DNA-BINDING ACTIVITY
Immunoglobulin classes of DNA binding activity in serum and skin in systemic lupus erythematosus
... native DNA binding activity (nDNA-BA) in the serum and subepidermal immunoglobulin deposits were studied to determine the relationship of the immunoglobulin (Ig) class distribution of serum nDNA-BA ...
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Role of Single-Stranded DNA Binding Activity of T Antigen in Simian Virus 40 DNA Replication
... single-stranded DNA binding domain of large T antigen to amino acid residues 259 to ...this binding activity, a series of single-point substitutions were introduced in this domain, and the ...
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Progesterone Induces NFκB DNA Binding Activity through a PI3K/Akt-Dependent Pathway in MCF-7 Breast Cancer Cells
... NFκB binding site. As illustrated in Fig. 2A, a weak specific NFκB-DNA complex was observed in untreated cells, however treatment with PG significantly increased the DNA binding ...
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Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42.
... the DNA binding activity of UL42 appears to be required for HSV DNA replication, one approach to the design of an anti-HSV drug could be the interruption of the UL42-DNA ...the ...
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MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain
... directly binding to the ...to DNA, resulting in incomplete inhibition of STAT3 ...and DNA-binding activity of STAT3 in other cancer cell lines including colon and ovarian cancer ...the ...
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DNA-binding activity of papillomavirus proteins.
... Further characterization of the DNA-binding activity of these E2 proteins at 50 mM NaCl, pH 7.0, demonstrated that all [32P]-labeled DNAs, including pBR322, were bound with equal efficie[r] ...
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Induction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation.
... These data strongly suggest that specific cellular ElA-binding proteins are involved in the induction of AP-1 DNA-binding activity and c-fos mRNA by the synergistic action of the 243R EI[r] ...
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Regulation of Sp2 DNA-Binding Activity and trans-Activation
... Sp2 DNA-binding activity, I attempted to identify the molecular weight of Sp2 kinase(s) by conducting in vitro kinase assays using mammalian cell extracts that had been fractionated via size ...
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Purification and characterization of the DNA-binding activity of the Epstein-Barr virus DNA polymerase accessory protein BMRF1 gene products, as expressed in insect cells by using the baculovirus system.
... 3 0022-538X/93/031681-07$02.00/0 Copyright © 1993, American Society for Microbiology Purification and Characterization of the DNA-Binding Activity of the Epstein-Barr Virus DNA Polymeras[r] ...
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DNA Binding Activity of the Herpes Simplex Virus Type 1 Origin Binding Protein, UL9, Can Be Modulated by Sequences in the N Terminus: Correlation between Transdominance and DNA Binding
... origin binding protein of herpes simplex virus type 1, is a member of the SF2 family of ...viral DNA and plasmids expressing either full-length UL9 or the C-terminal DNA binding domain alone ...
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Phosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen.
... 888 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Proteolytic fragments of simian virus 40 tumor T antigen and T antigen that was dephosphorylated with alkaline phosp[r] ...
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DNA-binding activity associated with the v-myb oncogene product is not sufficient for transformation.
... Ni, Primary nuclear transport signal; N2, secondary signal which is required for complete nuclear localization in the presence of Ni; DNA-B, domain required for associated DNA-binding ac[r] ...
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A DNA-binding activity in BPV initiator protein E1 required for melting duplex ori DNA but not processive helicase activity initiated on partially single-stranded DNA
... two binding sites in ori by the viral transcription factor E2 ...the DNA (16). The sequence-specific DNA-binding domain (DBD) of E1 performs an essential function in this process, targeting E1 ...
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STUDIES ON THE DNA BINDING ACTIVITY OF SCHIFF BASE DERIVED COMPOUNDS
... the DNA cleavage activity of some newly synthesized Metal based Ruthenium and Copper complex Schiff base compounds using calf thymus DNA by gel electrophoresis ...
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SUMO 1 possesses DNA binding activity
... same DNA substrate containing a central G:U mis- match which had been used in the experiments leading to the hypothesis of SUMO-1 DNA binding (5'-GCTTC- GAGTACCUGTGGAACCTATC-3') we observe chemi- cal ...
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N-ethylmaleimide inhibition of the DNA-binding activity of the herpes simplex virus type 1 major DNA-binding protein.
... To determine whether this was indeed the case, equilibrium dialysis experiments with ICP8 and [32P]dT1o were done in the presence and absence of NEM as described DISCUSSION The results p[r] ...
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The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA.
... Furthermore, since no induction of binding activity was observed on a single-site probe data not shown, we conclude that the activation is not simply an induction of DNA-binding activity[r] ...
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A bovine papillomavirus E1-related protein binds specifically to bovine papillomavirus DNA.
... The bacterially expressed RecA-El protein exhibited sequence-specific DNA binding activity; strong binding to the region from nucleotides 7819 to 93 on the BPV genome designated region A[r] ...
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DNA Binding Studies of Ni(Ii) Complex of (E-2-Chloro-N-(3-Hydroxy-5-Hydroxymethyl)-2-Methylpyridin-4-Yl)Methylene) Acetohydrazide
... 4yl)methylene) acetohydrazide, a derivative of pyridoxal was synthesized by conventional method by treating Pyridoxal hydrochloride with Chloroacetic hydrazide. Ni (II) metal complex was synthesized and characterized ...
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Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity.pdf
... We therefore conclude that the MAD-3 translation product specifically inhibits NF-KB DNA-binding activity and does not inhibit the DNA-binding activity of KBFl , ma[r] ...
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