cyclic AMP response element
The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein.
... Tax response elements (TxREs), are located in the U3 region of the HTLV-1 LTR (30) ...A cyclic AMP response element-like sequence, TGACG, is located in the core of each repeat and is ...
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Estrogen Upregulates Cyclic AMP Response Element Modulator α Expression and Downregulates Interleukin-2 Production by Human T Lymphocytes
... the cyclic AMP response element binding (CREB) and cyclic AMP response element modu- lator (CREM) transcription ...
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Human papillomavirus type 16 E6 protein transcriptionally modulates fibronectin gene expression by induction of protein complexes binding to the cyclic AMP response element.
... Although human papillomavirus type 16 (HPV16) E6 protein has a transcription-modulatory activity for a wide variety of viral promoters, a cellular target for this activity of E6 has not yet been identified. In this ...
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A functional cyclic AMP response element plays a crucial role in neuroendocrine cell type specific expression of the secretory granule protein chromogranin A
... cAMP response element (CRE) site at -68 bp virtually abolished promoter activity specifically in neuroendocrine (PC12 chromaffin or AtT20 corticotrope) cells, with little effect on activity in control ...
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Cellular transcription factor binds to adenovirus early region promoters and to a cyclic AMP response element.
... Because we observed efficient E4 transcription in vitro that was dependent on elements within the 5'-flanking sequences, the HeLa whole-cell extract was used to detect cellular factors t[r] ...
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Original Article Distribution of phosphorylated cyclic AMP response element binding protein (p-CREB-1) in rat retina
... teins such as Bcl-2 and brain-derived neuro- trophic factor (BDNF) by a p-CREB-1-dependent mechanism [11]. In the adult hippocampus, CREB-1 phosphorylation occurs in response to a diverse array of stimuli and has ...
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Minocycline upregulates cyclic AMP response element binding protein and brain-derived neurotrophic factor in the hippocampus of cerebral ischemia rats and improves behavioral deficits
... cAMP response element binding protein (CREB) plays an important role in the mechanism of cognitive impairment and is also pivotal in the switch from short-term to long-term ...
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Identification of human T-cell lymphotropic virus type I 21-base-pair repeat-specific and glial cell-specific DNA-protein complexes.
... Competition EMS analyses with oligonucleotides containing transcription factor binding site sequences indicate the involvement of a cyclic AMP response element binding protein in the for[r] ...
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Function of the human T-cell leukemia virus type 1 21-base-pair repeats in basal transcription.
... core cyclic AMP response element (CRE) found in all three TRE1s, while the cellular transcription factor Sp1 bound the TATA-proximal TRE1 in a CRE-independent ...
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Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic target
... The cyclic AMP response element binding (CREB) protein has pleiotropic activities in physiologic processes. Due to its central position downstream of many growth signaling pathways CREB has ...
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Dangguijakyak san ameliorates memory deficits in ovariectomized mice by upregulating hippocampal estrogen synthesis
... (ERK)/cyclic-AMP response element-binding protein (CREB) signaling in long-term hippocampal memory in neurons [8–11] and synaptic protein, including synapto- physin (SYN) and postsynaptic ...
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Cyclic AMP signalling in pancreatic islets
... Expression of an AKAP (AKAP18) in clonal insulin-secreting cells (RINm5f) aug- mented GLP-1-induced insulin release, whereas expression of a mutant form in these cells was inhibitory [82]. These findings were supported ...
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Essential role for cyclic-AMP responsive element binding protein 1 (CREB) in the survival of acute lymphoblastic leukemia
... Interestingly however, within the list of downregulated genes, enzymes involved in glycolysis (GPI, ALDOC, and PKM2), TCA cycle (DLAT and IDH3A), and serine and glycine biosynthesis (PHGDH, PSAT1, and SHMT2) were among ...
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Electrical transients in the cell volume response to cyclic AMP of the tsetse fly Malpighian tubule
... Microscopic examination of the tubules bathed in Cl − Ringer revealed the lumen to be partially obliterated during the first 2 min, but distended by 10 min, after exposure to cyclic AMP. Calculation based ...
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Cyclic AMP induces a relaxation response in the bullfrog Rana catesbeiana, but nitric oxide does not
... of cyclic AMP, was used to confirm that the relaxation observed was mediated by increases in intracellular cyclic AMP ...by cyclic AMP, cyclic AMP was used to ...
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Kinetic Analysis of the Antidiuretic Action of Vasopressin and Adenosine 3′,5′ Monophosphate
... maximal response to saturating concentrations of cyclic AMP and the decay of the response to about 80% of the peak value, the addition of saturating quantities of vasopressin to the sero[r] ...
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Stimulation by Alcohols of Cyclic AMP Metabolism in Human Leukocytes: POSSIBLE ROLE OF CYCLIC AMP IN THE ANTI INFLAMMATORY EFFECTS OF ETHANOL
... concentrations as low as 80 mg/dl produced significant elevations in lymphocyte cAMP. Significant but less marked augmentation of cAMP in response to alcohols was observed in human platelets, human granulocytes, ...
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Insulin release and cyclic AMP accumulation in response to glucose in pancreatic islets of fed and starved rats
... (cyclic AMP) responses to glucose were compared in pancreatic islets of fed and starved ...3H cyclic AMP in islets prelabeled with 3H-2-adenine was less in islets of 48 h starved than fed ...
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Chemotactic responses of Dictyostelium discoideum amoebae to a cyclic AMP concentration gradient: evidence to support a spatial mechanism for sensing cyclic AMP
... All the amoebae in the cell chamber are categorized into two groups: (1) ascending amoebae, which move in the direction of a 180 ° sector facing towards the cAMP-containing test chamber; and (2) descending amoebae, which ...
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Cyclic AMP-responsive element-dependent activation of Epstein-Barr virus zebra promoter by human herpesvirus 6.
... Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6) are pathogenic herpesviruses that are distributed worldwide. EBV infection of human B lymphocytes results in the immor- talization of these cells, with the virus ...
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