[PDF] Top 20 Structural and Functional Features of the Reovirus σ1 Tail

... filamentous tail, which is partly inserted into the virion; a body domain constructed from ␤-spiral repeats; and a globular head with receptor-binding ...␴1 tail is predicted to form an ␣-helical coiled ... See full document

... CONCLUSION Over its 22 year existence, the PredictProtein server has sub- stantially expanded. What started as a service to annotate some aspects of protein structure (secondary structure, sol- vent accessibility and ... See full document

... system compared to the deacetylases. Several other interesting aspects were found in the course of the analyses. As in the phosphorylation and ubiquitination systems, the proportion of erasing enzymes was small compared ... See full document

... biochemical features that are es- sential for function of these molecules, as well as to explore how evolutionary tinkering can give rise to diversity of ... See full document

... C-terminal tail in a stable form. The Autism R102Q mutant protein has structural changes, leading to the 169-190 residues of the C-terminal tail being more dynamic and the protein having an increased ... See full document

... well-defined structural rearrangements and interac- tion events between different proteins accompanies and charac- terizes the TSHR activation ...of structural information, meaning that the main open ... See full document

... 25 Chapter 2 describes the quaternary structure of the GltS and CitS proteins. MemGen itself does not make prediction about the quaternary structure and the evolutionary analysis doesn‟t require any particular prevalence ... See full document

... as functional amyloids for intra- cellular protein release ...histidine tail in a modular protein promotes the self-assembly of the whole construct, favored by the bipolar charge distribu- tion of the ... See full document

... the tail domain, distal to the anti- body ...a structural rearrangement of ␴1 during virion-to-ISVP conversion and contribute new information about the mechanisms of antibody-mediated neutralization of ... See full document

... in reovirus entry and infection, we used ␤1⫺/⫺ cells stably expressing either wild-type ␤1 integrin or ␤1 integrin with altered NPXY ...that reovirus particles enter into ␤1⫹/⫹ cells via a ... See full document

... On the assumption that the viral RNA molecule contains two lengths of dsRNA-3, the three fragments of dsRNA fall into the molar ratios of 3 dsRNA-1, 3 dsRNA-2, and 2 dsRNA-3. This assign[r] ... See full document

... individual structural con- nectome constrains the corresponding functional connectome is unknown, even though its importance is ...ing structural data from individual mice, we virtualized their brain ... See full document

... 9-segment reovirus from nature and present the first structural studies of a member of this ...but functional reovirus and demonstrates the dispensability of several key structural ... See full document

... Abstract Allotetraploid cotton Gossypium hirsutum L. is not only an important crop, but also a model organism used to study such processes as polyploidization, plant genome evolution and the influence of polyploidy on ... See full document

... with functional space being progressively recolonized toward the pre-El Niño ...the functional space), suggesting that the disturbance originated from a different cause than the 1982/83 ...original ... See full document

... The C-terminal region of amphioxus HIF ␣ shared high sequence identity with human HIF1 ␣ C-TAD (Fig. 6A). To test whether this region contains a functional TAD, we deleted (i.e., HIF ␣Ia⌬CTAD) and examined it. ... See full document

... viz functional tags and empty ...fian tail of linguistic events for which unlabeled data is the only learning ...the structural and lexical level in a principled manner. Our structural prior ... See full document

... of reovirus maintained in different laboratories ex- hibit polymorphisms in the ␮2 protein ...a reovirus stock maintained in the labo- ratory of Earl Brown contains Leu and Pro residues at posi- tions 302 ... See full document

... article, structural brain abnormalities as assessed with MRI vary consid- erably across the diagnostic categories of schizophre- nia and affective ...of functional brain changes might be detected underlying ... See full document

... sequence features with the excep- tion of an inverted-terminal-repeat consensus sequence that has similarity to the ends of mariner /Tc1 transposons (K lobutcher and H errick ... See full document