DNA replication and cell cycle
Identification of a panel of MYC and Tip60 co-regulated genes functioning primarily in cell cycle and DNA replication
... To further explore the function of MYC association with the NuA4 complex in cancer, we examined effects of shRNA-mediated knockdown of MYC and the Tip60 component of the NuA4 complex on gene expression in MD-MB231 human ...
13
Checks and Balances?: DNA replication and the cell cycle in Plasmodium
... of cell cycle regulation, checkpoints and repair mechanisms in ...or DNA repair. There may also be scope for drugs that target the cell cycle itself, since components such as the ...
32
Cell cycle regulated transcription associates with DNA replication timing in yeast and human
... Eukaryotic DNA replication follows a specific temporal program, with some genomic regions consistently replicating earlier than others, yet what determines this program is largely ...between ...
9
Human Parvovirus B19 DNA Replication Induces a DNA Damage Response That Is Dispensable for Cell Cycle Arrest at Phase G2/M
... how replication of the ssDNA genome of autonomous parvovirus induces a DDR during virus ...of cell cycle progression, symbolized by arrest at the S or G 2 /M phase checkpoint, is a classic strategy ...
11
DNA hypomethylation induces a DNA replication associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos
... hemimethylated DNA during replication and is essential for maintaining DNA ...global DNA hypomethylation and display embryonic defects, including a small liver, and they die as ...undergoing ...
12
Simian Virus 40 Activates ATR-Δp53 Signaling To Override Cell Cycle and DNA Replication Control
... alters cell cycle regulation by Chk1-medi- ated inhibition of the mitosis-promoting factor (MPF) (37), endoreplication was observed only in infected cells that were able to downregulate AK activity, ...
21
REVIEW ARTICLE DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts
... the cell cycle is divided into two phases, interphase and mitosis ...the cell cycle : in late G1, called Start in yeast or the Restriction point in mammals, in late G2 and just prior to ...
12
Minichromosome Maintenance Proteins Cooperate with LANA during the G1/S Phase of the Cell Cycle To Support Viral DNA Replication
... latent DNA replication is essential for efficient main- tenance of KSHV episomes in the ...for replication, which occurs in synchrony with the cellular ...cellular replication complex. We ...
24
Cell cycle synchronisation of Trypanosoma brucei by centrifugal counter flow elutriation reveals the timing of nuclear and kinetoplast DNA replication
... G1 cell cycle synchronised populations of both the procyclic and bloodstream form stages of Trypanosoma brucei that yields viable and proliferative ...uniform DNA content, narrow size distribution, ...
10
NOVEL GENOME-SCALE CORRELATION BETWEEN DNA REPLICATION AND RNA TRANSCRIPTION DURING THE CELL CYCLE IN YEAST IS PREDICTED BY DATA-DRIVEN MODELS
... four DNA replication initiation proteins onto a state of transcription minima during G1, predicted by both the SVD and GSVD data-driven models, and supported by the most probable associations by ORF ...
6
Checks and balances? DNA replication and the cell cycle in Plasmodium
... unusual cell cycles of Plasmodium, which may present a rich source of novel drug targets as well as a topic of fundamental biological ...of replication including schizogony and ...
13
The temperature dependence of cell cycle parameters and chromosonal DNA replication in tissue cultures of xenopus laevis
... Dll' replication proceeds bidirectionally, the tails being the outcome of replication which occurred while cells used up their pools of precursors which had earlier been ciiarged with K-TdH frcaa the ...
141
STRUCTURE OF INTERPHASE NUCLEI IN RELATION TO THE CELL CYCLE. Chromatin Organization in Mouse L Cells Temperature-Sensitive for DNA Replication
... STRUCTURE OF INTERPHASE NUCLEI IN RELATION TO THE CELL CYCLE Chromatin Organization in Mouse L Cells Temperature Sensitive for D N A Replication From the Department of Biology,ELBA, Carleton Universit[.] ...
18
Relationship Between Replication of Simian Virus 40 DNA and Specific Events of the Host Cell Cycle
... Contrary to what was observed with cells infected during S or G2, onset of viral DNA replication in these cells was not postponed until the next cell cycle, but occurred between the hour[r] ...
9
DNA Content Measurement for DNA Ploidy and Cell Cycle Analysis
... of DNA content ...of DNA plays a role in DNA stainability is the S phase of the cell ...Namely, replication of the DNA associated with heterochromatin which is rich in AT occurs ...
24
Choreography of the Mycobacterium Replication Machinery during the Cell Cycle
... bacterial cell cycle processes, particularly chromo- some replication and segregation (1, ...of replication dynamics in single bacterial cells in real ...multiprotein replication ...
12
Host DNA Damage Response Factors Localize to Merkel Cell Polyomavirus DNA Replication Sites To Support Efficient Viral DNA Replication
... and/or cell cycle effects on C33A cells that could affect MCPyV DNA replication, we performed siRNA knockdown of ATR and/or ATM to see if we could recapitulate observations with the DDR ...
13
Herpesvirus Lytic Replication and the Cell Cycle: Arresting New Developments
... small DNA tumor viruses such as simian virus 40 (SV40) and papilloma- virus interact with cell cycle control pathways during lytic rep- lication in a way that promotes entry into the S phase of the ...
7
Human Papillomavirus DNA Replication Compartments in a Transient DNA Replication System
... host replication machinery in the viral replication ...host replication sites at a certain stage(s) of the cell ...host DNA replication is largely completed and the number of ...
9
DNA Replication and Repair
... damaged DNA throughout the cell ...in DNA during replication. BER is initiated by DNA glycosylases, which recognize and remove specific damaged or inappropriate bases, forming AP ...
13