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[PDF] Top 20 Sulfatide Is Required for Efficient Replication of Influenza A Virus

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Sulfatide Is Required for Efficient Replication of Influenza A Virus

Sulfatide Is Required for Efficient Replication of Influenza A Virus

... RNAi against CST mRNA. cDNA sequences 5⬘-GCTTCAACATCATCTGC A-3⬘ (CST401-419, numbering from the ATG codon) or 5⬘-CGACTTCGACTA CCCGGCC-3⬘ (CST337-357) of the CST coding region and 5⬘-CTGGAGTTG TCCCAATTCT-3 ⬘ (GFP29-47) of ... See full document

11

Influenza A Virus M2 Ion Channel Activity Is Essential for Efficient Replication in Tissue Culture

Influenza A Virus M2 Ion Channel Activity Is Essential for Efficient Replication in Tissue Culture

... enza virus-infected cells, input genome vRNA is transcribed in the nucleus to mRNA (primary transcription), and in the pres- ence of a protein synthesis inhibitor further RNA species are not synthesized (reviewed ... See full document

9

Balanced Hemagglutinin and Neuraminidase Activities Are Critical for Efficient Replication of Influenza A Virus

Balanced Hemagglutinin and Neuraminidase Activities Are Critical for Efficient Replication of Influenza A Virus

... reduce virus affinity for sialic acid without completely abrogating sialic acid binding, which is required for virus entry into the host ...for replication of zanamivir-resistant variants (10, ... See full document

6

Importin-α7 Is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice

Importin-α7 Is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice

... analyzed virus replication at different time points after infection by plaque assay ...of influenza virus-infected WT and importin- ␣ 7 ⫺/⫺ mouse ...PR8:NS1-GFP virus-infected WT (A, B, ... See full document

14

Influenza A Virus-Induced Expression of a GalNAc Transferase, GALNT3, via MicroRNAs Is Required for Enhanced Viral Replication

Influenza A Virus-Induced Expression of a GalNAc Transferase, GALNT3, via MicroRNAs Is Required for Enhanced Viral Replication

... the replication of IAV due to the fact that the expression of FGF23 has not been demonstrated in respi- ratory epithelial ...IAV replication by modifying the O-linked glycosylation of unknown cellular ... See full document

14

The RNA polymerase PB2 subunit is not required for replication of the influenza virus genome but is involved in capped mRNA synthesis.

The RNA polymerase PB2 subunit is not required for replication of the influenza virus genome but is involved in capped mRNA synthesis.

... vaccinia virus, which contains mRNA (guanine-7-)methyltransferase activity in addition to RNA phosphatase and guanylyltransferase activities, this poly(A) 1 CAT RNA was translated in vitro into CAT protein ... See full document

6

Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human Cells

Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human Cells

... During the first half of 2015, there were already more than 300 human cases of infection with H5N1 and H7N9 viruses (http: //www.who.int), demonstrating the topicality of both subtypes. Although the minireplicon system ... See full document

11

Efficient Translation Initiation Is Required for Replication of Bovine Viral Diarrhea Virus Subgenomic Replicons

Efficient Translation Initiation Is Required for Replication of Bovine Viral Diarrhea Virus Subgenomic Replicons

... helper virus. Five sg clones derived from the passaged virus contained an identical, silent substitution near the beginning of the NS3 coding sequence (G400U), as well as additional ... See full document

13

The FUSE Binding Protein Is a Cellular Factor Required for Efficient Replication of Hepatitis C Virus

The FUSE Binding Protein Is a Cellular Factor Required for Efficient Replication of Hepatitis C Virus

... Another HCV replicon construct, pLMH14, with the lucif- erase reporter gene was also used to determine the effect of FBP siRNA on HCV translation (51). We set up a highly efficient and sensitive HCV replicon ... See full document

13

Nucleotide Sequence Requirements at the 5′ End of the Influenza A Virus M RNA Segment for Efficient Virus Replication

Nucleotide Sequence Requirements at the 5′ End of the Influenza A Virus M RNA Segment for Efficient Virus Replication

