[PDF] Top 20 Structure and expression of the herpes simplex virus type 2 glycoprotein gB gene.

... Anatomy of the herpes simplex virus type 1 strain F glycoprotein B gene: primary sequence and predicted protein structure of the wild type and of monoclonal antibody-resistant mutants.. [r] ... See full document

... crystal structure of the gB ectodomain shows that amino acid 285 of HSV-1 gB is located in the base domain (domain I), which contains putative fusion loops be- lieved to associate with membranes ... See full document

... the expression of gG-1 by different HSV-1 strains, and in all cases, a relatively low expression of this protein was noted in comparison with that of gC-1, as could be deduced from the respective MAb ... See full document

... Background: Herpes simplex virus type 2 (HSV-2) is highly prevalent and major cause of genital herpes in ...genital herpes imply that vaccination is the best ... See full document

... CMV gB homolog, we have observed that in vitro, 5 to 30% of HSV gB2t is proteolytically cleaved between Pro-456 and Leu-457 (27), a location that exactly corresponds to the CMV gB cleav- age ... See full document

... Cysteine mutants of herpes simplex virus type 1 glycoprotein D exhibit temperature-sensitive properties in structure and function.. Glycoprotein D protects mice against lethal challenge [r] ... See full document

... The structure of cell surface glycosaminoglycans is relevant to their recognition by HSV glycoproteins, since the length of the carbohydrate chains (21) and their degree of sulfation (9, 10) determine how ... See full document

... the gB gene sequence cloned in a reverse orientation using Lipo- fectamine 2000 reagent (Invitrogen) according to the manufacturer’s ...⌬gK31-68 virus at a multiplicity of infection (MOI) of 5, and ... See full document

... Human herpes simplex virus type 1 (HSV-1) is a large DNA virus (25) whose infection is characterized by the establishment of latency in neuronal cells (60) and the recurrence of lytic ... See full document

... A region common to herpes simplex virus type 1 and 2 gD amino acid residues 11 to 19 and two sites specific for herpes simplex virus type 2 gD one determined by proline at position 7, th[r] ... See full document

... UL56 gene product of herpes simplex virus (HSV) has been shown to play an important role in viral ...HSV type 2 (HSV-2) and examined its expression and ...The ... See full document

... In previous studies using recombinant viruses, we demonstrated that sequences between -1350 and +30 relative to the start of gC transcription regulate 13-Gal as a viral late gene and tha[r] ... See full document

... To establish permanent CHO cell lines expressing either a membrane-bound or secreted form of gBl, portions of the gBl gene from HSV-1 strain Patton were inserted into an expression vecto[r] ... See full document

... Location of the gene for gF on the HSV-2 genome and the genes for gC 9, 14 and TK 17, 32 on the HSV-1 genome and a summary of the results obtained from screening AraTr viruses that conta[r] ... See full document

... 714 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest To study the effects of missense, nonsense, and deletion mutations of the gB glycoprotein gene of herpes simplex vir[r] ... See full document

... Analysis of the potential coding sequences within the 2.9-kb Sall DNA fragment of HSV-2 revealed an open reading frame of 479 amino acids which began with the methionine encoded at posit[r] ... See full document

... viral gene expression kinetics on host ...layed expression of gB should not greatly influence the initial expansion of gB-CD8 ⫹ T cells in mice infected with ...of gB-CD8 cells ... See full document

... 3668 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The gG-2 glycoprotein gene of herpes simplex virus type 2 HSV-2 was cloned into the mammalian expression vector pMS[r] ... See full document

... Anatomy of the herpes simplex virus type 1 strain F glycoprotein B gene: primary sequence and predicted protein structure of the wild type and of monoclonal antibody-resistant mutants.. [r] ... See full document

... To obtain the complete nucleotide sequence of the region of the HSV-2 genome encoding gC, the protein encoded by the smaller 3'coterminal message, and the upstream and downstream regulat[r] ... See full document