cell signaling
Recent Advances in T Cell Signaling in Aging
... stress-associated protein kinases JNKs (c-jun amino terminal kinase), also known as SAPKs (stress-associated protein kinases) and the p38 cas- cade, demonstrates the diverse nature of the MAPK superfamily of enzymes ...
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Characterization of Cell to Cell Signaling Deficient Pseudomonas aeruginosa Strains Colonizing Intubated Patients
... Cell-to-cell signaling involving N-acyl-homoserine lactone compounds termed autoinducers (AIs) is instru- mental to virulence factor production and biofilm development by Pseudomonas ...of ...
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Bacterial cell to cell signaling promotes the evolution of resistance to parasitic bacteriophages
... Our results have potential clinical relevance because QS is a key regulator of important virulence factors in P. aeruginosa. First, it is possible that phage selection might increase the proportion of vir- ulent P. ...
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Cell cell signaling during neurogenesis: some answers and many questions
... Int J D 8iol ~2 1"7 139(\998) 127 Cell cell signaling during neurogenesis some answers and many questions KRISHNA M BHAT> Department of Ceff Biology, Emory University School of Medicine, Atlanta USA C[.] ...
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Roles of Cell Signaling Pathways in Cell-to-Cell Contact-Mediated Epstein-Barr Virus Transmission
... of cell signaling pathways on cell-to-cell contact-mediated EBV transmission and ...on cell-to-cell contact-mediated EBV transmission (top) and EBV replication ...on ...
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Zap1 Control of Cell-Cell Signaling in Candida albicans Biofilms
... Our study addresses the role of a C. albicans transcription factor, Zap1 (zinc-responsive activator protein; also called Csr1), which governs the balance of yeast and hyphal cells in biofilms. Zap1 has been identified as ...
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T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity
... T cell in patients with SLE presents a fascinating pheno- type, which is now better understood after gaining insight into the underlying cell signaling and gene ...specific cell functions ...
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Molecular mechanisms of cell cell signaling by the Spemann Mangold organizer
... ABSTRACT We review how studies on the first Spemann-Mangold organizer marker, the homeobox gene goosecoid, led to the discovery of secreted factors that pattern the vertebrate embryo. Microinjection of goosecoid mRNA ...
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Cell cell signaling and adhesion in phagocytosis and early development of Dictyostelium
... of cell biological, biochemical and molecular genetic approaches that can be used in this ...or cell behavior within the multicellular organism can be easily followed by optical tools and digital ...
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Yersinia proteins that target host cell signaling pathways
... The other effector involved in antiphagocytosis, YopH, is homologous to eukaryotic tyrosine phosphatases (18) and has the highest activity of all tyrosine phosphatases known today (19). High expression of YopH alone is ...
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The Role of CYLD in Blocking Oncogenic Cell Signaling in Melanoma
... melanoma cell proliferation and migration, searching for therapeutic drugs targeting these signaling pathways seems ...CYLD-related signaling pathways in cancer therapeutic design can be classified ...
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Parathyroid hormone and cell signaling in bone remodeling
... the current number of their members. However, the population of the opposing cells also affects this rate. In Lemaire et al.’s model, it is assumed that responding osteoblasts do not experience apoptosis. They must ...
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Cell-to-cell signaling through light: just a ghost of chance?
... Non-specialized cells are hardly able to emit light with an intensity above the level of ambient illumination under natural conditions. Within a colony of standard model cells (without naked eye visible bioluminescence ...
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Force-dependent cell signaling in stem cell differentiation
... Recently, the linkage between nucleoskeleton and cyto- skeleton (LINC) complex, a specialized structure that includes the nuclear lamin and SUN which binds to the KASH domain of the actin-associated Nesprins, was identifi ...
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Abnormalities of T cell signaling in systemic lupus erythematosus
... T cell surface adhesion molecule that recog- nizes and binds to its ligand hyaluronic acid in tissues and thus enables T cells to migrate into peripheral ...CD44 signaling cascade [28], suggesting that ...
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Linearity in Cell Signaling Pathways
... understanding signaling pathway function Signaling pathways have been well-characterized over the last few decades, and the molecular interactions that govern each pathway are largely ...a signaling ...
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Mtor and its role in cell signaling
... According to Rozengurt (2014), mTOR is related to the insulin receptor substrate (IRS1-4), as well as G proteins action (ENU) in pancreatic cancer cells (PDCA). The author showed that the P13K / Akt / mTOR route when ...
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Cell signaling in trophoblast uterine communication
... and Armant, 2004). Therefore, uterine LPA secretion could activate HBEGF shedding from blastocysts in apposition to the uterine wall, signaling its presence to the adjacent uterine epithelium (Fig. 1A). Several ...
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Signaling in the stem cell niche: regulating cell fate, function and plasticity
... key signaling factors such as WNT, Notch and BMP (Roberts et ...stem cell niche in the lung airway (Ruiz et ...stem cell regulation. For example, endothelial cell signaling plays a key ...
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Viral Modulation of T-Cell Receptor Signaling
... of signaling molecules to lipid rafts and is likely to be central to the ability of MV to modulate TcR ...T cell and the TcR signaling ...TcR signaling defects remain to be ...
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