Gene and transcript
Differential analysis of gene regulation at transcript resolution with RNA-seq
... at gene- and transcript-level resolution simultaneously, and therefore do not realize the full potential of the assay to capture transcriptome ...each transcript across ...accurate ...
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Functional divergence and convergence between the transcript network and gene network in lung adenocarcinoma
... between transcript isoforms, transcript-based and gene-based networks (designated as “TN” and “GN”, respectively) are expected to differ considerably from each other in function, regulation, and ...
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Development and exploitation of GeneFriends: An online database for gene and transcript co-expression analysis
... RNA-seq-based gene and transcript co-expression database A human RNA-seq-based gene and transcript co- expression database In the previous chapter, we have established a web interface and ...
233
Triple-layer dissection of the lung adenocarcinoma transcriptome – regulation at the gene, transcript, and exon levels
... single- transcript genes, for which gene- and transcript-level regulations were virtually ...of transcript-/exon-specific regulatory events could be found in lung adenocarcinoma ...
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Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences
... even gene-level DTE results may suffer from lack of ...the gene or dif- ferential relative usage of its transcripts, or a combination of the two ( Figure 2B ...the transcript level are still often ...
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Gene-level differential analysis at transcript-level resolution
... a gene per condition can mask dynamic effects among its multiple constituent transcripts (Figure ...to gene abundance. In “domination” (Figure 2b), an abundant transcript that is not changing can ...
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Gene level differential analysis at transcript level resolution
... 88% of reads were retained after applying this filter. The remaining TCCs were used to perform differential ex- pression with sleuth [9] and DESeq2 [18] by using TCCs in lieu of transcript/gene counts. In ...
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An antisense transcript in the human cytomegalovirus UL87 gene region
... nucleotides transcript having an antisense orientation to the UL87 gene was found in a late HCMV cDNA ...antisense transcript was confirmed by Rapid amplification of cDNA ends (RACE) and Northern ...
9
A Brassica exon array for whole transcript gene expression profiling
... per gene and retain certain advantages over direct ...142,997 gene models identified. The assembled gene models were then used to establish a comprehensive public WT exon array for transcriptomics ...
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Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript
... O R I G I N A L I N V E S T I G A T I O N Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript Z. Kote-Jarai • A. Amin Al Olama • D. Leongamornlert • M. Tymrakiewicz ...
8
Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences
... average transcript length across samples when performing DGE, either in the definition of the count matrix (scaledTPM) or by defining offsets, led to consider- ably improved false discovery rate (FDR) control ...
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Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats
... In the present study, our aim was to investigate whether cardiac gene expression is influenced by metabolic syn- drome. Here we show several characteristics of metabolic syndrome in 25 weeks old male ZDF rats ...
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Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene Promotes Neuronal Survival
... 0.7-kb transcript that is contained entirely within the region deleted was recently reported ...this transcript is unclear since it was found in only two of four laboratory strains examined and was not ...
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Expression of the Pseudorabies Virus Latency-Associated Transcript Gene during Productive Infection of Cultured Cells
... The effect of the DNA synthesis inhibitor, araC, on the transcription of the 2.0-kb RNA also was examined in both PrV-infected MDBK and N1E cells. In this case, total RNA from araC-treated, virus-infected cells was ...
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Analysis of differences in gene expression and the genetic regulation of transcript accumulation in maize inbred and hybrid lines
... differential transcript accumulation potentially influences protein accumulation differences in inbreds and their ...compared transcript accumulation differences in B73 and Mo17 with only one of the ...
108
Identification of the Pseudorabies Virus Promoter Required for Latency-Associated Transcript Gene Expression in the Natural Host
... latency-associated transcript (LAT) gene is a hallmark of alphaherpesvirus latency, and yet its control and function remain an ...LAT gene transcription so that the influence of the resultant RNA can ...
6
The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency.
... latency-associated transcript (LAT), is abundantly ...LAT gene was deleted established latency in only 10% of trigeminal neurons (P < ...LAT gene serves to increase the number of neurons in which ...
9
Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript
... factor gene ZNF257, causing a significant reduction in the total expression level of this gene in lymphoblastoid cell ...fusion transcript that is generated exclu- sively from inverted chromosomes ...
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The Latency-Associated Transcript Gene Enhances Establishment of Herpes Simplex Virus Type 1 Latency in Rabbits
... latency-associated transcript (LAT) gene the only herpes simplex virus type 1 (HSV-1) gene abundantly transcribed during neuronal latency, is essential for efficient in vivo ...
7
Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lyticgene promoters in latent infection
... ICP4 gene transcripts, and 10-fold lower levels of TK gene transcripts at 30 dpi ...a gene product from this region plays an active role in this ...the gene-specific silencing mechanisms that ...
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