functional annotation
Computational Techniques for the Functional Annotation of Hypothetical ORFS in Human Chromosome 3
... Among the 23 pairs of chromosomes in the human genome, Chromosome 3 spans almost 200 million base pairs and represents about 6.5 percent of the total DNA in cells. Identifying genes on each chromosome is an active area ...
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The Viral MetaGenome Annotation Pipeline (VMGAP): An automated tool for the functional annotation of viral Metagenomic shotgun sequencing data
... the functional annotation of viral metagenomic sequence ...MetaGenome Annotation Pipeline (VMGAP) pipeline takes advan- tage of a number of specialized databases, such as collections of mobile ...
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Homology modeling and functional annotation of bubaline pregnancy associated glycoprotein 2
... protein annotation resource con- sisting of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length pro- ...for functional annotation of bu ...
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Gene3D: comprehensive structural and functional annotation of genomes
... One of the primary focuses of our research is to extend experimentally derived molecular studies to the vast number of experimentally uncharacterized proteins through bioinformatic methods. One of the most powerful means ...
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Detecting functional rare variants by collapsing and incorporating functional annotation in Genetic Analysis Workshop 17 mini exome data
... the functional annotation information are compared with the list of truly associated SNPs to gen- erate the ROC curves and their AUC scores, which are shown in Figure ...incorporating functional ...
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Heterologous expression of plasmodial proteins for structural studies and functional annotation
... for the development of new drugs. However, it is obvious from the nearly 60% of hypothetical proteins in the para- site genome that have not yet been annotated, that rela- tively little of the biology of the parasite is ...
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Original Article A database and functional annotation of NF-κB target genes
... Abstract: Backgrounds: The previous studies show that the transcription factor NF-κB always be induced by many inducers, and can regulate the expressions of many genes. The aim of the present study is to explore the ...
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Comparison of assembly algorithms for improving rate of metatranscriptomic functional annotation
... vs. 13,706 for the next best-performing algorithm, Metavelvet with k = 27). Of these, only 5,561 contigs were >180 bp in length compared to 3,856 for Metavelvet ( k = 27). Furthermore, Trinity assembled contigs had a ...
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Structural and Functional Annotation of Uncharacterized Protein in Bacillus anthracis A2012
... Several bioinformatics tool for identification of: motif and domain search, transmembrane analysis, membrane protein topology, sequence similarity, protein solubility, [r] ...
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Subtype classification and functional annotation of L1Md retrotransposon promoters
... We developed a computational pipeline which is capable of detecting monomers as the L1Md promoters. Applica- tion of this pipeline in multiple mouse species discovered monomers successfully. Comprehensive comparison of ...
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IN SILICO ANALYSIS AND MOLECULAR DOCKING TO PREDICT THE IMPACT OF GENES ASSOCIATED WITH RHEUMATOID ARTHRITIS
... the functional annotation of a total of 267 genes from GWAS was performed through Gene Ontology (GO) analysis using DAVID which reported 216 genes and 238 GO terms for biological processes ...
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Identification and potential mechanisms of a 4-lncRNA signature that predicts prognosis in patients with laryngeal cancer
... a functional annotation analysis suggested that the mechanisms by which these lncRNAs influence prognosis in laryngeal cancer may involve the extracellular exosome, the Notch signaling pathway, ...
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Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopment
... of functional en- richment using the online Functional Annotation Cluster- ing tool from the Database for Annotation, Visualization, and Integrated Discovery (DAVID, version ...three ...
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Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome
... incorporate functional annotation of regulatory elements to prioritize the dis- ease risk-associated SNPs that are located in non-coding regions of the genome for follow-up studies, (2) various ...
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Supplement
... the functional annotation process using different databases (here KEGG -metabolism- and CARD -antibiotic resistance- ...CARD functional profiles for each ...parameters. Functional profiles can ...
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Pedigree based DNA sequencing pipeline for germline genomes of cancer families
... point of the pipeline is the functional annotation of the po- tential causal variants. As an initial filtering we use here the CADD score, which combines data from different sources. For different regions ...
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GCGene: a gene resource for gastric cancer with literature evidence
... unified functional annotation, we used Entrez gene IDs as the key in all the tables of our GCGene database to cross-link the same genes from different public bioinformatics ...
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A proteomic analysis of acute leukemia cells treated with 9-hydroxyoctadecadienoic acid
... Functional annotation analysis showed that the differential proteins were involved in various biological processes such as mRNA metabolic process, protein binding, DNA replication, respo[r] ...
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Draft genome sequences and description of Lactobacillus rhamnosus strains L31, L34, and L35
... genome annotation pipeline, fol- lowed by a round of manual curation using the JGI GenePRIMP pipeline ...manual functional annotation was performed with the Integrated Microbial Genomes Expert Review ...
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Draft genome sequence of Rubidibacter lacunae strain KORDI 51-2T, a cyanobacterium isolated from seawater of Chuuk lagoon
... and functional annotation of the genome sequence was basically performed within the Integrated Microbial Genomes – Expert Review (IMG-ER) platform ...
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