[PDF] Top 20 piRNAs and PIWI proteins: regulators of gene expression in development and stem cells
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piRNAs and PIWI proteins: regulators of gene expression in development and stem cells
... represses expression of the Cbl proto-oncogene in GSCs through the binding of its ...Cbl gene dose reduces aub mutant defects in GSC self-renewal, highlighting the key role of Aub- dependent Cbl regulation ... See full document
13
Understanding development and stem cells using single cell based analyses of gene expression
... weighted gene co-expression network analysis (Langfelder and Horvath, 2008) are first used to project high- dimensional data into a smaller number of dimensions to ease visual evaluation and ...similar ... See full document
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Role of stem cell proteins and microRNAs in embryogenesis and germ cell cancer
... post-transcriptional regulators are ...defective development but at different developmental stages (Wienholds and Plasterk, ...embryonic development, indeed requires a well-organised temporal and ... See full document
14
Screens for piwi Suppressors in Drosophila Identify Dosage-Dependent Regulators of Germline Stem Cell Division
... germline stem cells (gsc) adjacent to the terminal filament (tfc) and in contact with cap cells ...These stem cells divide asymmetrically to form a new germline stem cell and a ... See full document
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Genome wide gene expression analysis in mouse embryonic stem cells
... higher expression than in 3-day-old EBs, suggesting that the proliferation and growth processes triggered during the formation of 3-day-old EBs remain activated after 7 days of spontaneous ...Mcm proteins ... See full document
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goosecoid expression represses Brachyury in embryonic stem cells and affects craniofacial development in chimeric mice
... important regulators of early vertebrate ...the expression of caudal genes overlaps with that of Brachyury in mouse, chick and frog (Meyer and Gruss, 1993; Epstein et ...Brachyury expression in the ... See full document
10
Advanced Gene Manipulation Methods for Stem Cell Theranostics
... of stem cells from patients is becoming more and more ...these stem cells before transplantation for therapeutic purposes is ...the gene activities inside of a cell, researchers have ... See full document
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Role of polycomb proteins Ring1A and Ring1Bin the epigenetic regulation of gene expression
... Ring1 proteins, double mutant Ring1A and Ring1B ES cells show enhanced gene derepression and eventually cessation of cell proliferation (Endoh, 2008), indicating a convergence of regulatory ...ES ... See full document
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The disease-related biological functions of PIWI-interacting RNAs (piRNAs) and underlying molecular mechanisms
... which piRNAs are involved is breast cancer ...BC cells and tumor biopsies [45]. Around 40% of the BC piRNAs are located in the pro- tein coding/small non-coding RNA genomic regions, which suggest ... See full document
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Epigenetic roles of PIWI proteins and piRNAs in lung cancer
... [30]. PIWI proteins contain four members in humans: PIWIL1 (HIWI), PIWIL2 (HILI), PIWIL3 (HIWI3) and PIWIL4 (HIWI2) [29] (Table ...the PIWI subfamily bind to piRNAs and they have limited ... See full document
8
Efficient co-expression of bicistronic proteins in mesenchymal stem cells by development and optimization of a multifunctional plasmid
... derived stem cells used for this research are mesenchy- mal stem cells ...These cells are recruited to tis- sues by chemotactic signals (often mediated by chemokines) and perform key ... See full document
20
Identification and gene expression of versican during early development of Xenopus
... Spatial expression of Xversican mRNA in early Xenopus laevis ...the expression can be detected in the paraxial mesoderm (arrow) and in the midline of neural plate ... See full document
7
Regulation of pepsinogen gene expression in epithelial cells of vertebrate stomach during development
... Jllt I De, Hiol 18 27 1 279 (1994) Rroil'7 o Regulation of pepsinogen gene expression in epithelial cells of vertebrate stomach during development SADAO YASUGI* Department of Biology, Faculty of Scien[.] ... See full document
7
TE studies in Japan: The third Japanese meeting on host-transposon interactions
... increased expression of type I interferon, glutaminase C, glutamate and p17 subunit of Caspase 3, whereas rVpr-injected Irf7-knockout (KO) mice do not, suggesting an involvement of the interferron- dependent ... See full document
5
Mucoxin (Acetogenin) Induce Expression of Pro-Apoptosis Proteins, Bax and P53, in T47D Breast Cancer Cells
... Though mucoxin claimed as a promising anti-cancer, has manufactured and marketed on line all over the world, indepth study of the role of the bioactive materials on cellular level is still limited.In an effort to deepen ... See full document
9
Isolation and gene expression profiling of intestinal epithelial cells: crypt isolation by calcium chelation from in vivo samples
... Following RNA isolation, cDNA was generated using the High Capacity cDNA Reverse Transcription Kit (Applied Biosystems, Foster City, CA, USA) as per the manufacturer’s instructions. Given the low yield of RNA from the ... See full document
9
microRNAs: important regulators of stem cells
... of stem cells miRNAs are key regulators of hematopoiesis in mamma- ...ectopic expression of AAAGUGC seed-containing miRNAs en- hance the primary hematopoietic progenitors ... See full document
7
Comprehensive gene expression analyses in pluripotent stem cells of a planarian, Dugesia japonica
... modification, gene transcription, cell cycle, apoptosis and cell-cell interaction via the cell membrane as well as RNA ...this gene set of the neoblasts in ...comparing gene sets among ...between ... See full document
11
An emerging role for prdm family genes in dorsoventral patterning of the vertebrate nervous system
... a gene-trap screen using the Tol2 transposon system when a transposon inserted into the Prdm14 locus ...Islet2 gene [46], which is re- quired for the development of motor ...Rohon-Beard cells ... See full document
12
Extracellular vesicles-mediated noncoding RNAs transfer in cancer
... transcriptional regulators to influence gene expression, which sets the foundation of the hypothesis that cir- cRNAs transferred by EVs can take part in cell-to-cell communication with recipient ... See full document
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