[PDF] Top 20 A Regulatory Module Controlling Pharyngeal Development and Function in Caenorhabditis elegans
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A Regulatory Module Controlling Pharyngeal Development and Function in Caenorhabditis elegans
... observe pharyngeal defects in rap-1(tm861); sup-37(RNAi) mutants, nor does rap-1(RNAi) suppress pha-1(e2123ts) defects ...regulating pharyngeal develop- ment and ... See full document
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Gain-of-Function Mutations in the Caenorhabditis elegans lin-1 ETS Gene Identify a C-Terminal Regulatory Domain Phosphorylated by ERK MAP Kinase
... during Caenorhabditis elegans development and is negatively regulated by a conserved receptor tyrosine kinase-Ras-ERK mitogen-activated protein (MAP) kinase signal transduction ... See full document
14
Proteomics Profiling and Functional Characterization of Caenorhabditis elegans Excreted/Secreted Proteins
... potentially function directly at the parasite-host or worm-environment ...nematode, Caenorhabditis elegans, as the model to characterize the composition of excreted/secreted proteins with the help of ... See full document
191
The Caenorhabditis elegans spe 38 gene encodes a novel four pass integral membrane protein required for sperm function at fertilization
... Despite the obvious importance of fertilization, our understanding of its molecular details awaits a more complete inventory of its component molecules. In this study, we have identified the spe-38 gene as a new ... See full document
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Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function
... vulval development in syn- Muv mutants was shown to be due to a failure to repress expression of a single gene, lin-3/EGF, in the epidermis (Cui et ...chromatin regulatory mechanisms, and argues for ... See full document
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A compendium of Caenorhabditis elegans regulatory transcription factors: a resource for mapping transcription regulatory networks
... domains function together in DNA binding specificity and, consequently, target gene ...to function in DNA-binding, includ- ing SAND [28], and THAP zinc-finger [29] ... See full document
13
Neuroligin tuning of pharyngeal pumping reveals extrapharyngeal modulation of feeding in Caenorhabditis elegans
... In Caenorhabditis elegans, this process is coordinated by neural circuits that integrate sensory cues from the environment to generate an appropriate behaviour at the appropriate output ...the ... See full document
11
The UPRmt Protects Caenorhabditis elegans from Mitochondrial Dysfunction by Upregulating Specific Enzymes of the Mevalonate Pathway
... the regulatory mechanisms of the pathway typically focus on the transcriptional and post-translational regulation of the second-most upstream enzyme of the pathway, HMG- CoA reductase (also known as ...rhabditis ... See full document
17
RNA Interference: Past, Present and Future
... Around the same time, Guo and Kemphues (1995) demonstrated that sense RNA was as effective as antisense RNA in suppressing gene expression in Caenorhabditis elegans. Fire et al., (1998) built upon these ... See full document
7
Motor neuron M3 controls pharyngeal muscle relaxation timing in Caenorhabditis elegans
... neuron function, and the most informative mechanistically, relied on unc-31 mutant ...wild-type pharyngeal function might produce obvious effects in an unc-31 mutant ...in pharyngeal ... See full document
15
Hunchback and Ikaros-like Zinc Finger Genes Control Reproductive System Development in Caenorhabditis elegans.
... sequenced Caenorhabditis genomes each encode at least one HIL family member and they all contain a highly conserved ortholog of ...C. elegans, ...not function in ...gonadal development, ... See full document
205
Bypassing the Greatwall–Endosulfine Pathway: Plasticity of a Pivotal Cell-Cycle Regulatory Module in Drosophila melanogaster and Caenorhabditis elegans
... for PP2A/B55, because loss of Cdc14 in worms does not cause mitotic defects (Table 4; Roy et al. 2011). Second, nematode PP2A/B55 could be regulated through Endos, be- cause worm Endos with a phosphomimetic mutation of ... See full document
28
A gene regulatory network for cell differentiation in Caenorhabditis elegans
... The network contained 15 nodes. One of the nodes was defined to be a relative position input. After a cell division, this node is set to 0 in the left daughter and 1 in the right daughter. This external input reflects ... See full document
15
Muscle arm development in Caenorhabditis elegans
... The UNC-104 kinesin motor protein is thought to transport the putative muscle arm chemoattractant along motor axons (Hall and Hedgecock, 1991). We therefore counted the number of muscle arms extended in the background of ... See full document
14
Mechanosensory Inputs Influence Caenorhabditis elegans Pharyngeal Activity via Ivermectin Sensitivity Genes
... onto pharyngeal mus- tant for the development of drugs that can destroy popu- cle and nicotinic receptors on the muscle generate the lations of these medically and agriculturally important excitatory ... See full document
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Caenorhabditis elegans RIG I Homolog Mediates Antiviral RNA Interference Downstream of Dicer Dependent Biogenesis of Viral Small Interfering RNAs
... in Caenorhabditis elegans requires Dicer-related helicase 1 (DRH-1), not found in plants and insects but highly homologous to mammalian retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs), ... See full document
15
An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans
... C. elegans STA-1 and STA-2 and representative STATs from other organisms suggests that STA-1 is closely related to mammalian STATs but that STA-2 is more divergent ... See full document
16
Reporter gene constructs suggest that the Caenorhabditis elegans avermectin receptor beta subunit is expressed solely in the pharynx
... arrested development, starvation and eventual ...larval development has been demonstrated in vitro for Haemonchus contortus, where concentrations of avermectin as low as 1 nmol l −1 were sufficient to ... See full document
6
The Effects of Ethanol Exposure on the Development of Caenorhabditis elegans
... C. elegans has been shown to adapt its response to stimuli in the presence of a drug, especially when exposed to that drug prior to the stimulus (Bettinger and McIntire, ...C. elegans, which becomes more ... See full document
7
An Evolutionarily Conserved Pathway Essential for Orsay Virus Infection of Caenorhabditis elegans
... unknown function that is generated by a ribosomal frameshifting mechanism ...C. elegans intestinal cells (5) and leads to morphological disrup- tions of the intestine ...C. elegans ortholog of human ... See full document
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