amorphous state
SOLID STATE CRYSTALLINITY, AMORPHOUS STATE, AND ITS IMPLICATIONS IN THE PHARMACEUTICAL PROCESS
... to amorphous form may occur during various pharmaceutical ...solid state crystallinity, amorphous state and to address the current challenges faced by pharmaceutical formulation, process ...
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A Review of Polymorphism and the Amorphous State in the Formulation Strategy of Medicines and Marketed Drugs
... In the pharmaceutical development field, choosing the polymorph of optimal bioavailability, processability, and stability is the goal of every medicinal product developer. However, sensible approach is needed as for ...
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Ion Species/Energy Dependence of Irradiation Induced Lattice Structure Transformation and Surface Hardness of Ni3Nb and Ni3Ta Intermetallic Compounds
... from the orthorhombic ordered structure to the amorphous state even at room temperature. The critical ion fluence which causes the amorphization, however, depends on the ion spe- cies and/or ion energy. In ...
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Journal of Applied Pharmaceutical Science
... DSC thermograms of DMP-pluronic F-68 systems are shown in Fig.(5). DMP (Fig. 5, trace A) showed a sharp endothermic peak at 252.49 °C corresponding to its melting point (Council of Europe, 2014) with a fusion enthalpy ...
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FORMULATION AND EVALUATION OF FAST DISSOLVING ORAL FILM OF LEVOCITRAZINE DI HYDROCHLORIDE BY SOLVENT CASTING TECHNIQUE
... The aim of the present investigation was to enhance the aqueous solubility and therapeutic efficacy of the drug by formulating solid dispersions (SDs) of vilazodone (VZD) with a hydrophilic carrier Poloxamer 188(PXM) by ...
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SOLUBILITY ENHANCEMENT OF MICONAZOLE NITRATE FOR FORMULATION AND EVALUATION OF MUCOADHESIVE GEL
... the amorphous state tend to have higher ...its amorphous state, because no energy is required to break up the crystal lattice during the dissolution process In solid dispersions, drugs are ...
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Thermal Crystallization and Electron Irradiation Induced Phase Transformation Behavior in Zr66 7Cu33 3 Metallic Glass
... An amorphous state can be realized by various processes such as rapid quenching of liquid (LQ) or vapor phase (VQ), mechanical alloying, severe deformation and ...solid state and a large number of ...
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Understanding the role of low glass transition temperature excipients in the mitigation of amorphisation on mechanical processing
... The amorphous state produced on mechanical and co-mechanical activation is metastable from a thermodynamic perspective, and will inevitably undergo a transformation to the crystalline state (Hilden ...
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Feasibility study of a Ge₂Sb₂Te₅-clad silicon waveguide as a non-volatile optical on-off switch
... the amorphous state, are shown by a solid red line in ...crystalline state is shown by a solid blue line using the right-hand side ...the amorphous “ON” state, as additional coupling ...
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Formulation and evaluation of solid dispersions of fenofibrate for dissolution rate enhancement
... solid dispersion due to presence of drug in amorphous state as compared the physical mixtures and pure drug, where drug is present in crystalline state [9].In case of various ibuprofen solid ...
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Pharmaceutical solvates, hydrates and amorphous forms: a special emphasis on cocrystals
... However, amorphous solids are characterized by the presence of ran- dom atomic structure and a short range order of ...the amorphous state shows no symmetry ...an amorphous solid may not be a ...
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Variation of Microstructure and Electrical Conductivity of Amorphous AgInSbTe and SbTe Films during Crystallization
... AIST and ST films as shown in Fig. 7, where a random atomic modular patterns and selected area diffraction (SAD) patterns refer the as-deposited films to amorphous state. Fine crystallites (black contrast) are ...
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Effect of Tin Addition on the Properties of Electroless Ni P Sn Ternary Deposits
... addition improves the formability of the amorphous phase. The degree of amorphous state increases with the increasing of Sn content. At the same time, the hardness of deposit decreases and the ...
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Computer Simulation of Precipitation Process in Si/Ge Amorphous Multi Layer Films: Effects of Cu Addition
... We have simulated the precipitation process in Cu-free and Cu-added amorphous Si/Ge multilayer films by a molecular dynamics method. Four specimens were prepared: Si/Ge, Si/(Ge + Cu), (Si + Cu)/(Ge + Cu) and ...
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Solubility Enhancement of BCS Class II Drug By Solid Dispersion Technique – Fabrication and Evaluation.
... Solid dispersion is drug dispersed in a biologically inert matrix. Drug in soluble hydrophilic carrier improves the dissolution rate by reducing particle size, higher porosity, drug is in amorphous state, ...
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Oxidation Behavior of Ca Based Bulk Amorphous Materials
... the amorphous state is always higher than that of the same alloy in the crystalline ...the amorphous alloy, if the same surface oxides are formed in both ...the amorphous alloys to demonstrate ...
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Determination of traces of crystalline cefuroxime axetil content in cefuroxime axetil amorphous drug substance using powder X Ray Diffraction (PXRD) Technique
... the amorphous state is metastable and less thermodynamically stable relative to the crystalline state, there is always the potential for unexpected crystallization during ...of amorphous to ...
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Journal of Applied Pharmaceutical Science
... Solid state characterization revealed that the enhanced drug dissolution was due to the presence of the drug at its amorphous state as a result of the formation of solid solution with the polymeric ...
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Large scale fabrication of boron nitride nanotubes with high purity via solid state reaction method
... it can be roughly concluded that the nanotube is com- posed of BN. Figure 2d shows the EDS result of an encap- sulated particle. Dominating peaks of B, N, Fe, and Cu along with a low level of Cr are detected. Apparently, ...
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Magnetostriction in Amorphous Co66Fe34 Microcantilevers Fabricated with Hydrogenated Amorphous Silicon
... hydrogenated amorphous silicon (n+a-Si:H), was deposited by plasma enhanced chemical vapor deposition, defined using DWL and patterned by reactive ion etching ...
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