Combinational Therapy
The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism
... DCA did not have a significant effect on the proliferation of cell lines or primary cells with mutant p53 or lacking p53, although we observed data not shown that higher DCA doses and lo[r] ...
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A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases
... As the first genetically engineered oncolytic virus (OV), oHSV-1 is an attractive vector for cancer gene therapy. oHSV-1 has a number of advantages over other OVs-derived viruses. For example, its genomic ...
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Atorvastatin as a potential anti malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum
... Synergy of QN with AVA is a promising result in malaria treatment. QN remains the first line anti-malarial drug for the treatment of complicated malaria in Europe and Africa. However, clinical failures became more fre- ...
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High Loading of Hydrophobic and Hydrophilic Agents via Small Immunostimulatory Carrier for Enhanced Tumor Penetration and Combinational Therapy
... More DiR signals were observed in the tumor core treated with DiR-loaded PGEM nanoparticles than the one treated with DiR-loaded POEG-co-PVD nanoparticles, indicating better penetrat[r] ...
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<p>Cyclodextrin-Modified CeO<sub>2</sub> Nanoparticles as a Multifunctional Nanozyme for Combinational Therapy of Psoriasis</p>
... The calculated spleen/ body weight% of the IMQ group (1.02 ± 0.26) was approxi- mately three times larger than that of the normal mouse group (0.31 ± 0.05), and the results showed that t[r] ...
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COMBINATIONAL THERAPY OF ROSUVASTATIN CALCIUM AND FENOFIBRATE AS BILAYER TABLET: A POTENTIAL APPROACH TO CONTROL HYPOLIPIDAEMIA
... methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) currently form the mainstay of lipid-regulating therapy, and are the most effective agents for reducing serum cholesterol concentrations and ...
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PUMA mediates the combinational therapy of 5-FU and NVP-BEZ235 in colon cancer
... Since the activation of Akt/mTOR pathway decreased sensitivity to chemotherapeutics as well as to irradiation (IR) [36, 37], which was activated in our system, it may decrease the sensitivity of cells to 5-FU treatment. ...
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A PROSPECTIVE DRUG UTILISATION EVALUATION OF ACUTE GASTROENTERITIS IN PEDIATRIC PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL
... the combinational therapy of Antibiotics and anti- gastric drugs was found to be in ...The combinational therapy of Antibiotics with NSAID’s was found to be in ...
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Molecular monitoring of Plasmodium falciparum super resistance to sulfadoxine–pyrimethamine in Tanzania
... artemisinin-based combinational therapy; CQ: chloroquine; SMC: seasonal malaria chemoprevention; ELISA: enzyme-linked immunosorb- ent assay; IPTi: intermittent preventive treatment of malaria in infancy; ...
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<p>Applications of Inorganic Nanomaterials in Photothermal Therapy Based on Combinational Cancer Treatment</p>
... each combinational therapy, two cancer treat- ments work independently and complementarily and the synergistic effects due to each is ...above combinational therapies, the combination with che- ...
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THE SYNERGESTIC EFFECTS OF EDTA / ANTIBACTERIAL COMBINATIONS IN KLEBSIELLA PNEUMONAE INDUCED PNEUMONIA RAT MODEL
... a combinational therapy against antioxidant enzyme activity, lipid peroxidation level, some hematological and biochemical parameters in Klebsiella pneumoniae induced nosocomial pneumonia followed by ...
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Combinational immune-cell therapy of natural killer cells and sorafenib for advanced hepatocellular carcinoma: a review
... Sorafenib which is the first FDA approved drug for treat- ment of HCC, is a multi-kinase inhibitor that can block proliferation and angiogenesis of tumor cell by inhibiting a wide range of molecular targets including ...
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Biological Modulation of Parp Inhibition in Triple Negative Breast Cancer, a Combinational Approach Implementing Multitargeted Epigenetic Therapy (Mtet) with Parp Inhibition, in Advanced Breast Cancer: A Case Study
... the therapy fails ...immune therapy and interestingly relevant to this article, epigenetic therapies ...a combinational therapy, con- sisting of PARP inhibitor and epigenetic ...epigenetic ...
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MINIMIZATION OF TERNARY COMBINATIONAL CIRCUITS - A SURVEY
... The most popular in the literature are three-valued logic, the finite-valued with more than 3 values and the infinite-valued (e.g. fuzzy logic) logics. In this paper emphasis is on the three-valued logic, which has three ...
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Algorithms for Solving Boolean Satisfiability in Combinational Circuits
... Boolean Satisfiability is a ubiquitous modeling tool in Electronic Design Automation, It finds application in test pattern generation, delay-fault testing, combinational equivalence checking and circuit delay ...
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An expert system to optimize combinational logic
... inverter conversion there variables, 2 3, and 1, signal by applying an variable finishes process 5 output resulting in 0, with gate an example rule 2 gate gate 1 which gate AND/OR constr[r] ...
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Ground Bouncing Noise Reduction in Combinational Circuits
... The comparison of the proposed technique with other ground bounce reduction technique like Tri–mode technique, stacking power technique and dynamic variation of size of sleep device have[r] ...
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Solving Satisfiability in Combinational Circuits
... As EDA evolves, researchers continue to find modeling tools to solve problems of test generation, design verification, logic, and physical synthesis, among others. One such modeling tool is Boolean satisfiability (SAT), ...
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A New Combinational Terminology for Geothermal Systems
... a combinational terminology of geological and tempera- ture-based classifications would be more ...in combinational terminology (from left to right), the class of geothermal resource’s name would be placed ...
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Fault Tolerance Techniques for Combinational Circuits
... ABSTRACT: Increasing in soft error rates, the multiple faults is needed to be considered while modeling circuit sensitivity and evaluating fault tolerance techniques. This paper proposed a design of combinational ...
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