Expression of CD43 and CD45 on the Surfaces of Effector T Cells in Human T Cell Leukemia Virus Type 1 Cell-to-Cell Infection
... in 1 ml of ice-cold lysis buffer containing 1% Triton X-100 (Sigma), 150 mM NaCl, 10 mM Tris (pH ...After 1 h of extraction at 4°C, insoluble material was removed by centrifugation at 14,000 ⫻ g for ... See full document
12
Transcriptional activation of the vascular cell adhesion molecule-1 gene in T lymphocytes expressing human T-cell leukemia virus type 1 Tax protein.
... of T cells through the blood-brain barrier are favored by adhesion molecule- mediated interactions of circulating T cells with endothelial ...in human T-cell leukemia ... See full document
9
Human T cell leukemia virus type I Tax induces the expression of CD83 on T cells
... Human T-cell leukemia virus type-I (HTLV-I) is a human retrovirus that is etiologically associated with adult T-cell leukemia (ATL) [16] and ... See full document
13
Human T-Cell Leukemia Virus Type 1 Tax Shuttles between Functionally Discrete Subcellular Targets
... A subpopulation of Tax in TSS colocalizes with sites of transcription. Tax predominately localizes to the nucleus of cells, displays a speckled pattern, and is excluded from the nucleolus (41, 42). We previously noted ... See full document
14
Altered Expression of Tyrosine Kinases of the Src and Syk Families in Human T-Cell Leukemia Virus Type 1-Infected T-Cell Lines
... fynB expression in most HTLV- 1-infected cell ...fyn gene in C91 cells could explain the high intrinsic activity of Fyn in this cell ...fynT/fynB expression in C91 by ... See full document
9
Intracellular Distribution of Human T-Cell Leukemia Virus Type 1 Gag Proteins Is Independent of Interaction with Intracellular Membranes
... fixing and quenching and the anti-Gag ascitic fluid was used simultaneously with rabbit sera directed to cellular compart- ments; labeled structures were then revealed by FITC-coupled goat anti-mouse ... See full document
7
The Role of WWP1-Gag Interaction and Gag Ubiquitination in Assembly and Release of Human T-Cell Leukemia Virus Type 1
... of virus particle ...transfection, cell extracts and pelleted supernatants were prepared and equivalent amounts of each sample were fractionated by sodium dodecyl sulfate- polyacrylamide gel ...in ... See full document
9
Highly Enhanced Expression of CD70 on Human T-Lymphotropic Virus Type 1-Carrying T-Cell Lines and Adult T-Cell Leukemia Cells
... amine gene expression patterns of PBMCs infected with HTLV-1 (11), HTLV-1-transformed T-cell lines (8, 30), Jurkat cells expressing either p12I (26) or p30II (23), and the Jurkat ... See full document
10
The role of chromatin in the transcriptional regulation of the human T-cell leukemia virus type 1
... XVll ER estrogen receptor ESAI essential SAS2-related acetyltransferase Exoill Exonuclease III g relative centrifugal force GM-CSF Granulocyte macrophage-colony stimulating factor GR glu[r] ... See full document
268
Phosphorylation regulates human T cell leukemia virus type 1 Rex function
... in cell growth, cell cycle control, DNA repair, and cell differentiation ...controlling expression of the structural and enzymatic proteins that are essential for production of viral progeny ... See full document
11
Oral Administration of Human T-Cell Leukemia Virus Type 1 Induces Immune Unresponsiveness with Persistent Infection in Adult Rats
... cellular immune responses to HTLV-1 varies and weak cellular im- mune responses are known to be associated with lymphopro- liferative ...for immune unresponsiveness against HTLV-1 not only in ... See full document
5
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