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complement system

WIESLAB Complement system

WIESLAB Complement system

... the Complement system AP kit the wells of the microtitre strips are coated with specific activators of the alternative ...wells, complement is activated by the specific ...

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Activation of complement system in kidney after ketoprofen-induced kidney injury in sheep

Activation of complement system in kidney after ketoprofen-induced kidney injury in sheep

... to tubular injury [34,35]. It is believed that the tubular epithelium plays a critical role in the inflammatory and fibrotic changes seen in the interstitium when exposed to high concentrations of protein [36]. ...

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Increased activity of the complement system in cerebrospinal fluid of the patients with Non HIV Cryptococcal meningitis

Increased activity of the complement system in cerebrospinal fluid of the patients with Non HIV Cryptococcal meningitis

... the complement terminal pathways were activated in CSF during ...the complement ter- minal pathway results in releasing anaphylatoxins C5a, and formation of a membrane attack complex to lyse the target ...

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Expression of complement system components during aging and amyloid deposition in APP transgenic mice

Expression of complement system components during aging and amyloid deposition in APP transgenic mice

... the complement system in Alzheimer's disease pathogenesis has been postulated previously (for a summary see ...detected complement components in association with parenchymal amyloid plaques but also ...

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The role of the complement system in traumatic brain injury: a review

The role of the complement system in traumatic brain injury: a review

... the complement system plays in TBI secondary ...The complement system can have both neurotoxic effects as well as neuroprotective influences subsequent to CNS ...the complement ...

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Expression and localization of proteins of the complement system in human skin

Expression and localization of proteins of the complement system in human skin

... The complement system participates in the immune recognition of foreign antigens, many of which may penetrate the skin by physical injury or transcutaneous ...of complement components and ...

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Evaluation of Pasteurella multocida serotype B:2 resistance to immune serum and complement system

Evaluation of Pasteurella multocida serotype B:2 resistance to immune serum and complement system

... Members of gram-negative bacteria family Pasteurellaceae, include a large number of important economically human and veterinary pathogens. Organisms belonging to the family can colonize in mucosal surfaces of the ...

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A C3(H20) recycling pathway is a component of the intracellular complement system

A C3(H20) recycling pathway is a component of the intracellular complement system

... intracellular complement system (ICS) has recently been described in immune and nonimmune human ...This system can be activated in a convertase-independent manner from intracellular stores of the ...

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Activation of the complement system in patients with porphyrias after irradiation in vivo

Activation of the complement system in patients with porphyrias after irradiation in vivo

... the complement system, as assessed by diminution of the hemolytic titers of the third component of complement by 23- 57%, and of the fifth component of complement (C5) by ...

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Structural studies of factor B of the alternative pathway of the complement system

Structural studies of factor B of the alternative pathway of the complement system

... the complement system detect “targets” and bind to them, usually by mechanisms that involve the recognition of charge distribution patterns or of carbohydrate on the surface of the ...of complement ...

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Complement system and age-related macular degeneration: drugs and challenges

<p>Complement system and age-related macular degeneration: drugs and challenges</p>

... the complement cascade, presum- ably controlling the entire complement ...The complement system functions as the fi rst defense line of innate immune response, protecting human organism from ...

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New Insights of an Old Defense System: Structure, Function, and Clinical Relevance of the Complement System

New Insights of an Old Defense System: Structure, Function, and Clinical Relevance of the Complement System

... The complement system was discovered a century ago as a potent defense cascade of innate ...damage, complement reveals beneficial functions of pathogen and dan- ger defense by sensing and clearing ...

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Complement system activation contributes to the ependymal damage induced by microbial neuraminidase

Complement system activation contributes to the ependymal damage induced by microbial neuraminidase

... the complement system, and specif- ically the MAC, in ependymal destruction caused by NA, the action of this enzyme was evaluated under a situation of partial inhibition or complete blockade of MAC ...the ...

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Evolution of the initiating enzymes of the complement system

Evolution of the initiating enzymes of the complement system

... mammalian complement system, as one of the major constituents of innate immunity, plays a pivotal role in defending the body against pathogenic ...30 complement components, about one-fourth are ...

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Role of the complement system in the tumor microenvironment

Role of the complement system in the tumor microenvironment

... the complement system on ...the complement proteins C7 and FH were upregulated in liver tumor-initiating cells, and these proteins were needed to control the stemness of liver cancer cells via LSF-1 ...

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The role of the complement system in cancer

The role of the complement system in cancer

... the complement system in cancer biology is evolving, changing our approach to the therapeutic use of reagents modifying the complement ...harvesting complement-dependent cytotoxicity induced ...

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The complement system in glioblastoma multiforme

The complement system in glioblastoma multiforme

... plement system by Buchner et al. it was realized that the actions of complement are not constrained to an ef- fector mechanism of the innate immunity, but are also involved in directing the adaptive immune ...

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Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord

Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord

... of complement genes were then upregulated in DKO mice with ...of complement genes took place along with neurodegeneration in the ner- vous tissues of DKO ...the complement system, we examined ...

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The complement system is activated in synovial fluid from subjects with knee injury and from patients with osteoarthritis

The complement system is activated in synovial fluid from subjects with knee injury and from patients with osteoarthritis

... On the basis of time between injury and synovial fluid as- piration, the subjects with knee injury were stratified into a recent injury group (sampling 0–83 days, or 0–12 weeks, after injury) and an old injury group ...

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The Association of Respiratory Infection, Recurrent Hematuria, and Focal Glomerulonephritis with Activation of the Complement System in the Cold

The Association of Respiratory Infection, Recurrent Hematuria, and Focal Glomerulonephritis with Activation of the Complement System in the Cold

... activation of complement (C) in the cold requires the patient's IgA. Removal of IgA from the serum by immunoadsorption prevents activation and conversion of C3. Bactericidal and phagocytic activity is also ...

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