Gap Junctions
Gap junctions in Malpighian tubules of Aedes aegypti
... of gap junctions in Malpighian tubules of insects that may underlie the nearly perfect electrical coupling of membrane voltages and their ...through gap junctions may reflect geometric and/or ...
14
Gap Junctions and NCA Cation Channels Are Critical for Developmentally Timed Sleep and Arousal in Caenorhabditis elegans
... that gap junctions function downstream of other proteins known to regulate ...elegans gap junctions function downstream of the cGMP-dependent protein kinase EGL-4 in sleep, suggest- ing a ...
13
Gap junctions in the adult and developing cerebral cortex of the rat: Regional differences in their distribution and cellular localization of connexins
... micrographs, gap junctions are defined as heptalaminar structures between intimately apposed plasma membranes separated by a gap of 2-3 ...preparations, gap junction plaques appear as ...
289
Left right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions
... Fig. 6. A model for LR asymmetry in conjoined twins. (A) The two organizers are posi- tioned in a single blastoderm. The left and right sides of each twin are indicated. Note that the left side of the primary twin is ...
12
Downregulation of Gap Junctions in Astrocytes by Monoclonal Antibodies against the Second Extracellular Loop of Connexin-43
... The flow cytometry analysis in the control experiment series (without addition of antibodies) allowed distinguishing several subpopulations of fluorescent cells. Initially labeled cells were identified as Calcein ...
10
Upregulation of Connexins 30 and 32 Gap Junctions in Rat Hippocampus at Transcription Level by Chronic Central Injection of Lipopolysaccharide
... diseases. Gap junctions are specialized cell-cell contacts between eukaryotic cells, composed of aggregates of transmembrane ...(Cx). Gap junctions directly connect the cytoplasm of adjacent ...
6
NO, via its target Cx37, modulates calcium signal propagation selectively at myoendothelial gap junctions
... myoendothelial gap junction ...homotypic gap junctions at myoendothelial contacts as found for example in isolated thoracodorsal arteries [41] may even lead to NO induced improvement of GJC, since ...
14
Calcium-mediated transductive systems and functionally active gap junctions in astrocyte-like GL15 cells
... In mammalian astrocytes, extracellular physiological ag- onists are able to increase the concentration of intracel- lular Ca 2+ ([Ca 2+ ] i ) via voltage-dependent channels or controlled release from internal stores (via ...
15
Sex differences in endothelial function in porcine coronary arteries: a role for H2O2and gap junctions?
... barium-sensitive inwardly rectifying potassium channels and the ouabain-sensitive Na + /K + ATPase pump respectively (Edwards et al., 1998; 2010). Gap junctions are formed from two docking hemichannels with ...
16
Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions
... of gap junction communications between the two cell ...of gap junctions by carbenoxolone blocks the transfer of the anti-tumor miR-145-5p from HMEC to U87, and the transfer of the pro- invasive ...
10
The Distribution and Functional Properties of PMLD-Linked CX47 Mutations on CX47/CX47 Homotypic and CX47/CX43 Heterotypic Gap Junctions
... Gap junctions (GJ) are ubiquitous clusters of intercellular channels formed between neighbouring ...Each gap junction channel is formed by two end-to- end docked hemichannels, also known as ...
86
Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight junction structure
... adherens junctions, tight junctions (TJs), and gap junctions ...adherens junctions, organized in a similar manner to TJs with transmembrane cadherins and adapter proteins, are affected ...
15
Khandoga, Natascha (2007): Einfluss von oxLDL auf die Apoptoseinduktion und Zellkopplung über Gap Junctions. Dissertation, LMU München: Medizinische Fakultät
... anderes experimentelles Setup gewählt, in dem Connexin-exprimierende Zellen daran gehindert wurden, Zellkontakte miteinander zu bilden. Dieser Versuchaufbau sollte es ermöglichen, den Effekt der Connexine von dem der ...
133
Granulosa cells regulate intracellular pH of the murine growing oocyte via gap junctions: development of independent homeostasis during oocyte growth
... via gap junctions. However, whether such gap junctional proton permeability holds physiological relevance was ...that gap junction-mediated pH cooperativity allows the granulosa cells to ...
9
Facilitation of Hippocampal Kindling and Exacerbation of Kindled Seizures by Intra-CA1 Injection of Quinine: A Possible Role of Cx36 Gap Junctions
... For years, chemical synaptic transmission has been considered as the main mechanism involved in aberrant neuronal synchrony in seizures. Later, the role of gap junctions (GJs) was elucidated [2,3] . Every ...
7
Pintsch, Monika (2015): Cx37 abhängige Calciumsignalausbreitung durch myoendotheliale Gap Junctions. Dissertation, LMU München: Medizinische Fakultät
... über Gap Junction-Kanäle erfolgen, die als interzelluläre Verbindungen den Austausch von elektrischen und chemischen Signalstoffen zwischen benachbarten Zellen ...von Gap Junction-Kanälen reguliert ...die ...
84
Role of the gap junctions in the contractile response to agonists in pulmonary artery from two rat models of pulmonary hypertension
... [3]. Gap junctions allow cell-to-cell coupling in between vascular cells of the same type, namely endothelial or smooth muscle cells but they are also present in between endothelial and smooth muscle cells ...
13
The assembly of developing motor neurons depends on an interplay between spontaneous activity, type II cadherins and gap junctions
... We hypothesised that SA might collaborate with cadherins to regulate nucleogenesis, with an adjunct role played by gap junctions (Fig. 1A). Whereas spontaneous electrical activity is known to regulate the ...
7
Gap junctions, dendrites and resonances : a recipe for tuning network dynamics
... as gap junctions, are known to be impor- tant in mediating various brain rhythms in both normal [6, 7] and pathological [8–10] ...Each gap junction contains numerous connexon hemi-channels, which ...
28
Differential regulation of gap junctions by proinflammatory mediators in vitro
... the gap junctions established in a single cell to communi- cate with different cell populations possess different physical and/or regulatory properties, dictated primarily by their con- nexin ...
6