... of influenza A virus consists of eight negative- stranded RNA segments ...For efficient virus replication, all eight viral RNA (vRNA) segments must be packaged into progeny ...are ... See full document

5

Ferret airway epithelial cell cultures support efficient replication of influenza B virus but not mumps virus

Ferret airway epithelial cell cultures support efficient replication of influenza B virus but not mumps virus

... on influenza B viruses, because they have a narrow host range, and are considered more restricted to human hosts than influenza A ...different influenza B viruses isolated between 1987 and 2011, and ... See full document

7

Herpes Simplex Virus 1 ICP22 but Not US1.5 Is Required for Efficient Acute Replication in Mice and VICE Domain Formation

Herpes Simplex Virus 1 ICP22 but Not US1.5 Is Required for Efficient Acute Replication in Mice and VICE Domain Formation

... impaired replication of the 3 ⫻ stop mutant is related to the host’s antiviral IFN ...impaired replication phenotype in the restrictive cell line HEL-299 and MEFs of the CD-1 mouse strain ...the ... See full document

10

The mismatched nucleotides in the 5'-terminal hairpin of minute virus of mice are required for efficient viral DNA replication.

The mismatched nucleotides in the 5'-terminal hairpin of minute virus of mice are required for efficient viral DNA replication.

... active replication origin at the 39 end of MVM DNA is a stretch of perfectly base-paired duplex DNA approximately 50 nucleotides long ...of replication at the 5 9 terminus is part of a hairpin in which ... See full document

8

The Cellular Protein SPT6 Is Required for Efficient Replication of Human Cytomegalovirus

The Cellular Protein SPT6 Is Required for Efficient Replication of Human Cytomegalovirus

... be required for UL69 dimerization and/or multimerization ...be required for its function and/or its ability to form protein ...for virus rep- lication ...be required for efficient ... See full document

10

The African Swine Fever Virus Thymidine Kinase Gene Is Required for Efficient Replication in Swine Macrophages and for Virulence in Swine

The African Swine Fever Virus Thymidine Kinase Gene Is Required for Efficient Replication in Swine Macrophages and for Virulence in Swine

... of virus were plated and overlayered as described above for iso- lation of recombinants, but without X-Gluc in the ...each virus, the plaque size was substantially reduced for the respective TK 2 ... See full document

6

Infection and Replication of Influenza Virus at the Ocular Surface

Infection and Replication of Influenza Virus at the Ocular Surface

... of virus diluted to between approximately 60 and 200 PFU/100 ␮ l; and incubated at room temperature for 1 h, after which the mixture was used to inoculate MDCK cells for a standard plaque ...assay. Virus ... See full document

18

Protein 2A is not required for Theiler's virus replication.

Protein 2A is not required for Theiler's virus replication.

... Theiler’s virus does not have any obvious identity with the 2A proteases of poliovirus and rhinovirus, with protein 2A of hepatitis A virus, or even with the 2A proteins of other ...Theiler’s virus ... See full document

8

Ceramide Suppresses Influenza A Virus Replication In Vitro

Ceramide Suppresses Influenza A Virus Replication In Vitro

... early replication cycle of IAV, which could have been missed with the used 1 MOI, we infected the cells with a high virus inoculum (50 MOI) and assessed the ceramide levels at 6 and 24 hpi ...early ... See full document

16

Autophagy Promotes Replication of Influenza A Virus In Vitro

Autophagy Promotes Replication of Influenza A Virus In Vitro

... are required for autophagosome formation (24, ...are required to activate autophagy and mediate vesicle elongation during the autophagosome formation process ... See full document

17

The N-Terminal Extension of the Influenza B Virus Nucleoprotein Is Not Required for Nuclear Accumulation or the Expression and Replication of a Model RNA

The N-Terminal Extension of the Influenza B Virus Nucleoprotein Is Not Required for Nuclear Accumulation or the Expression and Replication of a Model RNA

... synthetic influenza B virus RNA ...helper virus-infected cells (data not ...of influenza B virus proteins required for the expression of a model ... See full document

6

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