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DNA Cleavage

Studies on dna cleavage, antimicrobial screening and anticancer activity  of zr(iv) and th(iv) metal complexes of dfmpm and glycine

Studies on dna cleavage, antimicrobial screening and anticancer activity of zr(iv) and th(iv) metal complexes of dfmpm and glycine

... The Zr(IV) and Th(IV) Schiff base complexs with di--formylmethoxybis(3- pentadecenylphenyl)methane (DFMPM) and glycine were synthesized and characterized by elemental analysis, conductivity measurements, electronic, IR, ...

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Synthesis, Characterization, Antibacterial Activity and DNA cleavage studies of Schiff base Co(II)

Synthesis, Characterization, Antibacterial Activity and DNA cleavage studies of Schiff base Co(II)

... The authors express their sincere thanks to the management, PG and Research department of Chemistry C. Abdul Hakeem College, Melvisharam. We also thank SAIF, IIT Kanpur for providing FTIR, TGA-DTA analyzer, Mass, SAIF, ...

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Biological activity, Spectroscopic and DNA Cleavage of Binuclear Schiff Base Complexes

Biological activity, Spectroscopic and DNA Cleavage of Binuclear Schiff Base Complexes

... DNA cleavage is controlled by relaxation of supercoiled circular conformation of pUC18 DNA to nicked circular conformation and linear ...plasmid DNA is conducted by electrophoresis, the ...

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DNA Cleavage and Antimicrobial Activity Studies of Some New Sulfadoxine Complexes

DNA Cleavage and Antimicrobial Activity Studies of Some New Sulfadoxine Complexes

... 4-Amino-N (5,6-dimethoxy-4-pyrimidinyl)benzene sulfonamide, (SDX) sulfadoxine was reacted with Ag and Pt. The products were characterized by elemental (CHN) analysis, FTIR, conductance measurements, electronic spectra, ...

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DNA Cleavage Activity of Copper (II) Complexes of Some Phosphonates

DNA Cleavage Activity of Copper (II) Complexes of Some Phosphonates

... towards DNA cleavage were ...showed DNA cleavage ...towards DNA cleavage. Index Terms- phosphonate; spectroscopic studies; DNA cleavage ...

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In vitro anti microbial and DNA cleavage studies of benzimidazole derivatives

In vitro anti microbial and DNA cleavage studies of benzimidazole derivatives

... In conclusion, we have screened for in vitro anti-bacterial and anti-fungal activities against the several microorganisms. Some of the synthesized compounds which contain chloro, bromo derivatives showed excellent ...

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Synthesis, structural chararcterization, antimicrobial activity and  dna cleavage of transition metal (ii) complexes derived from 5 bromo 3 hydrazonoindolin 2 one, 3 ((2 aminoethyl) amino) quinoxalin 2(1h) one  and 2,2 dimethyl 1,3 dioxane 4,6 dione

Synthesis, structural chararcterization, antimicrobial activity and dna cleavage of transition metal (ii) complexes derived from 5 bromo 3 hydrazonoindolin 2 one, 3 ((2 aminoethyl) amino) quinoxalin 2(1h) one and 2,2 dimethyl 1,3 dioxane 4,6 dione

... potency. DNA cleavage studies have also been carried out on Calf-thymus DNA and it is observed that these Co(II), Ni(II), Cu(II), Zn(II), Cd(II) shows complete DNA cleavage activity ...

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Synthesis, Characterization and Antibacterial Activity and DNA cleavage Studies of tetra dentate Schiff bases and their Zn (II) Complexes

Synthesis, Characterization and Antibacterial Activity and DNA cleavage Studies of tetra dentate Schiff bases and their Zn (II) Complexes

... The Zn (II) complexes are acquired from the various Schiff base ligands and characterized by spectral and analytical data. The results shown that all ligands are coordinated in a tetra dentate fashion to the metal ion ...

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The construction and activity of a cerium (III) complex in DNA hydrolytic cleavage

The construction and activity of a cerium (III) complex in DNA hydrolytic cleavage

... with DNA is a mode of electrostatic binding through phosphodiester linkages of ...DNA. DNA hydrolytic cleavage usually proceeded via nucleophilic substitution and the hydrolytic mechanism of ...

