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[PDF] Top 20 Sirtuin 2 enhances allergic asthmatic inflammation

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Sirtuin 2 enhances allergic asthmatic inflammation

Sirtuin 2 enhances allergic asthmatic inflammation

... and 2 both contain a nuclear export signal and predominantly localize to the cytoplasm ...of allergic inflammation is an area of ongoing research in our ... See full document

16

IL 13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation

IL 13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation

... of allergic inflammation and is sufficient to induce most if not all of the key features of experimental asthma (reviewed in ...gic inflammation has been further emphasized by the finding that IL-13 ... See full document

9

High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice

High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice

... In line with the study objectives, nine-week-old female, wild-type, BALB/c-mice were obtained from the Janvier Labs (Le Genest-Saint-Isle, France) and kept in a 12-h dark/light cycle at 22 °C with laboratory food and tap ... See full document

13

Food allergy enhances allergic asthma in mice

Food allergy enhances allergic asthma in mice

... In order to assess the role of skin sensitization in the asthma process, experiments were also performed in chal- lenged, unsensitized mice and in sensitized, unchallenged mice. In neither group difference in AHR was ... See full document

9

Virus-triggered exacerbation in allergic asthmatic children: neutrophilic airway inflammation and alteration of virus sensors characterize a subgroup of patients

Virus-triggered exacerbation in allergic asthmatic children: neutrophilic airway inflammation and alteration of virus sensors characterize a subgroup of patients

... in asthmatic children [1, ...in asthmatic patients infected with hRV, as shown by altered production of type I IFNs (IFN-α/β) and/or type III IFNs [interleukin (IL)-28 and IL-29] ... See full document

12

Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function

Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function

... variable, 2) be significantly related to the dependent variable, and 3) when both the independent variable and the potential mediator are included in the same model, a previously significant relationship between ... See full document

10

Neuro immune crosstalk and allergic inflammation

Neuro immune crosstalk and allergic inflammation

... In addition to mast cells, other granulocytes are less clearly colocalized with neurons at a steady state. However, eosinophils localize with airway cholinergic nerves after allergen challenges. It has been suggested ... See full document

9

Samsoeum water extract attenuates allergic airway inflammation via modulation of Th1/Th2 cytokines and decrease of iNOS expression in asthmatic mice

Samsoeum water extract attenuates allergic airway inflammation via modulation of Th1/Th2 cytokines and decrease of iNOS expression in asthmatic mice

... polyacrylamide gel electrophoresis gels, and elec- trophoresed. The proteins were then transferred to a nitrocellulose membrane (at 100 V for 2 h). The mem- brane was blocked for 1 h with Tris-buffered saline ... See full document

10

FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype

FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype

... of asthmatic lung inflammation), when compared with DRA- challenged WT mice (Figure ...H 2/M2 cytokines in BAL fluid of DRA-challenged compared to their WT counterpart, thus indicating a greater ... See full document

15

Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice

Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice

... lung inflammation from five airway sections randomly distributed throughout the left lung were eval- uated by one analyst blinded to the groups using a sub- jective scale ranging from 0 to 4 (0, normal; 1, mild; ... See full document

9

PubMedCentral-PMC4976002.pdf

PubMedCentral-PMC4976002.pdf

... Similar to UFP, the size of ENM ranges from 1 to 100 nm in at least one dimension (Box 1). 1 However, they are inherently different from UFP in many aspects (Table 2). Evidence from extensive cellular and animal ... See full document

26

Chitin, Chitinases and Chitinase like Proteins in Allergic Inflammation and Tissue Remodeling

Chitin, Chitinases and Chitinase like Proteins in Allergic Inflammation and Tissue Remodeling

... type 2 allergic in- ...receptor 2 (TLR-2), C-type lectin receptor Dectin-1, and leukotriene B4 recepptor ...of allergic inflammation and tissue ...in allergic ... See full document

9

Allergen presensitization drives an eosinophil dependent arrest in lung specific helminth development

Allergen presensitization drives an eosinophil dependent arrest in lung specific helminth development

... HDM allergic sensitization followed by Ascaris infection markedly upregulated levels of both IL-13 and IL-13Rα2 at 8 dpi when compared with Ascaris infection ...type 2 response in the last protective pheno- ... See full document

17

Arginine metabolic control of airway inflammation

Arginine metabolic control of airway inflammation

... airway inflammation model and is associated with increased expired ...eosinophilic inflammation than WT in the OVA model, yet continue to have airway hyperresponsiveness ...airway inflammation. In ... See full document

13

(R)-albuterol decreases immune responses: role of activated T cells

(R)-albuterol decreases immune responses: role of activated T cells

... Finally, our data suggest that the effects of (R)-albuterol may be mediated by alterations in the activity of the inflammatory transcription factor NF-κB. NF-κB regulates the expression of a wide range of genes involved ... See full document

9

Original Article Hydroxysafflor yellow A attenuates allergic airway inflammation by suppressing the activity of nuclear factor-kappa B in ovalbumin-induced asthmatic mice

Original Article Hydroxysafflor yellow A attenuates allergic airway inflammation by suppressing the activity of nuclear factor-kappa B in ovalbumin-induced asthmatic mice

... OVA-induced asthmatic- mice. These findings suggest that HSYA pre- vents the allergic airway inflammation by diminishing the secretion of related cytokines into the lung ...the allergic ... See full document

10

Complement Component 3C3 and C3a Receptor Are Required in Chitin Dependent Allergic Sensitization to Aspergillus fumigatus but Dispensable in Chitin Induced Innate Allergic Inflammation

Complement Component 3C3 and C3a Receptor Are Required in Chitin Dependent Allergic Sensitization to Aspergillus fumigatus but Dispensable in Chitin Induced Innate Allergic Inflammation

... gic inflammation, we found that C3KO and C3aRKO mice were protected against chitin-dependent sensitization to Aspergillus an- ...from allergic inflammation following challenge with an allergen, less ... See full document

10

Mucosal sensitization to German cockroach involves protease-activated receptor-2

Mucosal sensitization to German cockroach involves protease-activated receptor-2

... ing allergic airway inflammation and AHR using a physi- ologically relevant allergen administered in a physiologically relevant ...airway inflammation in a rabbit model of experimental asthma ...of ... See full document

10

Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation

Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation

... with allergic airway ...induced inflammation in both the short and long term models compared to non-sensitized ...The inflammation seen in the long term model was more diffuse with smaller aggregates ... See full document

10

Anselm, Bettina
  

(2019):


	Early priming of the immune system: Identifying predictive markers of innate immunity and calcium signalling for the development of asthma.


Dissertation, LMU München: Medizinische Fakultät

Anselm, Bettina (2019): Early priming of the immune system: Identifying predictive markers of innate immunity and calcium signalling for the development of asthma. Dissertation, LMU München: Medizinische Fakultät

... Recently, the intriguing concept of an arachidonic acid mediated calcium influx as an alternative to SOCE has been proposed [268]. As the pattern for SOCE-associated calcium signalling and the genes associated with ... See full document

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