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[PDF] Top 20 Transfusion in trauma: thromboelastometry guided coagulation factor concentrate based therapy versus standard fresh frozen plasma based therapy

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Transfusion in trauma: thromboelastometry guided coagulation factor concentrate based therapy versus standard fresh frozen plasma based therapy

Transfusion in trauma: thromboelastometry guided coagulation factor concentrate based therapy versus standard fresh frozen plasma based therapy

... [20,21]. Transfusion of FFP, for instance, carries the risk of transfusion-related lung injury, transfusion-associated circulatory overload, acute respiratory distress syndrome, ... See full document

9

Trauma resuscitation requiring massive transfusion: a descriptive analysis of the role of ratio and time

Trauma resuscitation requiring massive transfusion: a descriptive analysis of the role of ratio and time

... massive transfusion strategies used at our center which highlights the current experience of managing exsanguinating trauma ...appropriate transfusion ratios and timings provides useful information ... See full document

9

Disseminated Intravascular Coagulation With Trauma: Treatment With Exchange Transfusion

Disseminated Intravascular Coagulation With Trauma: Treatment With Exchange Transfusion

... tuna and a rising BUN level and started to bleed profusely from the incision site. Because of the abnormal clotting studies and severe blood loss, the vascular volume was maintained with[r] ... See full document

5

Abo antibody titer study in healthy donors in tertiary care centre of southern rajasthan

Abo antibody titer study in healthy donors in tertiary care centre of southern rajasthan

... following transfusion of non-group specific platelets (specially single donor platelets) and may be more common than is ...ml plasma and in children, there is already less red cell ...exchange ... See full document

7

New evidence in trauma resuscitation - is 1:1:1 the answer?

New evidence in trauma resuscitation - is 1:1:1 the answer?

... blood transfusion practice over the last 100 years have largely occurred based on the ex- perience of military physicians during the major conflicts of the 20th ...for transfusion was carried in 1917 ... See full document

7

Improving outcomes for hospital patients with critical bleeding requiring massive transfusion: the Australian and New Zealand Massive Transfusion Registry study methodology

Improving outcomes for hospital patients with critical bleeding requiring massive transfusion: the Australian and New Zealand Massive Transfusion Registry study methodology

... no standard definition of MT exists in the international literature and use of some definitions may lead to ...exclude trauma patients who die within the first 24 h (‘survivorship bias’) whereas patients ... See full document

10

Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate: a systematic review

Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate: a systematic review

... was based on the percentage of blood volume ...massive trauma bleeding, a ratio-based approach, often integrated into a massive transfusion protocol which aims to coordinate the activities of ... See full document

25

Role of prothrombin complex concentrate in perioperative coagulation therapy

Role of prothrombin complex concentrate in perioperative coagulation therapy

... Thus, plasma prothrombin activity is expected to be higher after the latter set of plasma, but normal pro- thrombin level above 50% is not achieved in this patient at the end of plasma ... See full document

9

Goal directed coagulation management of major trauma patients using thromboelastometry (ROTEM®) guided administration of fibrinogen concentrate and prothrombin complex concentrate

Goal directed coagulation management of major trauma patients using thromboelastometry (ROTEM®) guided administration of fibrinogen concentrate and prothrombin complex concentrate

... haemostatic therapy (half of the patients received goal-directed haemostatic ther- apy within less than one hour after arrival in the ER) and the high fibrinogen to RBC ratio ...latter factor, there have ... See full document

11

Thromboelastometry versus standard coagulation tests versus restrictive protocol to guide blood transfusion prior to central venous catheterization in cirrhosis: study protocol for a randomized controlled trial

Thromboelastometry versus standard coagulation tests versus restrictive protocol to guide blood transfusion prior to central venous catheterization in cirrhosis: study protocol for a randomized controlled trial

... three transfusion strategies (routine coagulation test-guided – ordinary or restrictive, or thromboelastometry-guided) prior to central venous catheterization in critically ill patients ... See full document

10

A randomized controlled trial of fresh frozen plasma for coagulopathy in Russell's viper (Daboia russelii) envenoming

