[PDF] Top 20 The Yeast Nuclear Pore Complex and Transport Through It
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The Yeast Nuclear Pore Complex and Transport Through It
... Although perhaps not needed to understand many of the basic principles of NPC-mediated gating, a full understand- ing of transport will ultimately require an understanding of how the FG Nups behave at the ... See full document
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Differential Targeting of Nuclear Pore Complex Proteins in Poliovirus-Infected Cells
... Fluorescent in situ hybridizations. HeLa cells that had been seeded onto 12-mm glass coverslips 2 days prior were mock infected or infected with polio- virus for the indicated times. Where indicated, cells were ... See full document
9
Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes
... We thank H. Oberleithner for the use of lab facilities, P. Vergani for assistance with the preparation of Xenopus laevis oocytes; D. Görlich for the expression plasmids for importin β and Ran-mix; S. Frey for ... See full document
13
Performance Characteristics of the 10hp Induction Machine
... the nuclear pores in infected cells by around 20 nm (a final size of around 50 nm) ...in pore diameter facilitates the translocation of large protein ...the nuclear pore seems to dramatically ... See full document
5
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome
... The nuclear pore complex (NPC) is a large (100 MDa) macro- molecular assembly that spans the nuclear envelope and forms a selective barrier between the cytoplasm and the nucleoplasm ...for ... See full document
17
Importin-α Promotes Passage through the Nuclear Pore Complex of Human Immunodeficiency Virus Type 1 Vpr
... The carboxyl terminus of importin- ␣ is required for the nuclear import of Vpr. It has been suggested that Vpr interacts with importin-␣ (␣1/Rch1 and ␣5/NPI-1) (2, 27, 48, 54). We confirmed whether Vpr directly ... See full document
8
Nuclear pore protein NUP88 activates anaphase promoting complex to promote aneuploidy
... mitosis through an unknown mechanism ...that nuclear transport factors play key roles in regulating chromo- some segregation following NE breakdown (NEBD) and NPC dis- assembly early in mitosis ... See full document
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Herpesvirus Capsid Association with the Nuclear Pore Complex and Viral DNA Release Involve the Nucleoporin CAN/Nup214 and the Capsid Protein pUL25
... the yeast homologues of CAN/Nup214 and hCG1 have been shown to act as “mod- ular duplicates” in the NPC architecture in terms of position and fold arrangements (1), and both were previously shown to be involved in ... See full document
14
Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells
... pass through mitosis (2, ...to transport the preintegration complex (PIC) to the nucleus through nuclear pores (5, ...PIC nuclear translocation ...the nuclear pore ... See full document
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A nuclear targeting system in Plasmodium falciparum
... the nuclear pore complex (NPC) which is a multi-protein channel spanning the nuclear membrane ...effective transport of yeast Gal4-GFP into the nucleus. The nuclear import ... See full document
5
Ran GTPase Regulates Mad2 Localization to the Nuclear Pore Complex
... controlled through the abun- dance of B-type cyclins and Pds1p (also known as Securin) ...budding yeast during ...aphase-promoting complex (APC) ... See full document
7
Mengovirus-Induced Rearrangement of the Nuclear Pore Complex: Hijacking Cellular Phosphorylation Machinery
... the nuclear pores appears to be primarily due to proteolytic degradation of some nucleoporins (protein components of the pore), whereas this effect in cardiovirus-infected cells is triggered by the leader ... See full document
12
Importin β modulates the permeability of the nuclear pore complex in a Ran dependent manner
... the transport axis (Gorlich et ...the nuclear face and including the central channel of the NPC, which contributes to the permeability of the pore (Figure ...other nuclear basket localized ... See full document
25
Interaction of the Human Immunodeficiency Virus Type 1 Vpr Protein with the Nuclear Pore Complex
... the yeast two-hybrid system as a surrogate in vivo inter- action ...the yeast transcription factor GAL4 (preys), whereas the FG-repeat regions of assorted yeast and vertebrate nucleopor- ins were ... See full document
10
Nuclear Pore Complex Function in Saccharomyces cerevisiae Is Influenced by Glycosylation of the Transmembrane Nucleoporin Pom152p
... soluble transport fac- tors that facilitate the translocation across the NPC of cargoes containing nuclear localization signals (NLSs) or nuclear export ...These transport factors, which ... See full document
13
Nucleoporin FG Domains Facilitate mRNP Remodeling at the Cytoplasmic Face of the Nuclear Pore Complex
... and nuclear asymmetric FG domains ...and nuclear Nup1 FG domains) and have concluded that changing the location of these FG domains in the NPC does not dominantly affect bulk transport (Zeitler and ... See full document
21
Elucidating the Mechanism of mRNA Export Regulation by the Nuclear Pore Complex
... the nuclear envelope, separating genetic information contained in the nucleus from the greater cell ...The nuclear pore complex (NPC) is nature’s largest protein channel, and it is the sole ... See full document
84
Selective Removal of FG Repeat Domains from the Nuclear Pore Complex by Enterovirus 2Apro
... for transport receptor-cargo complexes as they transit the central channel of the NPC ...the nuclear envelope that is observed in poliovirus-infected cells ... See full document
11
5-16-2014 12:00 AM The APL5 Subunit of the AP3 Adaptor Protein Complex is Required for Cytokinesis Checkpoint Function in Schizosaccharomyces Pombe
... the nuclear dots formed by the Apl5p-YFP and Apl6p-YFP fusion proteins may be associated with the nuclear ...The nuclear envelope is a barrier between the nucleus and cytoplasm, which is impermeable ... See full document
81
Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export
... RRE/Rev/CRM1 transport complexes (25–27, 29, 29, 30, 70, ...and through the nuclear pore, and turned over in the cytoplasm in the context of single ...masse nuclear export event ...RNA ... See full document
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