CXCR-4
Use of Murine CXCR-4 as a Second Receptor by Some T-Cell-Tropic Human Immunodeficiency Viruses
... mouse CXCR-4 determined functional efficiency as a second receptor for T-cell line-tropic HIV-1 ...murine CXCR-4 is the most dramatic of the sequence differ- ences in this segment, our results ...
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CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1.
... CD4, CXCR-4, and CCR-5 dependen- cies for infections by diverse primary patient (PR) and laboratory-adapted (LA) isolates of human immuno- deficiency virus type 1 ...a CXCR-4 expression ...
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A monoclonal antibody (12G5) directed against CXCR-4 inhibits infection with the dual-tropic human immunodeficiency virus type 1 isolate HIV-1(89.6) but not the T-tropic isolate HIV-1(HxB).
... U87-CD4-CXCR-4. To rule out the possibility that the re- sults with the HxB viruses and V3 chimeras in CEMx174 cells were due to their use of a different coreceptor, we tested MAb 12G5 for inhibition of ...
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Usage of the coreceptors CCR-5, CCR-3, and CXCR-4 by primary and cell line-adapted human immunodeficiency virus type 2.
... and CXCR-4, and possibly CCR-3, are the principal human immunodefi- ciency virus type 1 (HIV-1) coreceptors, apparently interacting with HIV-1 envelope, in association with ...and CXCR-4 ...
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CXCR-4 Is Expressed by Primary Macrophages and Supports CCR5-Independent Infection by Dual-Tropic but Not T-Tropic Isolates of Human Immunodeficiency Virus Type 1
... ing CXCR-4. Because these studies revealed both CXCR-4 gene expression and protein on the surface of macrophages but no CCR3 or CCR8 and inconsistent CCR2b expression, we next examined whether ...
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T-Tropic Human Immunodeficiency Virus Type 1 (HIV-1)-Derived V3 Loop Peptides Directly Bind to CXCR-4 and Inhibit T-Tropic HIV-1 Infection
... After the submission of this manuscript, an analysis of the crystal structure of an HIV-1 gp120 core glycoprotein in com- plex with CD4 and a neutralizing antibody was published (27, 49). Based on this analysis and using ...
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CD4-independent infection by human immunodeficiency virus type 2 strain ROD/B: the role of the N-terminal domain of CXCR-4 in fusion and entry.
... proteins, CXCR-4 (18) (also termed Fusin or Lestr) and CCR-5, have been shown to function as core- ceptors, together with CD4, for T-cell-line- and macrophage- tropic HIV-1 isolates, respectively (1, 13, ...
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CXCR-4 expression by circulating endothelial progenitor cells and SDF-1 serum levels are elevated in septic patients
... FITC-conjugated CXCR-4 or APC-conjugated c-Kit, APC-conjugated CXCR-2 (all R&D Systems, Wiesbaden-Nordenstadt, Germany), PE-conjugated PSGL1 (BD Biosciences, Heidelberg, Germany) or the indir- ...
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Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity.
... rat CXCR-4 from the cytomegalovirus immediate-early promoter have been described previously ...rat CXCR-4 cDNA (kindly provided by ...mouse CXCR-4 (see ...human ...
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Original Article Icariin administration is associated with enhanced homing of bone marrow-derived progenitor cells, increased levels of CXCR-4/SDF-1α homing factors, and attenuated brain injury in a rat stroke model
... The traditional Chinese herb Epimedium has been reported to possess various important pharmacological effects, such as increasing cerebral blood flow, anti-inflammatory effects, promoting nerve regeneration, improving ...
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Icariin promotes the migration of bone marrow stromal cells via the SDF-1α/HI F-1α/CXCR 4 pathway
... at 4 ° ...at 4 ° C overnight, the membranes were exposed to the cor- responding horseradish peroxidase-conjugated secondary antibodies and visualized by enhanced ...
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Interleukin 17A promotes functional activation of systemic sclerosis patient derived dermal vascular smooth muscle cells by extracellular regulated protein kinases signalling pathway
... receptor 4 (CXCR-4) and chemokine (C-C motif) ligand 20 (CCL-20) in vascular endothelial cells, resulting in endothelial inflammation in SSc ...
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2 (4 Chlorophenyl) 4 oxo 4 phenylbutanenitrile
... Data collection: CrysAlis PRO Agilent, 2013; cell refinement: CrysAlis PRO; data reduction: CrysAlis PRO; programs used to solve structure: SHELXS2013 Sheldrick, 2008; programs used to r[r] ...
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Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis
... natural killer (NK) cells [4, 5]. An increased number of CXCR3 + cells were also found in lupus nephritis and in atherosclerotic lesions secondary to systemic lupus erythe- matosus (SLE) [6, 7]. CXCR4 is a ...
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4 (4 Aminophenylsulfonyl)anilinium toluene 4 sulfonate
... of 4-(4-aminophenylsulfonyl)aniline (dapsone) with p-toluenesulfonic acid by heating together for 15 min under reflux, 1 mmol quantities of the two reagents in 50 ml of 50% ...
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4 [4 (4 Formylphenoxy)butoxy]benzaldehyde
... species 4-[6-(4-formyl-2-methoxyphen- oxy)hexyloxy]-3-methoxybenzaldehyde (Diao et ...and 4-[4-(4-formyl-2-methoxyphenoxy)butoxy]-3-methoxybenz- aldehyde (Duan & Zhang, ...
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4 [4 (4 Nitrophenyldiazenyl)phenyl]hexanenitrile
... Data collection: CAD-4 Software (Enraf–Nonius, 1989); cell refinement: CAD-4 Software; data reduction: XCAD4 (Harms & Wocadlo, 1995); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); ...
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Synchronicities 4:4
... leading to information to to guide their re-sensitize in learn to become information can be also As biologist believe it is less biological nature, do we frightening to shared with many [r] ...
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4 Aminopyridinium 4 nitrobenzoate 4 nitrobenzoic acid
... nitrobenzoic acid and 4-nitrobenzoate. In the crystal structure, the cations, anions and the neutral 4-nitrobenzoic acid molecules are linked by O—H O and N—H O hydrogen bonds, forming a two-dimensional ...
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4 Aminopyridinium 4 aminobenzenesulfonate 4 ammoniobenzenesulfonate monohydrate
... ), one 4- aminopyridinium cation and two half-molecules of water, each lying on a twofold rotation axis. The various ions and molecules in the structure are linked through N—H O, N— H N and N—H S hydrogen bonds ...
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