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Cleavage of Mispaired Heteroduplex DNA Substrates by Numerous Restriction Enzymes

Cleavage of Mispaired Heteroduplex DNA Substrates by Numerous Restriction Enzymes

... heteroduplex cleavage. We examined the effect of glycerol on cleavage of several single nucleotide mismatch heteroduplex ...enhance cleavage of non-cognate substrate cleavage by some ...

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A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex.

A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex.

... FeBABE-DNA cleavage assay in PICs using nuclear extract containing ...Rad25 cleavage fragments were visualized by Western blotting with anti-Flag ...specific cleavage fragments are indicated ...

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Antibacterial Activity, DNA Binding and Cleavage Studies of Mixed Ligand Complexes of Copper (II) with Pyridoxal Semicarbazone and Dipeptides

Antibacterial Activity, DNA Binding and Cleavage Studies of Mixed Ligand Complexes of Copper (II) with Pyridoxal Semicarbazone and Dipeptides

... the DNA cleavage ability of the metal complexes on supercoiled pBR 322 ...plasmid DNA is converted from supercoiled DNA (Form I) to nicked circular (Form II) and linear forms (Form ...plasmid ...

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Identification, Subviral Localization, and Functional Characterization of the Pseudorabies Virus UL17 Protein

Identification, Subviral Localization, and Functional Characterization of the Pseudorabies Virus UL17 Protein

... on DNA-filled C-capsids it was located in the ...that cleavage of viral DNA into unit-length genomes was inhibited in the absence of ...cells, DNA-containing capsids were not detected, while ...

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Site specific cleavage of genomic DNA mediated by triple helix formation

Site specific cleavage of genomic DNA mediated by triple helix formation

... This thesis describes the application of oligonucleotide directed triple helix formation to bind unique target sites in bacteriophage A, yeast, and human genomic DNA.. Cleavage at[r] ...

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An alternative novel tool for DNA editing without target sequence limitation: the structure guided nuclease

An alternative novel tool for DNA editing without target sequence limitation: the structure guided nuclease

... a DNA cleavage domain, as re- ported for Tst I and Bmr I ...different DNA sequences to a cleav- age domain of a desired restriction ...target DNA sequences and the Fok I cleavage domain ...

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Constructing Empirical Likelihood Confidence Intervals for Medical Cost Data with Censored Observations

Constructing Empirical Likelihood Confidence Intervals for Medical Cost Data with Censored Observations

... genomic DNA at a site known as ...the DNA cleavage activity of HK97 ...enhanced cleavage of a cos site in an engineered DNA substrate by terminase in the presence of gp74 protein ...of ...

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Isolation and restriction endonuclease cleavage of Anaplasma marginale DNA in situ in agarose

Isolation and restriction endonuclease cleavage of Anaplasma marginale DNA in situ in agarose

... Bacterial restriction endonucleases were used to produce DNA cleavage patterns that could be useful as tools to study the relatedness among Anaplasma marginale isolates.. Bovine erythroc[r] ...

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Cleavage map of BK virus DNA with restriction endonucleases MboI and HaeIII.

Cleavage map of BK virus DNA with restriction endonucleases MboI and HaeIII.

... When the three 5'- HindIII site, with HaeIII confirmed the above terminally 32P-labeled HindIII-C fragments in- finding that HaeIII-E, at map positions 0.64 to cluding Ca, Cb, and Cc wer[r] ...

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Altered restriction endonuclease cleavage pattern of simian virus 40 DNA.

Altered restriction endonuclease cleavage pattern of simian virus 40 DNA.

... Several revertants isolated from tsB204 and tsC219 displayed identical restriction patterns to those of their parental ts mutants, suggesting that the altered nucleotide sequences on the[r] ...

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Herpes Simplex Virus 1 Small Capsomere-Interacting Protein VP26 Regulates Nucleocapsid Maturation

Herpes Simplex Virus 1 Small Capsomere-Interacting Protein VP26 Regulates Nucleocapsid Maturation

... on cleavage of replicated HSV-1 DNA concatemers, (ii) impaired packaging of viral DNA genomes, and (iii) accumulated type A capsids and reduced type C capsid formation in the nuclei of infected cells ...

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