[PDF] Top 20 Uncovering the roles of long non-coding RNAs in cancer stem cells

... breast cancer cells ...breast cancer tissues and is upregulated during EMT occurrence in human mammary epithelial ...breast cancer cells are enhanced and exert characteristics of ... See full document

... their roles in EMY via TGF- β signalling several lncRNAs also utilize the MAPK/ERK signalling pathway in EMT (Table ...CRC cells, possibly through inhibition of ERK and p38 signalling ...prostate ... See full document

... Urothelial carcinoma-associated 1 (UCA1) lncRNA is a BC-related oncogene that can directly interact with miR-143, a tumor suppressor in BC, and regulate proliferation and apoptosis of cancer cells. In this ... See full document

... breast cancer patients, HOTAIR overexpression is associated with increased metastasis and reduced overall ...breast cancer cells, where its overexpression alters the H3K27me3 pattern and therefore ... See full document

... breast cancer [91], renal cell carcinoma [93], non- small-cell lung carcinoma [94], hepatocellular carcinoma [97], and cervical cancer tissues ...MM cells [85], a study by Isin et ... See full document

... An increasing number of studies have demonstrated that a number of lncRNAs are not transcriptional noise, but have important functions, such as regulating gene expression at various molecular levels, including protein, ... See full document

... Abstract: Cancer cell invasion and metastasis are the main reason for high mortality (approximately 30%) of colorec- tal cancer (CRC) ...metastasis. Long non-coding RNAs ... See full document

... metastasis cancer related module were enriched for several metabolic ...of cancer [31, 32]. In metastatic cancer, however, such phenomenon has not been fully ...provided cancer cells ... See full document

... LM-4142 cells, respectively, by transient ...transfected cells were subject to puromycin selection; and surviving cells were sorted by FACS based on GFP signal into 96-well plates and then ... See full document

... lncRNA named LOL (lncRNA of luminal) that is upregu- lated in BC and luminal BC. Knockdown of LOL reverses TAM resistance in TamR MCF-7 cells by sponging let-7 miRNAs. 82 LncRNA DSCAM-AS1 promotes TAM resis- tance ... See full document

... Long non-coding RNAs perform a multitude of functions in regulating the cellular processes in NSCLC, such as prolif- eration, cell cycle, apoptosis, invasion, EMT, 20 and cancer ... See full document

... 94 cancer-related lncRNAs in WISP1-overexpressed EC cells that received radiation, and they identified 14 upregulated lncRNAs and 5 downregulated ... See full document

... or cells, so it should be no surprise that the lncRNA-derived fragments HDRF and RDRF can also be detected in plasma of healthy ...pancreatic cancer, elevated CA 19-9 is a poor predictor of pancreatic ... See full document

... Current prostate cancer (PCa) biomarkers such as PSA are not optimal in distinguishing cancer from benign prostate diseases and predicting disease outcome. To discover additional biomarkers, we investigated ... See full document

... that long non‑coding RNAs (lncRNAs) regulate gene or protein expression; however, their function in the progression of hepatic fibrosis remains ...stellate cells (HSCs) is generally ... See full document

... Long non-coding RNAs (lncRNAs) are increasingly implicated as gene regulators in diverse ...important roles in disease progression of various tumors, such as NSCLC, breast ... See full document

... development, stem cell self- renewal, and retrotransposon ...colorectal cancer [83], gli- omas [84] and esophageal squamous cell carcinomas ...gastric cancer tissues was similar to that of Ki67 and ... See full document

... There are CpG islands in the upstream region of the miR-375 gene and aberrant DNA methylation in this gene can be observed in specific melanoma stage [115,116]. His- tone modification of DNA methylation is one vital ... See full document

... independent prognostic factor of OS. The AUC for this prediction model of 5-year OS was 0.742 [89]. Combina- tions of lncRNAs and miRNAs can also promote a better prognostic prediction efficiency. A panel of eight lncR- ... See full document

... a long intervening non-coding RNA (lincRNA) transcribed from the HOXC locus, which participates in epigenetic regulatory processes, cooperates with polycomb repressive complex 2 and is required for ... See full document