Acute T lymphoblastic leukemia
Prediction of outcomes by early treatment responses in childhood T-cell acute lymphoblastic leukemia: a retrospective study in China
... [12–15]. T- ALL patients are more likely to have a worse steroid re- sponse than B-ALL patients [8, 10, ...established leukemia groups [19 – ...of T-cell receptor (TCR) and clone-specific ...
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The molecular basis of T cell acute lymphoblastic leukemia
... cell acute lymphoblastic leukemias (T-ALLs) are aggressive hema- tologic tumors resulting from the malignant transformation of T cell ...progenitors. T-ALL accounts for 10%–15% of ...
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<p>T-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with <em>NOTCH1</em> mutation as a good prognostic factor</p>
... and T/M-MPAL share cell antigens which characterize T- and myeloid phenotypes, we wanted to test if molecular aberrations frequently found in T-ALL and AML would help in the distinction of ETP-ALL ...
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Expression of the polycomb group gene Bmi1 does not affect the prognosis of pediatric acute lymphoblastic leukemia
... In acute lymphoblastic leukemia, it was reported that CD90+/CD110+ cells in acute lymphoblastic T-cell leu- kemia, and CD9-overexpressing cells in acute lym- phoblastic ...
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P53 mutation in acute T cell lymphoblastic leukemia is of somatic origin and is stable during establishment of T cell acute lymphoblastic leukemia cell lines
... with T cell acute lymphoblastic leukemia (T-ALL) were screened for mutations of the p53 tumor suppressor ...of T-ALL relapse patient ...Leukemic T cell lines (HATL) were ...
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The Philadelphia chromosome in leukemogenesis
... translocation t(9;22)(q34;q11) is known as the Phila‑ delphia chromosome (Ph) and is a hallmark of chronic myeloid leukemia ...In leukemia cells, Ph not only impairs the physiological signaling ...
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Subset derivation of T cell acute lymphoblastic leukemia in man
... blood T cells can be characterized as belonging to either the TH+2 or TH-2 T-cell ...of T cells are TH+2, whereas 80% are TH- 2 utilizing specific ...human T-cell acute ...
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Targeting IRAK1 in T-Cell acute lymphoblastic leukemia
... T-cell acute lymphoblastic leukemia (T-ALL) represents expansion of cells arrested at specific stages of thymic development with the underlying genetic abnormality often determining the ...
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VITAMIN D STATUS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
... Regarding immunophenotyping results in this work it was found that about 2/3 of studied group diagnosed as common ALL (68%).and (32%) of them are of T-ALL. In most studies that discussed ALL immunophenotype it ...
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WILMS' TUMOR GENE 1 (WT1) EXPRESSION IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA
... in acute leukemia below the ranges of normal controls was never ...Band T-ALL; in those analyzing these subtypes separately,controversial results were found, with higher WT1 overexpression detected ...
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Case Report B-acute lymphoblastic leukemia occurring in two pediatric patients with a history of prior Wilms tumors
... on t-AL in the children with neuroblastoma? After treat- ment with similar chemotherapy, why does sec- ondary tumor occur in only a small portion rath- er than all of the patients? We speculate the answer might be ...
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MYC as therapeutic target in leukemia and lymphoma
... lymphocytic leukemia; T-ALL, T-cell acute lymphoblastic leukemia; ALCL, anaplastic large cell lymphoma; BCLU, B-cell lymphoma unclassifiable; BL, Burkitt lymphoma; GC, germinal ...
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A high complex karyotype involving eleven chromosomes including three novel chromosomal aberrations and monoallelic loss of TP53 in case of follicular lymphoma transformed into B-cell lymphoblastic leukemia
... addition, lymphoblastic lymphoma and acute lymphoblastic leukemia (ALL) have also been rarely ...translocation t(14;18)(q32;q21) with BCL2 rearrangements, present in 80 – 90% of all ...
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Drugging the unfolded protein response in acute leukemias
... AML originates from a myeloid-committed hematopoietic stem cell (HSC) and is characterized by acquisition of gen- etic and epigenetic changes [30–35]. These cause aberrant activation of signaling pathways [36–38] ...
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Acute Leukemia Classification based on Image Processing and Machine Learning Techniques
... Acute leukemia is a fast-developing type of blood cancer that gets worse quickly in the children and adults and needs prompt ...for acute leukemia ...the acute lymphoid, acute ...
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Breakthrough Hormographiella aspergillata Infections Arising in Neutropenic Patients Treated Empirically with Caspofungin
... Case description for patient 1. A 23-year-old female was diagnosed with biphenotypic acute leukemia. She received in- duction chemotherapy associating idarubicine, high-dose cyt- arabine, and ...
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Landscape of gene fusions in epithelial cancers: seq and ye shall find
... ALL: Acute lymphoblastic leukemia; AML: Acute myeloid leukemia; APL: Acute promyelocytic leukemia, cholangio cholangiocarcinoma; CML: Chronic myeloid leukemia; CRC: ...
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Reliability analysis of the Chinese version of the Functional Assessment of Cancer Therapy – Leukemia (FACT-Leu) scale based on multivariate generalizability theory
... ALL: Acute lymphoblastic leukemia; AML: Acute myeloid leukemia; ANOVA: Analysis of variance; CLL: Chronic lymphocytic leukemia; CML: Chronic myelogenous leukemia; CRCUS: ...
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Phylogenetic analysis and homology modelling of promising ligands for the treatment of acute lymphoblastic leukemia
... Enzymes are the sparks that start the essential chemical reactions our bodies need to live. They are necessary for digesting food, for stimulating the brain, for providing cellular energy, and for repairing all tissues, ...
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31P MRS analysis of the phospholipid composition of the peripheral blood mononuclear cells (PBMC) and bone marrow mononuclear cells (BMMC) of patients with acute leukemia (AL)
... with acute leukemia (18 with ALL and 37 with AML) and from the BMMC of 44 patients with acute leukemia (11 with ALL and 29 with ...with acute leukemia ...
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