[PDF] Top 20 Subtype-Specific Conformational Differences within the V3 Region of Subtype B and Subtype C Human Immunodeficiency Virus Type 1 Env Proteins
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Subtype-Specific Conformational Differences within the V3 Region of Subtype B and Subtype C Human Immunodeficiency Virus Type 1 Env Proteins
... The subtype B and C nucleotide sequences corresponding to the V3 region of gp120 (HXB2 nucleotides 7111 to 7217) were downloaded from the Los Alamos HIV Sequence Database ...the ... See full document
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Characterization of V3 Sequence Heterogeneity in Subtype C Human Immunodeficiency Virus Type 1 Isolates from Malawi: Underrepresentation of X4 Variants
... Is V3 really variable? The original description of five vari- able regions flanked by conserved regions in the env gene was based on sequence comparisons of subtype B viruses that in- cluded ... See full document
11
Human Immunodeficiency Virus Type 1 Subtype C Molecular Phylogeny: Consensus Sequence for an AIDS Vaccine Design?
... of human immunodeficiency virus type 1 subtype C (HIV-1C) in the AIDS epidemic has been associated with a high prevalence of HIV-1C infection in the southern African ... See full document
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Comparison of Viral Env Proteins from Acute and Chronic Infections with Subtype C Human Immunodeficiency Virus Type 1 Identifies Differences in Glycosylation and CCR5 Utilization and Suggests a New Strategy for Immunogen Design
... viral env genes from people in acute/ early infection with subtype C HIV-1 who were infected via a heterosexual ...HIV-1 env sequences from 68 acutely in- fected subtype ... See full document
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Genetic analysis of human immunodeficiency virus type 1 strains from patients in Cyprus: identification of a new subtype designated subtype I.
... 27 env inserts ( ; 450 bp) from the C2 to V3 region were ...from subtype A (SF170, Rwanda; UG37, Uganda; and Z321, Zaire), three from sub- type B (SF162 and SF2, United States; ... See full document
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Distinct Human Immunodeficiency Virus Type 1 Subtype A Virus Circulating in West Africa: Sub-Subtype A3
... the virus from DDJ369 was more distant from those from DDI579 and DDJ360, respec- tively, than they were from each ...C2-V3 region of the ...A2, B, C, D, F1, F2, G, H, J, and K), A3 ... See full document
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The C3-V4 Region Is a Major Target of Autologous Neutralizing Antibodies in Human Immunodeficiency Virus Type 1 Subtype C Infection
... the V3 region of six subjects were purchased from NMI peptides (Reutlingen, ...V1V2 region (15-mer peptides overlapping by 5 amino acids) of the gp160 were purchased through New England Peptides ... See full document
10
Effect of Amino Acid Substitution of the V3 and Bridging Sheet Residues in Human Immunodeficiency Virus Type 1 Subtype C gp120 on CCR5 Utilization
... chimeric virus LJL, an LAI X4 virus containing the V3 stem from the R5 virus JR-FL, can enter cells expressing CXCR4 but not cells expressing ...LLJ virus containing the V3 crown ... See full document
6
Identification of Subtype C Human Immunodeficiency Virus Type 1 by Subtype Specific PCR and Its Use in the Characterization of Viruses Circulating in the Southern Parts of India
... Human immunodeficiency virus type 1 (HIV-1) subtype C viruses are associated with nearly half of world- wide HIV-1 infections and are most predominant in ... See full document
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Cross-Subtype Neutralization Sensitivity despite Monoclonal Antibody Resistance among Early Subtype A, C, and D Envelope Variants of Human Immunodeficiency Virus Type 1
... early subtype C env proteins had shorter variable loops than did early subtype B env pro- teins (13), suggesting that there are different env protein fea- tures ... See full document
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Cross-Subtype Neutralizing Antibodies Induced in Baboons by a Subtype E gp120 Immunogen Based on an R5 Primary Human Immunodeficiency Virus Type 1 Envelope
... regions within gp120 (C1 to C5) as well as V2 to ...ed within C1, V2, C2, V3, and ...C2, V3, and C5. The most striking differences in peptide specificities were within the C3, ... See full document
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Evolution of the human immunodeficiency virus type 1 subtype-specific V3 domain is confined to a sequence space with a fixed distance to the subtype consensus.
... Human immunodeficiency virus type 1 (HIV-1) strains can be separated into genetic subtypes based on phylogenetic analysis of the envelope ...gp120 V3 domain of ... See full document
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A new subtype of human immunodeficiency virus type 1 (MVP-5180) from Cameroon.
... TSAGUE,3 AND LAZARE KAPTUE3 Max von Pettenkofer Institute, University of Munich, D-80336 Munich,1 and Behring Werke, D-35001 Marburg,2 Germany, and Labo et Transfusion Sanguine, Centre H[r] ... See full document
5
Rapid Detection of Human Immunodeficiency Virus Type 1 Subtype E Infection by PCR
... E virus has been reported to be associated with a higher risk of heterosexual transmission than subtype B virus ...that subtype E virus grew more efficiently in Langerhans cells ... See full document
5
Human Immunodeficiency Virus Type 1 Subtype F Reverse Transcriptase Sequence and Drug Susceptibility
... Most human immunodeficiency virus type 1 (HIV-1) drug susceptibility studies have involved subtype ...the env (24, 25) or gag (19) ...to subtype B ... See full document
5
Testing the Hypothesis of a Recombinant Origin of Human Immunodeficiency Virus Type 1 Subtype E
... the env and vif regions ...(Fig. 1). Intersubtype pairwise distance analyses also showed that the env region of clades A and E are more dissimilar than the gag and pol regions ... See full document
14
Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV 1 subtype B and subtype C
... HIV-1 subtype B and C RT, recombinant RT heterodimers were analyzed in cell-free RNA-depen- dent DNA polymerase assays in the presence of NRTIs ZDV-TP, 3TC-TP, and TFV-DP, or NNRTIs NVP, EFV, ... See full document
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Susceptibility of Recently Transmitted Subtype B Human Immunodeficiency Virus Type 1 Variants to Broadly Neutralizing Antibodies
... one virus variant that seemed resistant to all four ...had virus variants that resisted 2F5 and 4E10 ...epitopes within the mem- brane-proximal external region of gp41, have the largest ... See full document
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Cross-Subtype T-Cell Immune Responses Induced by a Human Immunodeficiency Virus Type 1 Group M Consensus Env Immunogen
... ancestral subtype B env immunogen (An1-envB) induced weak neutral- izing activity in rabbits ...gp140 proteins in guinea pigs similar to those induced by An1-envB ...consensus Env ... See full document
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Human Immunodeficiency Virus Type 1 Subtype B Ancestral Envelope Protein Is Functional and Elicits Neutralizing Antibodies in Rabbits Similar to Those Elicited by a Circulating Subtype B Envelope
... native Env conformations in vivo that were boosted poorly or not at all by these adjuvanted, and probably at least partially denatured, gp120 monomer ...envelope proteins are more effective in boost- ing ... See full document
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