[PDF] Top 20 Review Article Long noncoding RNA UCA1 can serve as a prognostic marker in human cancer: a meta-analysis

... Two reviewers (Yanghua Fan and Lei Wu) inde- pendently extracted and examined the data from the original articles. Disagreements in the literature assessment were resolved through consensus with a third reviewer (Xingen ... See full document

... predictive marker for metastasis in early-stage, non-small cell lung ...in cancer 16 and acts as a transcriptional regulator for various genes, including those involved in cell proliferation, migration and ... See full document

... subgroup analysis to precisely assess the prognostic effect of NEAT1 on OS and LNM, ...univariate analysis (HR: ...might serve as a reliable molecular marker for poor prognosis in ... See full document

... endogenous RNA; CI: confidence interval; CNKI: China National Knowledge Infrastructure; DFS: disease-free survival; DM: distant metastasis; E2F1: E2F transcription factor 1; E2F5: E2F transcription factor 5; EMT: ... See full document

... the review; any discrepancies were discussed by the ...publication, cancer type, tumor stage, sample size, cutoff value, CASC2 detection method, preoperative treatment, follow-up months, survival ... See full document

... The lncRNAs HOTTIP is asso- ciated with the WDR5/MLL1 and PRC2 chromatin modify- ing complexes and directly binds WDR5 [24], and recent studies showed a close asso- ciation between HOTTIP and HOXA13 in hepatocellular ... See full document

... of cancer. Kim et al. found that HOXA11-AS promoted cancer stem cells (CSCs) self-renewal and EMT in cer- vical cancer cells through regulating the expression of SOX2, Oct-4, Nanog, E-cadherin, ... See full document

... this meta-analysis, including one for esophageal squamous cell carcinoma (ESCC), one for gas- tric cancer (GC), two for colorectal cancer (CRC), two for hepatocellular carcinoma (HCC), two for ... See full document

... present meta-analysis explored that high expression of lncRNA-H19 was positively correlated to poor prognosis and clinicalpathological ...in human solid ...in cancer tissues might also have ... See full document

... Colon cancer-associated transcript 2 (CCAT2) is a recently discovered, long, non-coding RNA (lncRNA) that has been reported to be aberrantly expressed in various tumor ...in human cancers, a ... See full document

... studied; UCA1 expression was explored in human tissue us- ing quantitative PCR or microarray express- ion analysis; 2) the relationship between UCA1 expression and survival was examined; 3) ... See full document

... adverse prognostic effect of MALAT1 over-expression was obtained in different types of cancer (estrogen- dependent cancer: pooled HR = ...urological cancer: pooled HR = 1.952; glioma: pooled ... See full document

... with cancer initiation and progression ...in cancer prognosis [26, 27]. Previous studies have showed UCA1 expression could regulate cancer cell physio- logical processes and was associated ... See full document

... results analysis (four items: follow-up description, survival analysis according to the biological marker, univariate analysis of the prognostic factors for survival, multivariate ... See full document

... Ovarian cancer is one of the most common and lethal gynecological ...ovarian cancer is often at an advanced ...that long noncoding RNAs (lncRNAs) play important roles during ovarian ...ovarian ... See full document

... Based on the above inclusion and exclusion criteria, 19 studies were finally identified for the final meta-analysis, as shown in Figure S1. A total of 1,872 NSCLC patients from People’s Republic of China, ... See full document

... of human tumors, but most are shorter non-coding like microRNAs (miR- NAs) ...with cancer, either by overlap of sequencing libraries with previously an- notated GENCODE lncRNAs, or by de novo assembly of ... See full document

... clinical prognostic biomarker as well as new therapeutic target for ...various cancer subtypes, and developing novel lncRNA-based strategies for diagnosis and targeted therapies appear very promising, bring ... See full document

... In this study, we found that HOTTIP expression levels were higher in OS tissues than in adja- cent non-tumor tissues, and elevated HOTTIP expression was associated with advanced clini- cal stage and distant metastasis, ... See full document

... to long noncoding RNA ROR, such as retinoic acid receptor-related orphan receptor (ROR), risk of relapse (ROR), radius of rota- tion (ROR), and reporting odds ratio (ROR); 2) the studies that were ... See full document