[PDF] Top 20 WWP2 is required for normal cell cycle progression
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WWP2 is required for normal cell cycle progression
... regulating cell cycle and apoptosis. WWP2 (WW domain containing E3 Ub-protein ligase 2) is a member of Nedd4- like family, which was first identified in 1988 and shown to regulate protein-membrane ... See full document
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Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells
... for cell viability (reviewed in ...in cell lethality. We found that the RECQ4-MCM10 interaction was required for normal cell cycle progression and for robust origin ... See full document
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Midkine-a Is Required for Cell Cycle Progression of Müller Glia during Neuronal Regeneration in the Vertebrate Retina
... Midkine is a growth factor/cytokine that has multiple roles in neural development, repair, and disease (Sakamoto and Kado- matsu, 2012; Winkler and Yao, 2014; Sorrelle et al., 2017). In malignant tumors, Midkine promotes ... See full document
16
A Fungal Arrestin Protein Contributes to Cell Cycle Progression and Pathogenesis
... are required for fungal virulence ...individually required for fatal infection, the ␣ -arrestin family as a whole contributes to fungal ...and progression of fungal ... See full document
21
URI 1 is required for DNA stability in C elegans
... on cell cycle progression, we examined the nuclear morphology of germline cells in wild-type, uri-1(lf) and uri-1(RNAi)F1 animals stained with DAPI and with the anti-phospho-histone H3 antibody ... See full document
9
β1 integrin is a crucial regulator of pancreatic β cell expansion
... a normal expression repertoire of β-cell markers, normal architectural organization within islet clusters, and a normal ...regulating cell cycle ... See full document
13
/M Phase of the Cell Cycle
... promotes cell proliferation of various lung cancer cell ...in normal human bronchial epithelial cells (NHBE), immortalized human bronchial epithelial cells, BEAS-2B and various NSCLC cell ... See full document
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The Ecdysone inducible zinc finger transcription factor Crol regulates Wg transcription and cell cycle progression in Drosophila
... reduced cell cycles and that overexpression of crol leads to ectopic ...to cell cycle regulators, we used the adult wing phenotype resulting from crol ...on cell death seen in larval wing disc ... See full document
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The polyubiquitin gene Ubi p63E is essential for male meiotic cell cycle progression and germ cell differentiation in Drosophila
... is required cell-autonomously in germ cells for normal chromatin condensation during meiotic prophase and for progression of the meiotic cell cycle through the G2/M transition of ... See full document
10
The Epstein-Barr Virus Immediate-Early Protein BZLF1 Induces Expression of E2F-1 and Other Proteins Involved in Cell Cycle Progression in Primary Keratinocytes and Gastric Carcinoma Cells
... AGS-EBV cell line (a generous gift from Lindsey Hutt-Fletcher) was obtained by G418 selection of AGS cells (a gastric carcinoma cell line) that were infected with a recombinant Akata virus in which a ... See full document
10
Cell Cycle Progression in G1 and S Phases Is CCR4 Dependent following Ionizing Radiation or Replication Stress in Saccharomyces cerevisiae
... into fresh YPD with vigorous shaking at 30°C, and the viable cell counts were determined according to the colony-forming ability of samples selected at the indicated times. All data points represent the averages ... See full document
17
c-JUN prevents methylation of p16 INK4a (and Cdk6): the villain turned bodyguard
... of cell cycle components that has been described to have a direct role in regulating the transcription of p53 and ...genes required for cell cycle progression in tumor ...the ... See full document
6
ERK1 activation is required for S phase onset and cell cycle progression after fertilization in sea urchin embryos
... soluble, cell- penetrating low molecular weight inhibitors with the non- penetrant recombinant ERK phosphatase, we have developed a single cell assay for S phase in sea urchin embryos using the ... See full document
11
Principal Longevity, Leadership Behaviors, and Student Academic Achievement
... and cell migration ...during progression through the cell cycle to mitosis were downregulated in our microarray data, including genes such as anillin (ANLN), cyclin E2 (CCNE2), cell ... See full document
102
Recent advances of cyclin-dependent kinases as potential therapeutic targets in HR+/HER2− metastatic breast cancer: a focus on ribociclib
... “cell cycle*”, “cyclin-dependent kinase 4/6”, “HR + /HER2−”, “metastatic breast cancer”, “CDK4/6 inhibitors”, “Ribociclib”, and ...in cell cycle progression both in normal and ... See full document
13
Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis
... for normal cell cy- cle progression, since antagonists of a v b 3 administered in vivo preferentially caused apoptosis of proliferating vascular cells ...endothelial cell cycle ... See full document
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A MYB (MYBL1) transcription factor is a master regulator of male meiosis
... The transcriptional regulation of mammalian meiosis is poorly characterized, owing to few genetic and ex vivo models. From a genetic screen, we identify the transcription factor MYBL1 as a male-specific master regulator ... See full document
12
Translational control of meiotic cell cycle progression and spermatid differentiation in male germ cells by a novel eIF4G homolog
... is required specifically for male germ cells to undergo meiotic division and proper spermatid ...is required post- transcriptionally for normal accumulation of the core cell cycle ... See full document
7
The folic acid metabolism gene mel 32/Shmt is required for normal cell cycle lengths in Caenorhabditis elegans
... affects cell behaviors during ...increased cell cycle times in the early ...in cell proliferation defects suggested by a reduced germline with less sperm and defective oocytes (Austin et ... See full document
6
The Interfaces Between Signal Transduction Pathways: IGF-1/ mTor, p53 and the Parkinson Disease Pathway
... with normal progression through the cell cycle, it not only acts to stop cell cycle progression but it also shuts down the IGF-1 and mTor pathways [1,22- 23] P53 mediated ... See full document
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