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Acute leukemia cell lines

Apoptosis Induction of Armeniacae Semen Extract in Human Acute Leukemia (NALM-6 and KG-1) Cells

Apoptosis Induction of Armeniacae Semen Extract in Human Acute Leukemia (NALM-6 and KG-1) Cells

... KG-1 acute leukemia cell lines (ALL and AML respectively), which were provided by the Pastor Institute of Iran, were grown and sub cultured in RPMI1640 containing 20mM HEPES- buffer and ...

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Common acute lymphoblastic leukemia antigen expressed on leukemia and melanoma cell lines has neutral endopeptidase activity

Common acute lymphoblastic leukemia antigen expressed on leukemia and melanoma cell lines has neutral endopeptidase activity

... lymphoblastic leukemia antigen (CALLA, CD10) translated from a normal human kidney cDNA clone is identical to that of neutral endopeptidase (NEP, EC ...with leukemia and melanoma cell lines ...

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Investigation of the Anti-proliferative and Apoptotic Effects of Aloe vera Extracts on HL60 Human Acute Myeloid Leukemia and MCF-7 Breast Cancer Cell Lines

Investigation of the Anti-proliferative and Apoptotic Effects of Aloe vera Extracts on HL60 Human Acute Myeloid Leukemia and MCF-7 Breast Cancer Cell Lines

... tumor cell lines including HL60 human acute myeloid leukemia and MCF-7 breast cancer cells was studied by cell viability assay, changes in cell morphology, and apoptosis ...

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Retinoic acid  Inhibition of the clonal growth of human myeloid leukemia cells

Retinoic acid Inhibition of the clonal growth of human myeloid leukemia cells

... KG-1, acute myeloblastic leukemia, and the HL-60, acute promyelocytic leukemia, human cell ...both leukemia cell lines was seen with 1 microM retinoic ...leukemic ...

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A novel method to establish glucocorticoid resistant acute lymphoblastic leukemia cell lines

A novel method to establish glucocorticoid resistant acute lymphoblastic leukemia cell lines

... Hypoxic stress can induce glycolysis and the mTOR signaling pathway, which would contribute to chemore- sistance [9, 20, 21, 33]. Moreover, loss of AMPK can induce glycolysis and mTOR pathway also [24, 29, 32]. ...

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Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia

Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia

... apoptotic cell death (21, 22), we tested the hypothesis that sustained growth impairment might be due to induction of ...other cell lines tested (data not ...

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ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

... of acute myelocytic leukemia ...for acute myelocytic ...human acute myelocytic leukemia cell lines NB4 and THP-1 in a time- and dose-dependent ...The cell cycle ...

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In vitro antitumor potential of Bulgarian Tanacetum vulgare L. on human breast adenocarcinoma cells

In vitro antitumor potential of Bulgarian Tanacetum vulgare L. on human breast adenocarcinoma cells

... cancer cell lines from breast, colon, lung and acute T leukemia indicate in vitro cytotoxic activity of ...mouse leukemia L1210 cells ...carcinoma cell line MDA-MB-468 but minor ...

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Synergistic killing effects of homoharringtonine and arsenic trioxide on acute myeloid leukemia stem cells and the underlying mechanisms

Synergistic killing effects of homoharringtonine and arsenic trioxide on acute myeloid leukemia stem cells and the underlying mechanisms

... To further explore the mechanism for the decreased proportion of CD34 + CD38 − cells in KG-1 and Kasumi-1 cells, we examined the effect of HHT on cell differenti- ation of KG-1; however, no differentiation ...

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Protein kinase inhibitors for acute leukemia

Protein kinase inhibitors for acute leukemia

... Sunitinib (SU11248), the first FLT3 inhibitor studied in the clinic, plays a role in inhibiting both tumor angio- genesis and tumor cell proliferation, and usually is used with cytarabine against AML cell ...

