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DNA replication and repair

DNA Replication and Repair

DNA Replication and Repair

... – DNA Replication and Repair - 18 February 2010 Page 8 purine residues per genome per generation) is too high in these species to be repaired by normal repair machinery, hence a possibility of ...

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DNA Replication in Repair

DNA Replication in Repair

... of DNA damage from anthropogenic and naturally occurring external and endogenous sources, yet DNA provides the blueprint for all other cellular ...molecules, DNA is not turned over in a cycle of ...

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DNA replication roadblocks caused by Cascade Interference complexes are alleviated by RecG DNA repair helicase.

DNA replication roadblocks caused by Cascade Interference complexes are alleviated by RecG DNA repair helicase.

... invader DNA. Recognition of invader DNA in Cascade catalysed R-loops provokes DNA capture and its subsequent integration into CRISPR loci by Cas1 and ...Cas2. DNA capture processes are unclear ...

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DNA replication roadblocks caused by Cascade Interference complexes are alleviated by RecG DNA repair helicase.

DNA replication roadblocks caused by Cascade Interference complexes are alleviated by RecG DNA repair helicase.

... invader DNA. Recognition of invader DNA in Cascade catalysed R-loops provokes DNA capture and its subsequent integration into CRISPR loci by Cas1 and ...Cas2. DNA capture processes are unclear ...

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DNA replication roadblocks caused by Cascade Interference complexes are alleviated by RecG DNA repair helicase

DNA replication roadblocks caused by Cascade Interference complexes are alleviated by RecG DNA repair helicase

... invader DNA. Recognition of invader DNA in Cascade catalysed R-loops provokes DNA capture and its subsequent integration into CRISPR loci by Cas1 and ...Cas2. DNA capture processes are unclear ...

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Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans

Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans

... DNA replication. However, mutations that arise through errors in replication from environmental stresses are biologically important since they provide variations upon which selection can ...

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A Requirement for Recombinational Repair in Saccharomyces cerevisiae Is Caused by DNA Replication Defects of mec1 Mutants

A Requirement for Recombinational Repair in Saccharomyces cerevisiae Is Caused by DNA Replication Defects of mec1 Mutants

... single-stranded DNA synthesis intermediates, suggesting that Mec1p is required for the normal progression of DNA ...of DNA synthesis intermediates and the requirement for Rad52p in mec1-srf mutants, ...

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Proteomics of Herpes Simplex Virus Replication Compartments: Association of Cellular DNA Replication, Repair, Recombination, and Chromatin Remodeling Proteins with ICP8

Proteomics of Herpes Simplex Virus Replication Compartments: Association of Cellular DNA Replication, Repair, Recombination, and Chromatin Remodeling Proteins with ICP8

... single-stranded DNA-binding ...(i) DNA replication or damage repair, including RPA and MSH6; (ii) nonhomologous and homologous recombination, including the catalytic subunit of the ...

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SURVEY AND SUMMARY DNA polymerase in DNA replication and repair

SURVEY AND SUMMARY DNA polymerase in DNA replication and repair

... ing repair choice to either pol ␨ synthesis or the ‘error- free’ template switching when the replisome runs into trou- ...of replication stress, and that pol ␨ synthesis is an important but muta- genic ...

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Redox Signaling in Eukaryotic DNA Replication and Repair

Redox Signaling in Eukaryotic DNA Replication and Repair

... form in the solution; this indicates that the reference tip is in contact with the electrode solution. This is especially important in the anaerobic chamber, where vision of the setup is limited. Cyclic voltammetry scans ...

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Elucidating the Role of [4Fe4S] Clusters in DNA Replication and Repair Proteins

Elucidating the Role of [4Fe4S] Clusters in DNA Replication and Repair Proteins

... for DNA demonstrate that large potential shifts are observable on PGE even under conditions where full DNA binding is ...study DNA-binding, the DNA-free EndoIII mutants were studied under ...

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DNA replication and repair kinetics of Alu, LINE-1 and satellite III genomic repetitive elements

DNA replication and repair kinetics of Alu, LINE-1 and satellite III genomic repetitive elements

... Previous studies employing genome-wide approaches showed a correlation between early replicating regions and enrichment for the interspersed Alu elements, while Fig. 4 DNA repair kinetics of repetitive ...

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Central Dogma. Lecture 10. Discussing DNA replication. DNA Replication. DNA mutation and repair. Transcription

Central Dogma. Lecture 10. Discussing DNA replication. DNA Replication. DNA mutation and repair. Transcription

... Synthesis occurs in 5’ - 3’ direction Specificity of which base adds depends on base pairing Specificity of which base adds depends on base pairing with template strand ( strands are com[r] ...

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The role of ChlR1 in DNA replication, DNA damage repair and cohesion establishment

The role of ChlR1 in DNA replication, DNA damage repair and cohesion establishment

... in replication fork progression and depletion of ChlR1 results in inefficient replication, I hypothesised that ChlR1 is a member of the replication ...the replication machinery then it is ...

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The Large Subunit of Replication Factor C (Rfclp/Cdc44p) Is Required for DNA Replication and DNA Repair in Saccharomyces cerevisiae

The Large Subunit of Replication Factor C (Rfclp/Cdc44p) Is Required for DNA Replication and DNA Repair in Saccharomyces cerevisiae

... induced single-stranded DNA breaks at the restrictive temperature is consistent with the hypothesis that Cdc44p plays a role in the DNA excision repair pathway.. DISCUSS[r] ...

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Ploidy Dictates Repair Pathway Choice under DNA Replication Stress

Ploidy Dictates Repair Pathway Choice under DNA Replication Stress

... to replication stress presented by a defective minichromosome maintenance (MCM) helicase allele in ...causes replication stress in both haploid and diploid yeast, only diploid mutants exhibit G2/M delay, ...

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Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication

Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication

... Obviously, RPA1 is known in yeasts and animals as a component of the single-stranded binding protein required for ‘normal’ genome replication. In contrast to the ACE group, we present here evidence that suggest ...

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Repair of Double-Strand Breaks in Bacteriophage T4 by a Mechanism That Involves Extensive DNA Replication

Repair of Double-Strand Breaks in Bacteriophage T4 by a Mechanism That Involves Extensive DNA Replication

... First, the dsb induces a repair reaction that is directly coupled to extensive plasmid replication; the repaired/replicated product is in the form of long plasmid concatemers.. Seco[r] ...

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In Vivo Analysis Reveals That the Interdomain Region of the Yeast Proliferating Cell Nuclear Antigen Is Important for DNA Replication and DNA Repair

In Vivo Analysis Reveals That the Interdomain Region of the Yeast Proliferating Cell Nuclear Antigen Is Important for DNA Replication and DNA Repair

... RAD9 checkpoint: The slowing of DNA synthesis ob- served in pol?0 mutants in the absence of MMS at the restrictive temperature suggests that pol?0 mutants may undergo cel[r] ...

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Mismatch Repair Processing of DNA Damage Causes Replication Stress

Mismatch Repair Processing of DNA Damage Causes Replication Stress

... of replication factors to complete and minimize the effects on global DNA replication ...4-1). Replication patterns observed in synchronized HeLa cells elude to this signaling mediated ...

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