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Gadolinium-based contrast agents (GBCAs)

Revisiting the risks of MRI with Gadolinium based contrast agents—review of literature and guidelines

Revisiting the risks of MRI with Gadolinium based contrast agents—review of literature and guidelines

... Gadolinium-based contrast agents (GBCA) have been linked to the occurrence of nephrogenic systemic fibrosis (NSF) in renal impaired ...of contrast-enhanced magnetic reso- nance imaging ...

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Eichel, Vanessa
  

(2019):


	In vivo assessment of hair cell toxicity of gadolinium-based contrast agents in Xenopus embryos.


Dissertation, LMU München: Medizinische Fakultät

Eichel, Vanessa (2019): In vivo assessment of hair cell toxicity of gadolinium-based contrast agents in Xenopus embryos. Dissertation, LMU München: Medizinische Fakultät

... using gadolinium-based contrast agents represents an important tool in the diagnosis of the ...The gadolinium-based contrast agents (GBCAs) used in the procedure ...

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Visible T1-hyperintensity of the dentate nucleus after multiple administrations of macrocyclic gadolinium-based contrast agents: yes or no?

Visible T1-hyperintensity of the dentate nucleus after multiple administrations of macrocyclic gadolinium-based contrast agents: yes or no?

... macrocyclic gadolinium-based contrast agents (GBCAs) is currently a source of debate and ...of gadolinium (Gd) from the linear chelating molecule and its subsequent retention in the ...

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Inductively coupled plasma with mass-spectrometry method development and validation for gadolinium in gadolinium-based contrast agents of pharmaceutical formulations

Inductively coupled plasma with mass-spectrometry method development and validation for gadolinium in gadolinium-based contrast agents of pharmaceutical formulations

... chelating gadolinium compounds are far less toxic as they can carry gadolinium through the kidneys and out of body before free ion can be released into ...chelated gadolinium compounds ...

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High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1 Weighted MR Images: Comparison between Gadobutrol and Linear Gadolinium Based Contrast Agents

High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1 Weighted MR Images: Comparison between Gadobutrol and Linear Gadolinium Based Contrast Agents

... linear gadolinium-based contrast agents. Linear gadolinium-based contrast agents included gadoversetamide, gadobenate dimeglumine, and ...

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The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes

The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes

... and contrast-enhanced MRI ...iodinated contrast agent (ICA), probably due to enhanced photoelectric absorp- tion of x-rays by injected iodine atoms ...In contrast, no alterations in DNA double-strand ...

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Diagnostic value of alternative techniques to gadolinium-based contrast agents in MR neuroimaging—a comprehensive overview

Diagnostic value of alternative techniques to gadolinium-based contrast agents in MR neuroimaging—a comprehensive overview

... to contrast-enhanced techniques ...of contrast-enhanced MRI for spe- cific diagnostic questions in ...GBCA contrast enhancement. Briefly, the topic of dynamic contrast-enhanced MRI is ...with ...

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Gadolinium Deposition in Deep Brain Structures: Relationship with Dose and Ionization of Linear Gadolinium Based Contrast Agents

Gadolinium Deposition in Deep Brain Structures: Relationship with Dose and Ionization of Linear Gadolinium Based Contrast Agents

... Our study has several limitations. First, because the number of subjects receiving macrocyclic GBCA was small, this study could not examine the difference between the use of linear and macro- cyclic GBCAs. Second, as ...

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Immediate Adverse Reactions and Anaphylaxis Associated with Gadolinium-based Contrast Agents in a Patient with Meningioma: Case Report and Literature Review

Immediate Adverse Reactions and Anaphylaxis Associated with Gadolinium-based Contrast Agents in a Patient with Meningioma: Case Report and Literature Review

... Allergic-like reactions were classified as mild, moderate, or severe. Mild allergic-like reactions were characterized by one or more of the following: hives, pruritus, localized facial edema, nasal congestion, sneezing, ...

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Retention of Gadolinium Based Contrast Agents in Multiple Sclerosis: Retrospective Analysis of an 18 Year Longitudinal Study

Retention of Gadolinium Based Contrast Agents in Multiple Sclerosis: Retrospective Analysis of an 18 Year Longitudinal Study

... non-gadolinium-based contrast agent– exposed healthy controls by an unpairedt ...of gadolinium- based contrast agent administrations were associated with an increased Signal ...

