[PDF] Top 20 Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules
Has 10000 "Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules" found on our website. Below are the top 20 most common "Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules".
Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules
... of US3. Neither the lu- minal nor the transmembrane domain of US3 alone could mediate association with MHC class I ...tinct functional and structural unit such that the absence ... See full document
8
Human Cytomegalovirus US2 Endoplasmic Reticulum-Lumenal Domain Dictates Association with Major Histocompatibility Complex Class I in a Locus-Specific Manner
... targets class I heavy chains for dislocation remains ...and class I initiates dislocation of class I heavy ...and class I does not appear to signif- icantly alter ... See full document
8
Human Cytomegalovirus Protein US2 Interferes with the Expression of Human HFE, a Nonclassical Class I Major Histocompatibility Complex Molecule That Regulates Iron Homeostasis
... for binding to TfR, and (iii) HFE reduces the endocytosis rate of HFE/TfR/Tf ...a class I MHC molecule, HFE complexes might be modulated by viral anti- gens and might thus manifest another target for ... See full document
6
Structural Definition of Duck Major Histocompatibility Complex Class I Molecules That Might Explain Efficient Cytotoxic T Lymphocyte Immunity to Influenza A Virus
... three functional MHC I loci that provide polymorphic alleles for peptides (25, 26); however, many birds predominantly express only one MHC class I gene, such as in chickens and ducks ...MHC ... See full document
19
Genetic Variability of the Major Histocompatibility Complex Class I Homologue Encoded by Human Cytomegalovirus Leads to Differential Binding to the Inhibitory Receptor ILT2
... lowered binding affinity for ILT2? A possible answer to this question is suggested by a recent report that specific recognition of the viral protein UL18 by ILT2 on CD8 ⫹ T cells mediates non-MHC-restricted lysis ... See full document
10
Human cytomegalovirus US2 destabilizes major histocompatibility complex class I heavy chains.
... Human cytomegalovirus (HCMV) infection causes down-regulation of major histocompatibility complex class I heavy ...free class I heavy chains are proximal ... See full document
10
Human Herpesvirus 7 U21 Tetramerizes To Associate with Class I Major Histocompatibility Complex Molecules
... are functional in binding class I mole- cules, we believe the tetramers may be in a very slow equilibrium with the U21 dimers, in which case an equilibrium dissociation constant for U21 ... See full document
11
Human Cytomegalovirus-Encoded Immune Modulators Partner To Downregulate Major Histocompatibility Complex Class I Molecules
... the human cytomegalovirus (HCMV) has developed a variety of strategies to avoid immune recognition and ...The major histocompatibility complex (MHC) class I antigen ... See full document
9
Molecular Determinants of Peptide Binding to Two Common Rhesus Macaque Major Histocompatibility Complex Class II Molecules
... Mamu class II molecules and of quantitative assays to measure the interaction between Mamu class II mol- ecules and candidate ...and human MHC ...peptide binding to the various alleles ... See full document
11
Binding of Human Cytomegalovirus US2 to Major Histocompatibility Complex Class I and II Proteins Is Not Sufficient for Their Degradation
... Human cytomegalovirus (HCMV) glycoprotein US2 causes degradation of major histocompatibility complex (MHC) class I heavy-chain (HC), class II DR- ␣ and DM- ␣ ... See full document
12
Human Cytomegalovirus Protein US11 Provokes an Unfolded Protein Response That May Facilitate the Degradation of Class I Major Histocompatibility Complex Products
... dase I-like lectin that facilitates the degradation of several misfolded ER proteins (20, ...of class I ...of class I HC in MEFs, but an intact UPR pathway facilitates degradation of ... See full document
12
Inhibition of HLA-DR Assembly, Transport, and Loading by Human Cytomegalovirus Glycoprotein US3: a Novel Mechanism for Evading Major Histocompatibility Complex Class II Antigen Presentation
... the class II pathway, we wondered if there might be other inhibitors of the MHC-II ...of class II proteins involved infection of U373 cells with wild-type HCMV and an HCMV mutant lacking US2 and US3 ... See full document
13
Human Cytomegalovirus pp71 Stimulates Major Histocompatibility Complex Class I Presentation of IE1-Derived Peptides at Immediate Early Times of Infection
... MHC class I molecules when expressed in glioblastoma cells ...MHC class I and HLA-A2 surface expression or presentation of IE1 was seen at 24 or 96 h of ...MHC class I ... See full document
10
Rapid degradation of the heavy chain of class I major histocompatibility complex antigens in the endoplasmic reticulum of human cytomegalovirus-infected cells.
... In HCMVinfected HEL, the heavy chain was synthesized at an increasing rate, but instead of being transported to the cell surface through the Golgi apparatus, it was retained in the ER wi[r] ... See full document
11
Downregulation of Major Histocompatibility Complex Class I Molecules by Kaposi's Sarcoma-Associated Herpesvirus K3 and K5 Proteins
... of class I molecules by K3 and ...MHC class I molecules by accelerating their endocytosis (9, ...of class I mol- ecules, we used an immunofluorescence-based ... See full document
10
Analysis of Pigtail Macaque Major Histocompatibility Complex Class I Molecules Presenting Immunodominant Simian Immunodeficiency Virus Epitopes
... There is now a body of information on a total of 38 M. nemestrina classical MHC class I alleles to draw upon for fur- ther study. Sequence-specific primers can now be designed to detect important alleles ... See full document
12
Prediction of Peptides Binding to Major Histocompatibility Class II Molecules Using Machine Learning Methods
... viruses. Major Histocompatibility (MHC) molecules have an essential role in T-cell activation and initiating an adaptive immune ...MHC-Peptide binding is important in vaccine design and ...the ... See full document
5
Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6
... ATP binding and hy- drolysis are essential for peptide translocation by TAP and is inhibited by HCMV US6 (16, 20, 26, 31, ...ATP binding by TAP. The ATP binding capacity of TAP was assayed with ... See full document
12
Development and Use of Multimeric Major Histocompatibility Complex Molecules
... MHC molecules allow not only for enumeration and characterization of the antigen-specific T-cell response in the peripheral blood or spleens of mice but also in local ana- tomic niches and sites of inflammatory ... See full document
5
Transcriptional and posttranscriptional regulation of class I major histocompatibility complex genes following transformation with human adenoviruses.
... Tumorigenicity of hamster and mouse cells transformed by adenovirus type 2 and 5 is not influenced by the level of class I major histocompatibility antigens expressed on the cells.. The [r] ... See full document
5
Related subjects