fragile sites
First molecular-cytogenetic characterization of Fanconi anemia fragile sites in primary lymphocytes of FA-D2 patients in different stages of the disease
... Results: We found that chromosomal breakpoints co-localize on the molecular level with common fragile sites, whereas their distribution pattern depends on the severity of the disease. Telomere quantitative ...
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Dynamics of 45S rDNA sites in the cell cycle: fragile sites and chromosomal stability in Lolium and Festuca.
... rDNA sites in Lolium and Festuca detected by the high chromatin decondensation during the cell cycle is supported by a recent review by Dvořáčková et ...45S fragile sites in Lolium species have high ...
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Predominance of constitutional chromosomal rearrangements in human chromosomal fragile sites
... Chromosomal fragile sites (CFSs) are loci or regions susceptible to spontaneous or induced occurrence of gaps, breaks and ...mapped fragile sites to chromosomal bands and di- vided the 23 ...
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The Expression of Folate Sensitive Fragile Sites in Patients with Bipolar Disorder
... The fragile sites (FSs) are a very interesting subject for the study of clinical ...evaluate fragile sites seen in patients with bipolar disorder and find a correlation between some ...
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Fragile Sites on Chromosomes
... An unmapped avenue is treatment of fragile X males to prevent mental retardation. In a 10-year-[r] ...
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Genome reorganization in different cancer types: detection of cancer specific breakpoint regions
... adenocarcinoma, breast cancer and metastatic melanoma) and from non-malignant control samples. We calculated segmental copy number variations as well as breakpoint regions. Some of these regions were not randomly ...
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Molecular characterization of FRAXB and comparative common fragile site instability in cancer cells
... common fragile site under a variety of conditions (Glover, ...these fragile sites correlates with the frequency at which these fragile sites are generally expressed on metaphase ...
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Maintaining the unmethylated state
... of fragile sites by replication stress and carcinogen action could result in global ...of fragile sites at low concentration [127] is consistent with the idea that DNMT3B is knocked out at low ...
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Adenovirus Type 12-Induced Fragility of the Human RNU2 Locus Requires p53 Function
... chromosomal fragile sites corresponding to the U1 small nuclear RNA (snRNA) genes (the RNU1 locus), the U2 snRNA genes (RNU2), the U1 snRNA pseu- dogenes (PSU1), and the 5S rRNA genes ...PSU1 fragile ...
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Overlooked: Extrachromosomal DNA and Their Possible Impact on Whole Genome Sequencing
... FRA7G extends over a broad region: coincidence of human endogenous retroviral sequences (HERV-H) and small polydispersed circular DNAs (spcDNA) and fragile sites. Wildschutte JH, Wi[r] ...
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Targeting fragile X
... With a prevalence of 1 in 5,000, fragile X syndrome is the most common form of hereditary mental retardation [1]. Patients suffer from mild to severe mental retardation, mild facial dismorphologies and ...
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FORWARD: A Registry and Longitudinal Clinical Database to Study Fragile X Syndrome
... The participants enrolled in the FORWARD longitudinal database are a subset of those in the FORWARD registry, because only those who have been diagnosed with the full mutation and who attend a fragile X clinic are ...
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Fragile X Syndrome
... FXS was first diagnosed showing fragility at the distal end of the X chromosome at the Xq27.3 locus. Better understanding of FXS and more accurate diagnosis was achieved when the gene for FXS was identified. The gene, ...
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Catalan fragile words
... strongly fragile words that were defined in [4] in the context of automata groups, more precisely about the possibility of generating free groups by means of ...10]). Fragile words appear in the context of ...
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DATA CONFIDENTIALITY IN THE WORLD OF CLOUD
... a fragile scheme for relational database integrity check but Iqbal, Rauf partitioned the R logically into three groups then generates self-constructing fragile watermark information from each ...a ...
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ASFMR1 splice variant
... region fragile X mental retardation 1 (FMR1) gene causing adult-onset ...of fragile X mental re- tardation protein, resulting in fragile X syndrome 5 ...
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Progress toward therapeutic potential for AFQ056 in Fragile X syndrome
... Abstract: Fragile X syndrome (FXS) is the most common form of inherited intellectual dis- ability and the leading single-gene cause of ...the Fragile X mental retardation protein (FMRP), resulting in ...
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Health systems research in fragile and conflict affected states: a qualitative study of associated challenges
... of fragile, conflict- affected, and post-conflict states vary in the literature and among development agencies, broad consensus defines a ‘fragile state’ as one that fails to maintain rule of law or per- ...
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Trinidad and Tobago joint annual report 2007
... 31.12.07 governance economic and institutional reforms Non State Actors NGO Peace and security conflict prevention and fragile states conflict prevention and fragile states European Part[r] ...
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A SURVEY OF DIFFERENT AUTHENTICATION TECHNIQUE FOR WATERMARKING
... a fragile watermark in opposition to robust watermark classically used for copyright protection The basic idea underlying these techniques is to insert a specific watermark (generally independent of the image data ...
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