Development and evaluation of single nucleotide polymorphism
Evaluation of single nucleotide polymorphism imputation using random forests
... BMC Proceedings Proceedings Evaluation of single nucleotide polymorphism imputation using random forests Daniel F Schwarz, Silke Szymczak, Andreas Ziegler and Inke R K?nig* Address Institut f?r Medizi[.] ...
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Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers
... tumour development and failure to respond to treatment ...at nucleotide 309 within the promoter region of MDM2, which increases the affinity of the transcriptional activator Sp1 and results in higher levels ...
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Development of Single Nucleotide Polymorphism Markers for the Wheat Curl Mite Resistance Gene Cmc4
... NBS, nucleotide binding site; PCR, polymerase chain reaction; QTL, quantitative trait locus; RFLP, restriction fragment length polymorphism; RIL, recombinant inbred line; SNP, single ...
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Development and Evaluation of a Novel Single Nucleotide Polymorphism Real Time PCR Assay for Rapid Detection of Fluoroquinolone Resistant Mycoplasma bovis
... 2. Be ´be ´ar, C. M., and S. Pereyre. 2005. Mechanisms of drug resistance in Mycoplasma pneumoniae. Curr. Drug Targets Infect. Disord. 5:263–271. 3. Beeton, M. L., V. J. Chalker, S. Kotecha, and O. B. Spiller. 2009. ...
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Development of a single nucleotide polymorphism array for population genomic studies in four European pine species
... The moderate conversion rate for the pine array was probably due to a combination of factors. The use of transcriptome sequences for SNP discovery, which aimed to identify markers in coding re- gions, may have resulted ...
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Evaluation of ERAP1 Gene Single Nucleotide Polymorphism in Impressing the Inflammatory Cytokine Profile of Ankylosing Spondylitis Patients
... rs27044 polymorphism with the risk of AS in Iranian population in 140 AS cases and 140 healthy subjects and tried to discover if these variants affect the inflammatory profile of AS ...
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SNP-E: A New Method For Multiple Sequence Alignments Analysis And Accurate Single Nucleotide Polymorphism Evaluation
... of single nucleotide polymorphisms (SNPs) in multiple sequence alignments (MSA) involves looking across MSA and identifying base discrepancies (Wegrzyn et ...calling single-nucleotide poly- ...
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Development and validation of a novel single nucleotide polymorphism (SNP) panel for genetic analysis of Blastomyces spp and association analysis
... Our SNP assay did not resolve the same level of gen- etic variability within Blastomyces spp. isolates as compared to our microsatellite assay. This is most cer- tainly due to the higher mutation rate of microsatellite ...
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Development of a New A –Genome-Specific Single Nucleotide Polymorphism Marker Set for the Molecular Characterization of Wheat– Introgression Lines
... polymorphism (SNP) markers suitable for rapid identification of T. monococcum chromatin in a wheat background. We identified 1247 polymorphic SNPs between T. monococcum and wheat. We identified 191 markers across ...
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A General Overview of Detection Methods for Single Nucleotide Polymorphism
... reference genome sequence [8]. Through sequence comparison, we can find a lot of biological information related to the genetic evolution of organisms. The main idea of two-sequence alignment is based on the similarity ...
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Association between neonatal resuscitation and a single nucleotide polymorphism rs1835740
... We hypothesise that these functional SNPs affecting glutamatergic signalling, homeostasis and cell survival in the CNS may influence infants’ susceptibility to the birth process and subsequent development of ...
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A High-Density Single Nucleotide Polymorphism Map for Neurospora crassa
... of single nucleotide polymorphisms (SNPs) between the reference Neurospora crassa strain Oak Ridge and the Mauriceville strain (FGSC 2555), of sufficient density to allow fine mapping of most ...the ...
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Methods for demographic inference from single-nucleotide polymorphism data
... the evaluation of the likelihood function, p(x|φ), and when this function is computationally unattainable for example, in the pres- ence of complex missing data such as the genealogy of a ...
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A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer
... In our results, the data also suggested the expression of SET8 has a significant association with prognosis of breast cancer. SET8 is known as the sole methyltransferase for H4K20me1, which usually associates with the ...
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Genome-Wide Single-Nucleotide Polymorphism Map for Candida albicans
... Single-nucleotide polymorphisms (SNPs) are essential tools for studying a variety of organismal properties and processes, such as recombination, chromosomal dynamics, and genome rearrangement. This paper ...
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Single-Nucleotide-Polymorphism-Based Association Mapping of Dog Stereotypes
... Ideally, two types of data are required for across-breed association analysis: (1) a common set of well-distributed, highly informative SNPs that characterize the entire ge- nome for each of many breeds and (2) a careful ...
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Functional Characterization of the OPRM1 A118G Single Nucleotide Polymorphism in Mice
... the development of tolerance and dependence has made it difficult to adequately prescribe these ...common single nucleotide polymorphism (SNP), A118G, in the µ -opioid receptor gene can affect ...
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Association of Osteopontin Gene Single Nucleotide Polymorphism with Systemic Lupus Erythematosus.
... a single nucleotide polymorphism (SNP) at position 9250 (C to T) in exon 7 of the osteopontin (OPN) gene is highly associated with the susceptibility to systemic lupus erythematosus (SLE) among ...
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Colorimetric Assays for the detection of single nucleotide polymorphism based on plasmonic nanoparticles
... The above-mentioned limitations have prompted the development of new methods for the harvesting of cancer biomarkers in a simpler and more convenient way, compared to tissue biopsy. The science of non-invasive ...
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Assessment of Linkage Disequilibrium in Potato Genome With Single Nucleotide Polymorphism Markers
... high polymorphism in potato may be explained by mating ...Similarly, nucleotide vari- ation was substantially reduced in self-pollinating Leav- enworthia species (L iu et ...of evaluation of RAPD ...
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