[PDF] Top 20 Role of nuclear pore complex in simian virus 40 nuclear targeting.
Has 10000 "Role of nuclear pore complex in simian virus 40 nuclear targeting." found on our website. Below are the top 20 most common "Role of nuclear pore complex in simian virus 40 nuclear targeting.".
Role of nuclear pore complex in simian virus 40 nuclear targeting.
... The nuclear accumulation of virion protein components and large T antigen in nonpermissive NIH 3T3 cells was similar to that in the permissive host, indicating that the ability to use NP[r] ... See full document
12
Walther, Tobias (2002): The role of Peripheral Nuclear Pore Complex (NPC) structures in nuclear transport and NPC architecture. Dissertation, LMU München: Fakultät für Biologie
... the nuclear basket could be removed from the nuclear reconstitution system without affecting NPC formation, these structures are not required for the ...the nuclear envelope never breaks down (Winey ... See full document
150
Inhibition of Nuclear Import and Alteration of Nuclear Pore Complex Composition by Rhinovirus
... polio- virus RNA-dependent RNA polymerase (33); and nucleolin, which binds to the polioviral 3⬘ UTR ...normally nuclear residents. The cytoplasmic accumu- lation of endogenous nuclear proteins was ... See full document
10
The nuclear pore complex
... isolated nuclear envelopes to remove this contaminating material also remove pore complex proteins, making the purification diffi- ...of pore complexes that are found in differentiating and ... See full document
6
Elucidating the Mechanism of mRNA Export Regulation by the Nuclear Pore Complex
... Here we have presented a structural and functional analysis of mRNA export regulation by the NPC. First, we show that the interaction between Gle1 CTD and Nup42 GBM is highly conserved with atomic resolution X-ray ... See full document
84
Importin β modulates the permeability of the nuclear pore complex in a Ran dependent manner
... the nuclear face and including the central channel of the NPC, which contributes to the permeability of the pore (Figure ...other nuclear basket localized Nups, such as Nup50, have been shown to ... See full document
25
Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells
... We next tested whether HIV-1 viruses with mutations on capsid residue N57 require Nup153 expression for infectivity. To this end, we transiently knocked down expression of Nup153 in HeLa cells and challenged the cells ... See full document
29
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome
... In summary, we here discovered recessive mutations in the genes NUP85, NUP133, and NUP160 as 3 monogenic causes of SRNS. Interestingly, all 3 genes and the gene NUP107, in which we found 3 pathogenic alleles, encode ... See full document
17
Interaction of the Vp3 Nuclear Localization Signal with the Importin α2/β Heterodimer Directs Nuclear Entry of Infecting Simian Virus 40
... non-NPC-mediated nuclear entry routes could provide auxiliary access to the ...ER targeting would be instru- mental in clarifying the role of ER in virion nuclear ...SV40 nuclear entry. ... See full document
10
Interaction of the Human Immunodeficiency Virus Type 1 Vpr Protein with the Nuclear Pore Complex
... Vpr nuclear import occurs if the various functions of this viral accessory protein are to be fully ...as nuclear pore com- plexes (NPCs) (17, 35, ...acting targeting signals termed NLSs (34, ... See full document
10
Functional complementation of nuclear targeting-defective mutants of simian virus 40 structural proteins.
... Since what was observed in host cells during infection by polyomaviruses 10, 13, 19, 22, 23, 26 does not reveal the role of individual protein components for nuclear targeting, these obs[r] ... See full document
8
Functional Analysis of the Simian Immunodeficiency Virus Vpx Protein: Identification of Packaging Determinants and a Novel Nuclear Targeting Domain
... the 40-kDa diffusion limit of the NPC must be actively imported via specific pathways following the recognition of cis-acting targeting sequences, termed NLSs (23, 24, ...protein nuclear import have ... See full document
13
The Simian Virus 40 Late Viral Protein VP4 Disrupts the Nuclear Envelope for Viral Release
... The nuclear pore complex connects the cytoplasm and nucleus with an ⬃45-nm- diameter channel ...diameter pore in the nuclear envelope aid the viral life cycle? The formation of a ... See full document
13
Nuclear Export of Simian Immunodeficiency Virus Vpx Protein
... and simian immunodeficiency viruses (SIVs) are distinguished from oncoretroviruses by their ability to infect nondividing cells such as ...limiting nuclear pore complex without membrane ...in ... See full document
12
Simian virus 40 agnoprotein facilitates normal nuclear location of the major capsid polypeptide and cell-to-cell spread of virus.
... Evidence for simian virus 40 late transcriptional control: mixed infections of wild-type simian virus 40 and a late leader deletion mutant exhibit trans effects on late viral RNA synthes[r] ... See full document
9
Mengovirus-Induced Rearrangement of the Nuclear Pore Complex: Hijacking Cellular Phosphorylation Machinery
... the nuclear pores appears to be primarily due to proteolytic degradation of some nucleoporins (protein components of the pore), whereas this effect in cardiovirus-infected cells is triggered by the leader ... See full document
12
The Abundant Nuclear Enzyme PARP Participates in the Life Cycle of Simian Virus 40 and Is Stimulated by Minor Capsid Protein VP3
... (3), nuclear localization signal (NLS) (19), DNA-binding domain (DBD) (5), and Sp1-binding domain (14, 15) are designated ...input nuclear extract (NE) shown in the first lane in each ... See full document
10
Nuclear subcompartmentalization of simian virus 40 large T antigen: evidence for in vivo regulation of biochemical activities.
... To get further insight into the regulation of large-T functions, we have analyzed in vitro biochemical activities of large T ORI DNA binding toward isolated binding sites I and II, as we[r] ... See full document
9
Single molecule imaging to characterise the transport mechanism of the Nuclear Pore Complex
... called nuclear localisation (NLS) signals ...to Nuclear Transport Receptors (NTRs), such as Importin-beta (Impβ) [5]: proteins that facilitate transport by forming multiple interactions with the barrier ... See full document
23
Nuclear Targeting of the Cauliflower Mosaic Virus Coat Protein
... for targeting the virus to the nucleus. The nuclear targeting of CP is not directly regulated by phosphorylation but may be influenced by the presence of the N-terminal acidic region that is ... See full document
8
Related subjects