[PDF] Top 20 A negative regulation loop of long noncoding RNA HOTAIR and p53 in non-small-cell lung cancer
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A negative regulation loop of long noncoding RNA HOTAIR and p53 in non-small-cell lung cancer
... the negative correlation between p53 and HOTAIR was known, we next studied possible interaction between these two molecules via bioinformatics ...two p53 binding sites were found on the ... See full document
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Original Article Up-regulation of long non-coding RNA HOXA-AS2 in non-small cell lung cancer is associated with worse survival outcome
... Background: Long non-coding RNAs (lncRNAs) are noncoding RNAs that regulate cellular processes during the progression of ...human non-small cell lung cancer ... See full document
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<p>Long Noncoding RNA H19 Facilitates Small Cell Lung Cancer Tumorigenesis Through miR-140-5p/FGF9 Axis</p>
... Figure 3 H19 directly bound and negative regulated expression of miR-140-5p. (A) A schematic outline of sequence sites of miR-140-5p targeted to H19 was predicted by bioinformatic analysis. (B) miR-140-5p ... See full document
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Original Article A novel long noncoding RNA IRAIN regulates cell proliferation in non small cell lung cancer
... the regulation of gene expres- sion, involved in tumorigenesis and other bio- logical progression ...of HOTAIR has been noted in various primary and meta- static tumors, including breast, liver and the ... See full document
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Original Article Long noncoding RNA ZEB1-AS1 predicts an unfavorable prognosis of non-small lung cancer and regulates epithelial to mesenchymal transition through reducing ZEB1 expression
... Abstract: Long non-coding RNAs (lncRNAs) are critical gene regulators with important roles in a wide variety of bio- logical processes, including ...and cell lines, and its expression levels were ... See full document
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Long noncoding RNA ANRIL could be transactivated by c-Myc and promote tumor progression of non-small-cell lung cancer
... of the construct, while inhibition of c-Myc suppressed the luciferase activity of the construct (Figure 3A and B). To further confirm the specificity of the interaction, we synthe- sized the E-box element with point ... See full document
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Original Article Long noncoding RNA PVT-1 predicts poor patient prognosis in non-small cell lung cancer
... Traditionally, cancer was regarded as a genetic disease, but current research revealed that cancer devel- opment and progression involves epi- genetic abnormalities ...epigenetic regulation such as ... See full document
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Diagnostic significance of circulating long noncoding RNA PCAT6 in patients with non-small cell lung cancer
... tests for the diagnosis of early stage NSCLC is clinically important, as blood samples are easily acquired in a relatively noninvasive manner compared with biopsy or surgery. The most widely used serum biomarkers of ... See full document
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Original Article Long noncoding RNA CCAT2 promotes proliferation and metastasis in non-small cell lung cancer through the Wnt pathway
... epithelial lung cancer other than small cell lung carcinoma (SCLC) [17, ...to small cell ...of non-coding RNAs, including small RNAs (miRNA) and long ... See full document
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Long noncoding RNA PXN-AS1-L promotes non-small cell lung cancer progression via regulating PXN
... of lung cancer metasta- sis ...NSCLC cell proliferation ...inhibit cell survival ...promote cell migration [35]. LncRNA LINC00473 is reported to promote lung cancer tumor ... See full document
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Original Article Long noncoding RNA TINCR promoted cell proliferation through sponging miR-29b in non-small cell lung cancer
... in regulation of can- cer cells phenotypes by regulating target gene expression by different mechanisms, including chromatin modification, genomic imprinting, RNA decay and sponging ...colorectal ... See full document
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Functions and mechanisms of long noncoding RNAs in lung cancer
... MALAT1, HOTAIR, HNF1A-AS1, ANRIL, and PVT1 is associated positively with lymph node metastases, whereas the expression of SPRY4-IT1 and BANCR is negatively corre- ...a negative prognostic marker for patient ... See full document
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An overview of long non-coding RNAs in ovarian cancers
... induce p53 as well as to inhibit cell proliferation in the absence of p53 underlines its tumor suppressor activity ...ovarian cancer tissues and cell ...OVCAR3 cell line growth ... See full document
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Polymorphism in lncRNA AC016683.6 and its interaction with smoking exposure on the susceptibility of lung cancer
... in a similar dose-dependent manner. The odds ratios (ORs) and their 95% confidence intervals (CIs) were used to evaluate the relationships between rs4848320, rs1110839 genotypes and lung cancer risk by ... See full document
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<p>Association Between lncRNA HULC rs7763881 Polymorphism and Gastric Cancer Risk</p>
... metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) 13,14 have been reported as oncogenes that are upregulated in gastric ...gastric cancer. The lncRNA highly upregulated liver cancer ... See full document
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Integrated TCGA analysis implicates lncRNA CTB-193M12.5 as a prognostic factor in lung adenocarcinoma
... the RNA sequencing technology has greatly facilitated identifying lncRNAs associated with various ...contrast, RNA-Seq enjoys a number of advantages, including very low background signal and large dynamic ... See full document
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Evaluation of long noncoding RNA MALAT1 as a candidate blood based biomarker for the diagnosis of non small cell lung cancer
... between cancer patients and cancer-free ...from cancer-free controls a sensitivity of 56% was calculated conditional on a high specificity of ... See full document
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The lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer
... confirmed lung cancer without radio- or ...any cancer were recruited from the same hospital during the same time, based on frequency matched to cases by gender and age ( ± 5 ... See full document
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Overall survival of driver mutation-negative non-small cell lung cancer patients with COPD under chemotherapy compared to non-COPD non-small cell lung cancer patients
... Only variables that were statistically significant in uni- variate analysis were entered into the multivariate analysis. Both univariate and multivariate analyses of overall survival are performed using Cox regression ... See full document
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HUWE1 controls the development of non-small cell lung cancer through down-regulation of p53
... the RNA-Seq data of lung adenocarcinoma and squamous cancer tissues from TCGA, we found that the expression of CDKN1A (the gene encoding p21) in the HUWE1-low expression group was significantly ... See full document
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