[PDF] Top 20 Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins.
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Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins.
... Four separate regions of homology were identified within the N-terminal 180 amino acids of NS3; three encompassed the catalytic 2467 Downloaded from http://jvi.asm.org/ on November 10, 2[r] ... See full document
9
Modulation of Hepatitis C Virus NS5A Hyperphosphorylation by Nonstructural Proteins NS3, NS4A, and NS4B
... C virus (HCV) is a highly phosphorylated protein involved in resistance against interferon and required most likely for replication of the viral ...multiple proteins with different electrophoretic ... See full document
9
Cleavage Map and Proteolytic Processing of the Murine Norovirus Nonstructural Polyprotein in Infected Cells
... that required cellular factors, because in vitro processing of Nterm in TNT reactions had not been detected in this study or other studies (15, 25, ...region proteins of other caliciviruses, ... See full document
16
Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins.
... In flavivirus, NS3 is necessary, but not sufficient, for processing at the nonstructural cleavage sites: in addition to the catalytic NS3 domain, NS2B is required for proteolytic activit[r] ... See full document
8
Hepatitis G Virus Encodes Protease Activities Which Can Effect Processing of the Virus Putative Nonstructural Proteins
... the nonstructural protein region appears to be very similar to that of HCV, except for the substrate specificity of the NS3 ...HCV NS3 serine protease activity is required for all of the ... See full document
5
Mapping the Interactions between the NS4B and NS3 Proteins of Dengue Virus
... where both viral and cellular factors interact and cooperate within an organelle-like replication factory called the replication complex (RC) (for reviews, see references 14 and ...Several nonstructural ... See full document
13
Hepatitis C Virus NS2 Protein Serves as a Scaffold for Virus Assembly by Interacting with both Structural and Nonstructural Proteins
... infectious virus production (data not shown) ...restore virus production to any significant level ...efficient virus production (HJ3-5/p7/YFP/IRES) ...p7 required for infectious virus ... See full document
12
Biosynthesis of Classical Swine Fever Virus Nonstructural Proteins
... Proteolytic processing of polyproteins is considered a crucial step in the life cycle of most positive-strand RNA ...NS2-3 processing has been described as a major difference between the ... See full document
14
In vitro processing of dengue virus type 2 nonstructural proteins NS2A, NS2B, and NS3.
... In order to confirm that the cleavage events observed in vitro occur at the same sites as those utilized in vivo and to confirm the identities of the proteins produced in vitro, we compa[r] ... See full document
11
Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity.
... The data presented above suggested that the 40-aa domain of DEN4 NS2B from residues 1396 to 1435 might be the only region required for protease activity in cis other than the residues di[r] ... See full document
9
Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites.
... Surprisingly, although the 3-5356 construct contained the entire putative NS3 proteinase domain, only a 150-kDa polyprotein was observed whose size and immunoreactivity were consistent w[r] ... See full document
9
Dominant recognition by human CD8+ cytotoxic T lymphocytes of dengue virus nonstructural proteins NS3 and NS1 2a
... three proteins, one or more of them would be able to sensitize target cells for ...from both influenza NS1 and NP proteins were shown to be presented by HLA-B44 to antiinfluenza type A–specific CTLs ... See full document
10
Dengue Virus NS2B/NS3 Protease Inhibitors Exploiting the Prime Side
... for dengue virus protease for P= side substrates to design the scaffold for specific ...against dengue virus protease were measured by fluores- cence resonance energy transfer (FRET)-based ... See full document
10
Identification of T-Cell Epitopes in Nonstructural Proteins of Foot-and-Mouth Disease Virus
... disease virus (FMDV) nonstructural proteins (NSP) was tested using in vitro lymphoproliferative ...these proteins that were efficiently recognized by the ...C virus or reinfected with a ... See full document
11
Proteolytic processing of imported chloroplast proteins
... encoding the envelope transfer domain would have to be acquired (Smeekens et al., 1989). Cheung et al. (1988) have successfully relocated a chloroplast gene, psbA, fused in frame to a sequence encoding SSU transit ... See full document
206
Characterization of Equine Humoral Antibody Response to the Nonstructural Proteins of Equine Arteritis Virus
... the virus control ...12 nonstructural proteins (nsp1 to nsp12) of EAV were PCR amplified from the EAV recombinant virulent Bucyrus strain (rVBS) full-length infectious cDNA clone-containing plasmid ... See full document
Processing the nonstructural polyproteins of sindbis virus: nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in trans.
... From these results and from experiments in which processing was studied at increasingly higher dilution, we have concluded the following: i the viral nonstructural proteinase is located [r] ... See full document
12
Nonstructural proteins 2C and 3D are involved in autophagy as induced by the encephalomyocarditis virus
... viral proteins are required to be further explored, a growing number of studies have demon- strated that the interactions between viral proteins and the cellular proteins associated with ... See full document
11
Membrane Permeabilization by Small Hydrophobic Nonstructural Proteins of Japanese Encephalitis Virus
... NS2A, NS2B, NS4A, and NS4B of flavivirus, processed posttranslationally by cellular signalase in the ER lumen together with viral NS2B-NS3 protease in the cytosol, are predicted to be able to span ... See full document
8
Replication of Murine Hepatitis Virus Is Regulated by Papain-Like Proteinase 1 Processing of Nonstructural Proteins 1, 2, and 3
... the virus that recapitulated the sub- stitutions tested in vitro demonstrated similar processing phe- ...phenotype, processing 22% of CS2 compared to wild-type ...CS2 required a small, ... See full document
11
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