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Minimizing Risk of Nephrogenic systemic fibrosis in Cardiovascular Magnetic Resonance

Minimizing Risk of Nephrogenic systemic fibrosis in Cardiovascular Magnetic Resonance

... of contrast enhanced imaging techniques allows the assessment of perfusion, tissue viability and detailed angiographic ...use Gadolinium based contrast agents ...these contrast ...

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Native T1 mapping detects the location, extent and patterns of acute myocarditis without the need for gadolinium contrast agents

Native T1 mapping detects the location, extent and patterns of acute myocarditis without the need for gadolinium contrast agents

... low, gadolinium-based contrast agents are associated with the rare but serious compli- cation of nephrogenic systemic fibrosis in patients with significant renal impairment ...

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Gadolinium Based Contrast Agent Accumulation and Toxicity: An Update

Gadolinium Based Contrast Agent Accumulation and Toxicity: An Update

... practice, gadolinium-based contrast agents have been considered safe when used at clinically recommended doses in patients without severe renal ...between gadolinium-based ...

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Gadolinium Contrast Agents for CNS Imaging: Current Concepts and Clinical Evidence

Gadolinium Contrast Agents for CNS Imaging: Current Concepts and Clinical Evidence

... the contrast agent may theoret- ically accumulate faster in the target lesion, enhancing back- ground tissues would also be expected to similarly accumulate that same amount more ...dose, based on the ...

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Magnetic Resonance Imaging of synovitis in knees of patients with osteoarthritis without injected contrast agents using T1 quantification

Magnetic Resonance Imaging of synovitis in knees of patients with osteoarthritis without injected contrast agents using T1 quantification

... intravenous gadolinium based contrast agents an estimated Glomerular Filtration Rate (eGFR) was obtained and for safety reasons [8], ...

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Biocompatible Polyhydroxyethylaspartamide based Micelles with Gadolinium for MRI Contrast Agents

Biocompatible Polyhydroxyethylaspartamide based Micelles with Gadolinium for MRI Contrast Agents

... Several approaches to slow the rotational motion of gadolinium-based contrast agents and thus to improve their relaxation efficiency have been reported in the literature. Macromolecular Gd ...

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Native T1-mapping detects the location, extent and patterns of acute myocarditis without the need for gadolinium contrast agents

Native T1-mapping detects the location, extent and patterns of acute myocarditis without the need for gadolinium contrast agents

... low, gadolinium-based contrast agents are associated with the rare but serious compli- cation of nephrogenic systemic fibrosis in patients with significant renal impairment ...

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An experimental phantom study of the effect of gadolinium-based MR contrast agents on PET attenuation coefficients and PET quantification in PET-MR imaging: application to cardiac studies

An experimental phantom study of the effect of gadolinium-based MR contrast agents on PET attenuation coefficients and PET quantification in PET-MR imaging: application to cardiac studies

... Gadolinium-based contrast agents (GBCA) represent the most common types of magnetic resonance contrast agents, used primarily as a T1 contrast ...chelating agents ...

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Comparison of Two Superparamagnetic Viral Sized Iron Oxide Particles Ferumoxides and Ferumoxtran 10 with a Gadolinium Chelate in Imaging Intracranial Tumors

Comparison of Two Superparamagnetic Viral Sized Iron Oxide Particles Ferumoxides and Ferumoxtran 10 with a Gadolinium Chelate in Imaging Intracranial Tumors

... different contrast agents other than gadolinium-based contrast ...low-molecular-weight gadolinium, it does not nec- essarily mean that it is leaky enough to allow larger sized ...

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Functional Brain Imaging Using a Long Intravenous Half Life Gadolinium Based Contrast Agent

Functional Brain Imaging Using a Long Intravenous Half Life Gadolinium Based Contrast Agent

... The activation volume was significantly larger for the BOLD fMRI measurements in our preparation by using our predetermined Z thresholds. However, making this compari- son is problematic because the Z threshold for both ...

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