[PDF] Top 20 The role of major histocompatibility complex molecules in luteal function
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The role of major histocompatibility complex molecules in luteal function
... ovine luteal cells demonstrated the presence of class II MHC molecules on both large and small cell populations [1,2], suggesting that, in addition to luteal macrophages (which would be included in ... See full document
7
Role of membrane environment and membrane spanning protein regions in assembly and function of the Class II Major Histocompatibility complex
... II Major Histocompatibility complex (MHC-II) is a polymorphic heterodimer that binds antigen-derived peptides and presents them on the surface of antigen presenting ...MHC-II function have ... See full document
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Zika Virus Escapes NK Cell Detection by Upregulating Major Histocompatibility Complex Class I Molecules
... their role in controlling viral ...a major threat to humans due to its pandemic potential and its associa- tion with birth ...The role of NK cells in Zika virus infection is largely un- ...MHC-I ... See full document
11
Human Cytomegalovirus-Encoded Immune Modulators Partner To Downregulate Major Histocompatibility Complex Class I Molecules
... Immune evasion is a hallmark of HCMV. HCMV-infected cells exhibit reduced surface class I molecules due to several independent loci within the US region of the genome (11). The US2 and US11 glycoproteins catalyze ... See full document
9
A Human Herpesvirus 7 Glycoprotein, U21, Diverts Major Histocompatibility Complex Class I Molecules to Lysosomes
... I molecules to lysosomes. A lysosomal targeting function for U21 should manifest itself in a redistribution of class I mole- cules complexed with ... See full document
12
Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules
... I molecules is not a simple linear sequence but rather is embod- ied in the tertiary structure of the luminal and transmembrane regions of ...structural role, allow- ing the luminal domain of US3 to extend ... See full document
8
Role of the adenovirus E3-19k conserved region in binding major histocompatibility complex class I molecules.
... 4778-4783 0022-538X/92/084778-06$02.00/0 Copyright © 1992, American Society for Microbiology Role of the Adenovirus E3-19k Conserved Region in Binding Major Histocompatibility Complex Cl[r] ... See full document
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Soluble HLA-G Inhibits Myeloid Dendritic Cell Function in HIV-1 Infection by Interacting with Leukocyte Immunoglobulin-Like Receptor B2
... soluble molecules of the nonclassical major histocompatibility complex class Ib (MHC-Ib) antigen HLA-G are highly upregulated in the plasma during progressive HIV-1 infection, while levels of ... See full document
8
Development and Use of Multimeric Major Histocompatibility Complex Molecules
... after one in vitro stimulation (33, 43). A number of studies with MHC class II tetramers indicate that the frequency of antigen- specific T lymphocytes, which is in the range of 0.2 to 0.6% of the T cells, is under the ... See full document
5
Use of anti HLA antibodies to mask major histocompatibility complex gene products on tumor cells can enhance susceptibility of these cells to lysis by natural killer cells
... The role of major histocompatibility gene products ...HLA molecules) in rendering tumor cells resistant to natural killer (NK) cell-mediated lysis was investigated by using mouse monoclonal ... See full document
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Interaction of Human Immunodeficiency Virus Type 2 Vpx and Invariant Chain
... I molecules in the ER (10), whereas herpes simplex virus type 1-infected-cell protein 47 inhibits the transport of peptides into the ER by the transporters associated with anti- gen presentation (15, 19, ... See full document
5
B7 Costimulation Is Critical for Antibody Class Switching and CD8+ Cytotoxic T-Lymphocyte Generation in the Host Response to Vesicular Stomatitis Virus
... B7 molecules can prevent induction of anergy ...B7 molecules (9, ...these molecules the subject of intense ...these molecules (B7-1 ⫺/⫺ , B7-2 ⫺/⫺ , or B7-1/2 ⫺/⫺ mice) to investigate the ... See full document
6
Human Herpesvirus 7 U21 Tetramerizes To Associate with Class I Major Histocompatibility Complex Molecules
... MHC molecules to lysosomes, but neither the requirements for binding of U21 to class I MHC molecules nor the mechanism of U21-mediated lys- osomal trafficking are well understood (3, ...MHC molecules ... See full document
11
Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression
... I molecules, ...II molecules to CD4 ⫹ T cells via autophagy (reviewed in reference ...II molecules to CD4 ⫹ T cells after autophagic processing (27, ... See full document
8
Murine cytomegalovirus interacts with major histocompatibility complex class I molecules to establish cellular infection.
... 4182-4189 0022-538X/93/074182-08$02.00/0 Copyright X 1993, American Society for Microbiology JOURNAL OF VIROLOGY, Murine Cytomegalovirus Interacts with Major Histocompatibility Complex C[r] ... See full document
8
Targeted infection of human cells via major histocompatibility complex class I molecules by Moloney murine leukemia virus-derived viruses displaying single-chain antibody fragment-envelope fusion proteins.
... Binding of ScFv-env to human MHC class I molecules. It was important to determine next whether ScFv-env is able to recognize cell membrane-associated MHC class I molecules. MHC class I-positive TE671 cells ... See full document
6
Physical Association of the K3 Protein of Gamma-2 Herpesvirus 68 with Major Histocompatibility Complex Class I Molecules with Impaired Peptide and β2-Microglobulin Assembly
... I molecules in cells expressing K3 as monitored in steady- state comparisons, in pulse-chase experiments, or when cells were treated with proteasome inhibitors ... See full document
8
The biomarkers of immune dysregulation and inflammation response in Parkinson disease
... proteasome function is sup- pressed by intracellular α-synuclein accumulation, i- proteasome will be activated as compensatory to promote α-synuclein degradation ...MHC-I molecules, and the CD 8+ T cells ... See full document
6
Aspects of the cell biology of antigen processing for MHC II
... Macrophages. Macrophages consist of a heterogenous population of bone-marrow derived, phagocytic cells found in many tissues, for example Kupffer cells lining hepatic sinusoids. Unstimulated macrophages are MHC ... See full document
213
Progress in spondylarthritis Progress in studies of the genetics of ankylosing spondylitis
... common complex genetic diseases such as ankylosing spondylitis (AS) rapidly in recent ...the major histocompatibility complex genetics of AS, and of KIR gene variants and the ... See full document
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