bone marrow-derived macrophage
Original Article Effect of rTsP53 on the M1/M2 activation of bone-marrow derived macrophage in vitro
... activate bone-marrow derived macrophage (BMDM) into M2 macrophage and stop M1 macrophage ...(+) macrophage was ...
16
Evaluation of polarising stimuli on bone marrow derived macrophage phenotypes in two models of neuroinflammation
... It has been acknowledged for over a decade that macrophages adopt different phenotypes in response to different stimuli. In the past few years, it has become apparent that macrophages infiltrate the brain under certain ...
182
M2 bone marrow-derived macrophage-derived exosomes shuffle microRNA-21 to accelerate immune escape of glioma by modulating PEG3
... It was reported that glioma cells exosomes deliver miR- 148a to accelerate proliferation and metastasis of glio- blastoma [38]. Other study also reported that glioma associated-human mesenchymal stem cells-derived ...
17
Aging impairs peritoneal but not bone marrow derived macrophage phagocytosis
... Bone marrow progenitors, differentiated in vitro, showed no age- related defect in macrophage phagocytosis ...the bone marrow environment in old mice could impact on macrophage ...
10
Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
... BMDM: bone marrow‑derived macrophage; C4HSU: control helper‑dependent adenoviral vector; cDNA: complementary deoxyribonucleic acid; C/EBP: CAAT enhancer binding protein; COX‑2: ...
12
Anti osteoclastogenic activity of matairesinol via suppression of p38/ERK NFATc1 signaling axis
... mouse bone marrow-derived macrophage cells (BMMs) were cultured for 4 days in the presence of RANKL and M-CSF with the vehicle (DMSO) or ...
8
New application of anti-TLR monoclonal antibodies: detection, inhibition and protection
... BM-cDC: bone marrow-derived conventional dendritic cell; BM-MC: bone marrow-derived macrophage; BM-pDC: bone marrow-derived plasmacytoid dendritic ...
8
Mast cell–derived angiopoietin 1 plays a critical role in the growth of plasma cell tumors
... ng/ml). Bone marrow mast cells, obtained from C57BL/6 mice (National Cancer Institute), were cultured with 10 ng/ml IL-3 (these are referred to here as BMMCs) or with 100 ng/ml SCF plus 50 ng/ml IL-6 plus ...
10
Role of the IL-33-ST2 axis in sepsis
... BMDMs: Bone marrow-derived macrophages; CLP: Cecal ligation and puncture; DAMPs: Danger-associated molecular patterns; DCs: Dendritic cells; GMC- SF: Granulocyte macrophage colony-stimulating ...
9
Difference in mobilization of progenitor cells after myocardial infarction in smoking versus non-smoking patients: insights from the BONAMI trial
... BMC: bone marrow-derived cell; BMMC: bone marrow mononuclear cell; BONAMI: Bone marrow in acute myocardial infarction; CFU: colony forming unit; CFU-EC: endothelial cell ...
12
IL-15 Generates IFN-γ-producing Cells Reciprocally Expressing Lymphoid-Myeloid Markers during Dendritic Cell Differentiation
... BM: bone marrow; BMDCs: bone marrow-derived dendritic cells; BMDMs: bone marrow-derived macrophages; CD: cluster of differentiation; CFU: colony-forming unit; DCs: ...
17
Cellular and molecular basis of wound healing in diabetes
... Diabetic foot ulcers (DFUs), a leading cause of amputations, affect 15% of people with diabetes. A series of multiple mechanisms, including decreased cell and growth factor response, lead to diminished peripheral blood ...
5
Intramuscular injection of human umbilical cord-derived mesenchymal stem cells improves cardiac function in dilated cardiomyopathy rats
... remains the ultimate treatment for DCM [5]. Due to the in- vasive and costly nature of heart transplantation, alternative therapies with higher accessibility are imperative for pediatric DCM. Mesenchymal stem cells ...
10
Stem cells in retinal regeneration: past, present and future
... Diseases that are caused primarily by single gene defects, such as STGD, represent a greater challenge for iPSC-based therapies. This is because iPSCs generated from a diseased individual, as well as their differentiated ...
10
Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
... Recent studies indicated that different types of MSC therapy or combined therapies with some unique bio- technology factors can stimulate cutaneous wound healing [28–31]. Current studies have report that a new ...
10
Meniscus repair using mesenchymal stem cells – a comprehensive review
... study where 22.4 million precultured autologous MSCs along with 1 ml nucleated cells (isolated from fresh bone) and 1 ml 10% v/v platelet lysate were intra-articularly injected into a 46-year-old male patient ...
10
Pathogenic roles of CXCL10 signaling through CXCR3 and TLR4 in macrophages and T cells: relevance for arthritis
... CXCL10 stimulated the expression of RANKL, TNFα, and IL-6 in CD4 + T cells in a CXCR3-dependent and TLR4-dependent manner (Fig. 2a, b). Enhanced levels of RANKL and TNFα play an essential role in inflamma- tion and ...
14
Role of Bone Marrow-Derived Mesenchymal Stem Cells Differentiate into β Cells in the Pancreatic Microenvironment
... BM-MSCs derived from male SD rats into diabetic female SD rats and showed that MSCs survived, and expressed insulin as well as genes associated with beta-cell ...
14
Percutaneous Intramyocardial Delivery of Mesenchymal Stem Cells Induces Superior Improvement in Regional Left Ventricular Function Compared with Bone Marrow Mononuclear Cells in Porcine Myocardial Infarcted Heart
... types, bone marrow-derived mononuclear cells (BMMNC) have been most widely applied in clinical trials and basic research ...[2-7]. Bone marrow-derived mesenchymal stem cells ...
10
NOS2 deficiency has no influence on the radiosensitivity of the hematopoietic system
... BM: bone marrow; BMMNCs: bone marrow mononuclear cells; BFU-E: burst-forming unit erythroid; CFU-GM: colony forming unit-granulocyte, macrophage; CFU-GEMM: colony forming ...
11