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Cytotoxicity Assessment and Apoptosis-related Gene Profiling of Antibody Treated Acute Myeloid Leukemia (AML) and Acute Lymphocytic  Leukemia (ALL) Cancerous Cell Lines

Cytotoxicity Assessment and Apoptosis-related Gene Profiling of Antibody Treated Acute Myeloid Leukemia (AML) and Acute Lymphocytic Leukemia (ALL) Cancerous Cell Lines

... To investigate alterations in the apoptosis-related genes caused by anti-CD45Ra and/or anti-CD123 mAbs treatments, the expression levels of PIM1, ID1, Survivin, cMyc, and MCL1 genes relative to eEF1A1 reference gene in ...

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Chronic Myelocytic Leukemia Terminating in Blast Cell Crisis with Lymphoblastic Characteristics

Chronic Myelocytic Leukemia Terminating in Blast Cell Crisis with Lymphoblastic Characteristics

... in lymphoblast cell lines and in blast cells of some patients with chronic inyelogenous leukemia in acute phase. McCaffrey R, Harrison TA, Parkman R, Baltimore D: Terminal deoxynucleotid[r] ...

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SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines

SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines

... bin/genetics/CGP/cghviewer/CghViewer.cgi?action and MEGAL cells (data not shown). Quantitative genomic PCR confirmed loss of genomic material between SET and NUP214 for both cell lines as indicated by FISH ...

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Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction

Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction

... with acute pro- myelocytic leukemia (APL), and several investigations show that As 2 O 3 induced programmed cell death in APL cell lines ...non-small cell lung cancer cells was ...

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Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling

Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling

... AML cell lines from DSMZ or ATCC. Cell lines were tested for mycoplasma with PCR or Mycoplasma Detection Kit from Lonza (Basle, ...experiment, cell lines or primary cells were ...

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P53 mutation in acute T cell lymphoblastic leukemia is of somatic origin and is stable during establishment of T cell acute lymphoblastic leukemia cell lines

P53 mutation in acute T cell lymphoblastic leukemia is of somatic origin and is stable during establishment of T cell acute lymphoblastic leukemia cell lines

... T cell acute lymphoblastic leukemia (T-ALL) were screened for mutations of the p53 tumor suppressor ...B cell line (HABL) was established. Leukemic T cell lines (HATL) were ...

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Cytotoxic and apoptogenic activity of Bryonia aspera extract on pre-B acute lymphoblastic leukemia cell lines

Cytotoxic and apoptogenic activity of Bryonia aspera extract on pre-B acute lymphoblastic leukemia cell lines

... The apoptosis induced by B. aspera extract were analyzed by Annexin-V/PI double staining kit (eBioscience) based on the manufacturer’s instructions. Briefly, leukemic cells were cultured into 12-well cell culture ...

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Development and Characterization of Tool Compounds Targeting the Runt Domain’s interaction With Cbfβ

Development and Characterization of Tool Compounds Targeting the Runt Domain’s interaction With Cbfβ

... t(8;21) acute myeloid leukemia (AML) cell lines, and reduced the progenitor activity of mouse and human leukemia cells harboring the t(8;21), but not normal bone marrow ...T cell ...

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Stem cells in clinical practice: applications and warnings

Stem cells in clinical practice: applications and warnings

... LC is characterized by an uncontrolled cell growth in the lung tissue. Frequently LC rises from the epithelial cells. The small cell lung carcinoma (SCLC) is the most frequent lung carcinoma. The symptoms ...

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­Cyclic­AMP­efflux­inhibitors­as­potential­therapeutic­agents­for­ leukemia

­Cyclic­AMP­efflux­inhibitors­as­potential­therapeutic­agents­for­ leukemia

... For cell activation, the high affinity FPR-specific agonist (N-formyl-L-methionyl- L-leucyl-L-phenylalanyl-L-phenylalanine, fMLFF) was added at a saturating concentration (100 nM), and acquisition was ...

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