[PDF] Top 20 Thrombus formation in vivo
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Thrombus formation in vivo
... Experimental models of thrombosis. Platelets, red blood cells, monocytes, and granulocytes circulate in blood whereas endothelial cells line the vessel wall. Plasma proteins, including vWF, fibrinogen and other ... See full document
9
RGDV peptide selectively inhibits platelet dependent thrombus formation in vivo Studies using a baboon model
... in vivo the antithrombotic activity of RGDV (Arg-Gly-Asp-Val) tetrapeptide using a baboon thrombosis ...model. Thrombus formation was induced by a device consisting of a tubular segment coated with ... See full document
7
Thrombin initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model
... lacking glycoprotein VI (GPVI), GPVI-depleted mice, and WT mice. Our results indicate that the tissue fac- tor–mediated pathway of thrombin generation, but not the collagen-induced GPVI-mediated pathway, is the major ... See full document
9
Factor XIII A-Subunit V34L Variant Affects Thrombus Cross-Linking in a Murine Model of Thrombosis
... on thrombus formation ...clot formation and lysis in-vitro. In-vivo, V34L increased cross-linking within the thrombus, but did not affect the thrombus size, suggesting that the ... See full document
19
Flow effect on thrombus formation in stenosed coronary arteries: a computational study
... The formation of blood clot is, in most occurrences, a physiological response of human body to vessel injury, necessary for the stop of ...time, thrombus formation is involved in a number of life ... See full document
205
PKCα regulates platelet granule secretion and thrombus formation in mice
... Platelets are central players in atherothrombosis development in coronary artery disease. The PKC family pro- vides important intracellular mechanisms for regulating platelet activity, and platelets express several mem- ... See full document
10
Factor XIII A-Subunit V34L Variant Affects Thrombus Cross-Linking in a Murine Model of Thrombosis
... on thrombus formation ...clot formation and lysis in-vitro. In-vivo, V34L increased cross-linking within the thrombus, but did not affect the thrombus size, suggesting that the ... See full document
19
Tie2 protects the vasculature against thrombus formation in systemic inflammation
... in vivo studies showing that activated endothelial cells can support assembly of the prothrombinase complex required for thrombin and fibrin generation (17, ...in vivo and in vitro (17, 49) and that Angpt-1 ... See full document
15
Coronary vascular occlusion mediated via thromboxane A2 prostaglandin endoperoxide receptor activation in vivo
... disaggregation. Therefore, reversal of coronary occlusion may reflect disaggregation of platelets and/or relaxation of vascular smooth muscle at the site of thrombus formation through specific antagonism of ... See full document
8
β3 phosphorylation of platelet αIIbβ3 is crucial for stability of arterial thrombus and microparticle formation in vivo
... unstable thrombus formation. The mean thrombus volume in DiYF mice formed on collagen was only 50% of that in ...in vivo, were observed in DiYF mice compared to WT ... See full document
10
P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries
... Perfusion chamber experiments. The murine ex vivo perfusion chamber protocol has been described pre- viously (16). Briefly, non-anticoagulated blood was collected from the vena cava of anesthetized mice and ... See full document
10
ACE2 Activation Promotes Antithrombotic Activity
... tenuated by the selective Ang-(1-7) re- ceptor antagonist A-779 (24,25). More re- cently, it was demonstrated that the Ang-(1-7) receptor Mas is present in platelets and the interaction between Ang-(1-7) and Mas on ... See full document
6
In Vitro Evaluation of Intra Aneurysmal, Flow Diverter Induced Thrombus Formation: A Feasibility Study
... thrombi formation was differ- ent for both FDs with different sizes and thus ...The thrombus, resulting from the ...organized thrombus with fibrin and erythrocytes included. The thrombus ... See full document
7
Reduced Thrombus Formation With Silicone Elastomere (Silastic) Umbilical Artery Catheters
... Only one of ten patients with indwelling Silastic cath- eters was shown to have any radiographic evi- dence of arterial thrombosis at the time of cathe- ten removal, while nine of ten si[r] ... See full document
8
DIET AND THROMBUS FORMATION: QUANTITATIVE STUDIES USING AN EXTRACORPOREAL CIRCULATION IN PIGS
... The diet of lard with added cholesterol differed from the lard diet only in the amount of cholesterol, which was sufficient to double the serum cholesterol, yet there was not significant[r] ... See full document
8
<p>Determination of portal vein tumor thrombus blood supply using in vivo cellular magnetic resonance imaging in a rabbit model</p>
... in vivo imaging methods, such as computerized tomography during hepatic arteriography and hepatic portography, are warranted to con fi rm the anatomic con fi guration of the blood vessels that contribute to PVTT in ... See full document
7
Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis
... incipient thrombus formation, and a requirement for repetitive parenteral administration of red cells seems impractical for sustained ...in thrombus formation, a number of platelet-targeting ... See full document
19
Incidence of post myocardial infarction left ventricular thrombus formation in the era of primary percutaneous intervention and glycoprotein IIb/IIIa inhibitors. A prospective observational study
... LV thrombus was defined as an echodense mass with definite margins, contiguous but distinct from the endocardium, adjacent to an area of hypo- or akinetic myocardium ... See full document
5
Intraprocedural Thrombus Formation during Coil Placement in Ruptured Intracranial Aneurysms: Treatment with Systemic Application of the Glycoprotein IIb/IIIa Antagonist Tirofiban
... local thrombus was de- tected at the coil surface in 5 patients, in all of whom the thrombus was locally monitored; these thrombi dissolved without thromboembolic ... See full document
6
Contrast Enhancement Hyperdensity After Endovascular Coiling of Intracranial Aneurysms
... Increased safety of coiling may be attributed to the use of prophylactic agents against thrombus formation, such as heparin, aspirin, clopidogrel, and eptifibatide,2 and the use of succe[r] ... See full document
6
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