[PDF] Top 20 The role of collagen in cancer: from bench to bedside
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The role of collagen in cancer: from bench to bedside
... Abstract Collagen is the major component of the tumor microenvironment and participates in cancer ...fibrosis. Collagen biosyn- thesis can be regulated by cancer cells through mutated genes, ... See full document
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Pancreatic cancer: from bench to bedside
... in cancer, cardiovascular disease, immune system disease, so it is still in the initial stage of pancreatic cancer research, it can’t be widely used in ...In cancer, Hedgehog may affect normal cells ... See full document
5
Heterogeneity of colon cancer: from bench to bedside
... proceed from the proximal to the distal ...arising from the diverse sides of the colon–rectum as well as for the sensitivity to the therapy, including ...important role in the modulation of the ... See full document
8
B7x—from bench to bedside
... important role in limiting autoimmunity in the peripheral tissues and fine-tuning autoimmune ...prostate cancer its expression is corelated with poorer ... See full document
5
From bench to bedside a comprehensive review of pancreatic cancer immunotherapy
... pancreatic cancer has been well described and it may rep- resent the most important element in PTME [8, 9, 14, ...the role of CD4 T-cells is more ...major role in tumor tolerance [13, ...pancreatic ... See full document
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Pancreatic cancer from bench to bedside: molecular pathways and treatment options
... critical role in cell proliferation and survival during the embryonic ...pancreatic cancer this signaling pathway is found ...pancreatic cancer tumor samples which contributed to the formation of the ... See full document
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Bench to bedside review: The role of glycosaminoglycans in respiratory disease
... results from injury to the lung parenchyma, increased proliferation of mesenchymal cells, and excessive accumulation of connective tissue matrix in the interstitium and intra-alveolar space of the ...factors ... See full document
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How close is the bench to the bedside? Metabolic profiling in cancer research
... metabolites from different pathways have a role in tumor development, and the ability to simultaneously detect and quantitate all these metabolites would give a more global analysis of the state of the ... See full document
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Systemic treatment for lung carcinoids: from bench to bedside
... the role of PRRT in TCs and ACs mainly result from general studies on NENs including a minor percentage of lung ...neuroendocrine cancer subtypes includ- ing 84 lung ... See full document
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Prognostic significance of c KIT in vulvar cancer: bringing this molecular marker from bench to bedside
... the role of this receptor in vulvar carcinomas, as the literature is very limited in this respect and, to our knowledge, no study has been published regarding c-KIT evaluation in squa- mous cell carcinomas of the ... See full document
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Cervical Cancer- Bench to Bedside
... Under funding from Dept. of Biotechnology, Government of India, we first standardized the protocol for generation of DC's and then functionally characterized them (16). Briefly, we obtained peripheral blood ... See full document
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Targeting the IDO1 pathway in cancer: from bench to bedside
... Fig. 2 The IDO1 gene transcripts across tumor samples and paired normal tissues. Data are summarized from The Cancer Genome Atlas, https:// cancergenome.nih.gov/. The Y axis denotes the number of IDO1 ... See full document
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Bench to bedside: A role for erythropoietin in sepsis
... accrue from the administration of EPO within 24 hours of the onset of sepsis and organ ...guided from clinical studies where ranges between 150 and 600 IU/kg have been used ... See full document
8
Linagliptin: from bench to bedside
... findings from animal studies not always reproducible in clinical trials, as was the case with ...the role of incretin therapies in mediating cardiovascular ... See full document
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The role of cognitive activity in cognition protection: from Bedside to Bench
... We find EE has positive influence on normal aging and transgenic AD mouse, which could induce brain structure to produce a variety of changes. The change on anatomy includes the increases of brain weight, thickening of ... See full document
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Tumor angiogenesis. From bench to bedside
... Starting with the hypothesis of Judah Folkman that tumor growth is angiogenesis dependent, this area of research has a solid scientific foundation. More than 30 years ago, Folkman found a revolutionary new way to think ... See full document
8
Antimalarial compounds: from bench to bedside
... effective (S. Looareesuwan, V. Navaratnam and P. L. Olliaro, unpublished). Work is being planned for drugs that are chemical alterations of well-established antimalarial drugs. Artemisone is a metabolically stable ... See full document
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MEK and the inhibitors: from bench to bedside
... Four distinct MAP kinase signaling pathways involving 7 MEK enzymes have been identified. MEK1 and MEK2 are the prototype members of MEK family proteins. Several MEK inhibitors are in clinical trials. Trametinib is being ... See full document
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Antimitochondrial Antibodies: from Bench to Bedside
... genic role of AMA remains a priority for basic and clini- cal research in ...pathogenic role in PBC has been extensively suggested, conclusive data are not ... See full document
12
Dystonia and Cerebellum: From Bench to Bedside
... 6. Concluding Remarks Accumulating evidence suggests that the cortico-basal ganglia-thalamo-cortical, as well as cortico-ponto-cerebello-thalamo-cortical loops, are important in dystonia patho- genesis. The interaction ... See full document
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