Chromatin structure and function
Advanced microscopy methods for visualizing chromatin structure
... a b s t r a c t In the recent years it has become clear that our genome is not randomly organized and its architec- ture is tightly linked to its function. While genomic studies have given much insight into genome ...
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Chromatin remodelers: from function to dysfunction
... local chromatin structures correlating with a persistent activation or repression of certain DNA dependent ...global chromatin architecture that could respond to the one or other signal and being not ...
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piRNA clusters and open chromatin structure
... also function by promoting the activity of histone-modifying enzymes that contribute to the main- tenance of open chromatin conformation ...of chromatin boundaries are associated with active ...
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Do Transcription Factor Affect Chromatin Structure
... infections, structure affect transcription factor binding cannot be considered for signed ...with chromatin factors affect phenotypic ...the chromatin accessibility assays discussed here has inherent ...
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Chromatin Remodeling Factors Isw2 and Ino80 Regulate Checkpoint Activity and Chromatin Structure in S Phase
... not function through their known biochemical activities, we speculate that Isw2 and Ino80 function in a currently unknown ...ATP-dependent chromatin remodeling factor, Fun30, and its mammalian ...
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Crosstalk between chromatin structure, cohesin activity and transcription
... and chromatin structure impact each other in ...in chromatin structure that preferentially take place at promoters; these changes include a significant increase in the occupancy of the − 1 and ...
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A Role for the Nucleoporin Nup170p in Chromatin Structure and Gene Silencing
... the function of Nup170p in subtelomeric gene silencing is linked to its physical association with ...Because chromatin association of Sir4p is considered a prereq- uisite for its role in silencing, we ...
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Studies on the role of histones in the structure and function of chromatin
... In the preparation of chromatin samples for template activity studies we have, therefore, routinely extracted the original purified sheared chromatin three times with 0.15 M NaC1 - 0.[r] ...
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In the loop: how chromatin topology links genome structure to function in mechanisms underlying learning and memory
... of chromatin topology and genomic stability in cognitive ...cognitive function in neural progenitor cells ...compartmentalization, chromatin looping, and DSB formation that occur in response to ...
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Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function
... Repressive chromatin is essential for nuclear organization, genome do- main structure, repression of repetitive elements, genome stability, and regulation of protein-coding ...
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The function of chromatin modifiers in lineage commitment and cell fate specification
... the structure of chromatin are known to be important for various aspects of metazoan biology including development, disease and possibly ...remodel chromatin, their chromatin binding profiles ...
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Cell Structure and Function
... does chromatin consist of? It consists of DNA bound to ...condensed chromatin that contain genetic information that is passed from one generation of cells to the ...
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Chromatin structure and DNA damage repair
... repair, chromatin remodelling is most likely a ...on chromatin remodelling with respect to the cellular response to DNA damage, with emphasis on the response to lesions resolved by nucleotide excision ...
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Chromatin, DNA structure and alternative splicing
... [60] . In this study, they observed that nucleosomes impose a bar- rier for RNAPII progression, increasing pause density and duration and decreasing RNAPII apparent velocity. According to their model, when RNAPII finds a ...
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A Model for the Structure of Chromatin in Mammalian Sperm
... By using available data on the composition of the mouse (70) and bull (5) sperm nucleus, amino acid sequence data on fish (1-3, 15, 16, 41) and bull (24) protamine, and a great deal of t[r] ...
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Dynamic Nuclear Architecture and Chromatin Function (EuroDYNA)
... 8 Finding a cure for cancer : the holy grail of science Understanding the pathways The understanding of individual disease response pathways is increasing as Pavel Kovarik from the Max F. Perutz Laboratories at the ...
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Chromosome arrangement and chromatin structure in mammalian spermatogenesis
... The pattern of acetylated histone H4, histone macroH2A and histone H2AZ were studied in marsupial and mouse somatic and meiotic cells, in order to establish the patterns of [r] ...
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Evaluation of sperm chromatin structure in boar semen
... of chromatin structure, which has a key role in male ...evaluating chromatin structure are worth implementing during the breeder’s exploitation, as abnormal protamination may be an individual ...
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Glycolytic metabolism influences global chromatin structure
... Global chromatin structure regulates gene expression, DNA repair, and also affects cancer ...and chromatin architecture remain ...compacted chromatin structure. This condensed ...
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Structure and Function
... Block Grant funding for resource development activities in Minnesota declined between FYs 2000 and 2003 (from $2 to $1.5 million). In FY 2003, the largest proportion of these funds went[r] ...
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