A randomized controlled trial of fresh frozen plasma for coagulopathy in Russell's viper (Daboia russelii) envenoming

... Russell’s viper (Dabaoi russelii) is a snake of major medical importance in South and Southeast Asia [10 – 12]. The major manifestation of envenoming is VICC, which is characterized by decreased levels of fibrinogen, ... See full document

10

Pattern and prevalence of neonatal thrombocytopenia in Port Harcourt, Nigeria

Pattern and prevalence of neonatal thrombocytopenia in Port Harcourt, Nigeria

... are associated with low platelet counts. Newborns who suffer hypoxia or acidosis after birth trauma often develop throm- bocytopenia. This is due to hypoxic injury caused to fetal megakaryocytes which cause the ... See full document

5

VASCULAR HEMOPHILIA

VASCULAR HEMOPHILIA

... The effect of transfusion of fresh-frozen normal plasma (225 ml) on bleeding time, clotting time, prothrombin consumption, and thromboplas- tin generation of patient T.H. Demonstration o[r] ... See full document

17

Dual antiplatelet therapy up to the time of non-elective coronary artery bypass grafting with prophylactic platelet transfusion: is it safe?

Dual antiplatelet therapy up to the time of non-elective coronary artery bypass grafting with prophylactic platelet transfusion: is it safe?

... Despite those strengths, we recognize four limitations. First, this is a single center, retrospective, observational study. The sample size is relatively small given the short period of data collection. Second, no ... See full document

7

Pathogen Reduction of Plasma

Pathogen Reduction of Plasma

... Intercep plasma transfusion, the presence of the all coagulation factors with a normal title, the ab- sence of the haemostasis activation markers, and improved efficacy in the treatment of acquired ... See full document

5

Standard wound management versus negative pressure wound therapy in the treatment of adult patients having surgical incisions for major trauma to the lower limb — a two arm parallel group superiority randomised controlled trial : protocol for Wound Healin

Standard wound management versus negative pressure wound therapy in the treatment of adult patients having surgical incisions for major trauma to the lower limb — a two arm parallel group superiority randomised controlled trial : protocol for Wound Healing in Surgery for Trauma (WHIST)

... The treating surgeon will confirm participant eligibility at the end of the operative procedure but before the wound dressing is applied. Randomisation will be on a 1:1 basis, using a validated computer randomisation ... See full document

8

Utility of thromboelastography and/or thromboelastometry in adults with sepsis: a systematic review

Utility of thromboelastography and/or thromboelastometry in adults with sepsis: a systematic review

... Second, no uniform definitions exist of hypo- and hy- percoagulability. Reference values for patients with sepsis are not widely assessed, and only one study determined cut-off values for a cohort of sepsis patients [9]. ... See full document

11

Acceptance and commitment therapy for chronic pain: protocol of a systematic review and individual participant data meta-analysis

Acceptance and commitment therapy for chronic pain: protocol of a systematic review and individual participant data meta-analysis

... mindfulness-based approaches by Gilpin and colleagues [39], and reviews on other psychological and non-psy- chological pain approaches [40–42], and with regard to certain specified aspects, such as fear-avoidance ... See full document

10

Cost-utility analysis of immune tolerance induction therapy versus on-demand treatment with recombinant factor VII for hemophilia A with high titer inhibitors in Iran

Cost-utility analysis of immune tolerance induction therapy versus on-demand treatment with recombinant factor VII for hemophilia A with high titer inhibitors in Iran

... care system allocates more than 31% of total subsidized funds on hemophilia. This amounts to $103 million of total subsidized. Out of this figure, 38% of this figure is dedi- cated to hemophilia patients with either ... See full document

6

Therapeutic plasma exchange in heart transplantation: role of coagulation assessment with thromboelastometry

Therapeutic plasma exchange in heart transplantation: role of coagulation assessment with thromboelastometry

... Therapeutic plasma exchange (TPE) is a procedure that is used to remove potentially harmful antibodies and toxins from a patient. It is indicated for many disease conditions including autoimmune anemia, autoimmune ... See full document

5

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