Gene-by-Environment Interaction (GxE)
Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics approach
... of gene-by-environment interaction that shows evidence of influencing the comor- bidity and is consistent with established knowledge about AUD and depression ...Entrez Gene and PubMed, ...
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Developing a synthetic psychosocial stress measure and harmonizing CVD risk data: a way forward to GxE meta and mega analyses
... GxE: gene-by-environment interaction; SNP: sin- gle nucleotide polymorphism; EBF1: early B-cell factor 1; BDNF: brain-derived neurotrophic factor; 5HTR2C: 5-hydroxytryptamine receptor 2C; dbGaP: ...
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Selection of genes for gene-environment interaction studies: a candidate pathway-based strategy using asthma as an example
... the Gene Ontology (GO) database (Gene Ontology Consortium [13,14]), as described in the online tutorial [see Additional file ...and gene product attributes across species and ...describing ...
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Genotype x environment interaction on experimental hybrids of chili pepper.
... x environment interaction (GxE) (Cruz et ...this interaction occurs when genes controlling certain trait or the level of gene expression thereof differ among diverse ...Such interaction ...
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Operating Characteristics of Statistical Methods for Detecting Gene-by-Measured Environment Interaction in the Presence of Gene-Environment Correlation under Violations of Distributional Assumptions
... In the past few decades, it has become increasingly clear that any inquiry into the roots of psychopathology such as anx- iety or depression, as well as other complex behaviors, re- quires accounting for possible ...
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Early predictors of behavioural problems in pre-schoolers – a longitudinal study of constitutional and environmental main and interaction effects
... early environment and constitutional factors for child behaviour at preschool ...the gene-by-environment interaction of 5-HTTLPR, BDNF Val66Met and experience of multiple life events on ...
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Gene environment interaction impacts on heart development and embryo survival
... a gene-environment interaction (GxE) between genetic predisposition to vertebral segmentation defects and short- term gestational hypoxia (Sparrow et ...
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Gene environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis
... and result in exaggerated risks. Nevertheless, this was unlikely to have affected our findings since the TGF b 1 polymorphisms we examined did not deviate from Hardy- Weinberg Equilibrium (HWE) in the control population. ...
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Interaction between ELMO1 gene polymorphisms and environment factors on susceptibility to diabetic nephropathy in Chinese Han population
... ELMO1 gene fam- ily; secondly, we selected the SNPs within ELMO1 gene, which have been reported in previous studies, but no consistent results were obtained on the relation between SNPs and DN ...
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Gene environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis
... examine interaction, between gene polymorphisms and BMI, multiplicative and additive models of interac- tion were ...an interaction term (genotype*BMI) was included in a logistic regression ...
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Religious Attendance Moderates the Environmental Effect on Prosocial Behavior in Nigerian Adolescents
... the gene–environment (G × E) interaction model- fi tting approach (Purcell, 2002), Button et ...E interaction effects to influence ...E interaction in the relationship between ...
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PubMedCentral-PMC5739051.pdf
... assessing gene- environment interaction using NBDPS data include relatively small numbers of infants with each birth defect, suboptimal sample collection rates, and self-reported exposure data ...
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Maternal iron metabolism gene variants modify umbilical cord blood lead levels by gene-environment interaction: a birth cohort study
... a gene-environment interaction between iron metabolism genotype and MBL by regressing log-transformed values of UCBL on similarly- transformed values of ...respective interaction with MBL, ...
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Pattern based mining strategy to detect multi locus association and gene × environment interaction
... As genome-wide association studies grow in popularity for the identification of genetic factors for common and rare diseases, analytical methods to comb through large numbers of genetic variants efficiently to identify ...
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A powerful statistical method identifies novel loci associated with diastolic blood pressure triggered by nonlinear gene environment interaction
... of gene-environment (G × E) interactions in determining the risk of a variety of diseases such as respiratory diseases [1], obesity [2], and psychiatric disor- ders ...E interaction, see the work of ...
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Gene-environment interaction tests for family studies with quantitative phenotypes: A review and extension to longitudinal measures
... Through this model, the main genetic and environmental effects and gene – environment inter- actions can be assessed using standard statistical soft- ware. Additional advantages of this model are that ...
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Interaction between stress and the BDNFVal66Met polymorphism in depression: a systematic review and meta-analysis
... Variety of data were extracted from included studies in accordance with other gene-environment interaction re- views [37,62] (see Table 2). When publications reported results for both childhood ...
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Genetic association analysis of coronary heart disease by profiling gene environment interaction based on latent components in longitudinal endophenotypes
... to environment exposures, and as such, are likely to contain hidden information of gene-environment (G × E) ...kinase gene (TNNI3K), with potential G × E interactions independent of time and ...
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A Newly Identified Susceptibility Locus near FOXP1 Modifies the Association of Gastroesophageal Reflux with Barrett's Esophagus
... potential interaction with the SNPs: cigarette-smoking, BMI (weight (kg)/ height 2 (m 2 )), and gastroesophageal reflux ...the environment exposure and genotype ...the interaction was assessed by a 1 ...
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Gene-Environment Interaction in Chronic Disease
... The identification of genetic or epigenetic asso- ciations with disease phenotypes facilitates risk stratification and can therefore help to guide mon- itoring and prevention. In order to convert these observations into ...
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