genetic analysis
Genetic analysis of subsequent second primary malignant neoplasms in long-term pancreatic cancer survivors suggests new potential hereditary genetic alterations
... lymphatic, vascular, and perineural invasion, the therapy administered and follow-up, were obtained from medical records. The main clinical characteristics of the whole group are summarized in Table 1. The retrospective ...
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Penalized regression based multimarker genotype analysis of Genetic Analysis Workshop 17 data
... minimized with a cyclic coordinate descent algorithm, allowing quick coefficient estimation for a large number of markers. We compare our method to single-marker analysis and a gene-based sparse group LASSO on the ...
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Application of collapsing methods for continuous traits to the Genetic Analysis Workshop 17 exome sequence data
... Genetic Analysis Workshop 17 used real sequence data from the 1000 Genomes Project and simulated phenotypes influenced by a large number of rare ...for analysis of multiple rare ...single-marker ...
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Genetic association analysis using weighted false discovery rate approach on Genetic Analysis Workshop 18 data
... of genetic markers are ...For Genetic Analysis Workshop 18, we applied the method of false discovery rate control with p value weighting on family-based association tests on quantitative trait to ...
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Case control association testing by graphical modeling for the Genetic Analysis Workshop 17 mini exome sequence data
... We generalize recent work on graphical models for linkage disequilibrium to estimate the conditional independence structure between all variables for individuals in the Genetic Analysis Workshop 17 ...
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Propensity score analysis in the Genetic Analysis Workshop 17 simulated data set on independent individuals
... Genetic Analysis Workshop 17 provided simulated phenotypes and exome sequence data for 697 independent individuals (209 case subjects and 488 control ...with genetic risk factors into a single risk ...
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Evaluation of a LASSO regression approach on the unrelated samples of Genetic Analysis Workshop 17
... In the Genetic Analysis Workshop 17 (GAW17) simu- lated data set, there are no missing genotype data. Among all the 24,487 SNPs, 91% have a MAF less than 0.1, 87% have a MAF less than 0.05, and 75% have a ...
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Genetic association analysis for common variants in the Genetic Analysis Workshop 18 data: a Dirichlet regression approach
... other genetic and phenotypic data for GAW18 were provided by the San Antonio Family Heart Study and San Antonio Family Diabetes/Gallbladder Study, which are supported by NIH grants P01 HL045222, R01 DK047482, and ...
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Gaussian graphical models for phenotypes using pedigree data and exploratory analysis using networks with genetic and nongenetic factors based on Genetic Analysis Workshop 18 data
... analyzed Genetic Analysis Workshop 18 (GAW18) data, which includes genome-wide association data for 400,000 SNPs, along with simulated and real phenotypic information SBP, DBP, hypertension, blood pressure ...
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Population genetic analysis and conservation strategies for redtail shrimp Fenneropenaeus penicillatus using ten microsatellite markers.
... The F ST value in our study, mostly because of the high F ST between the HN population and other 11 populations, was much higher than that of F. chinensis (0.01045-0.03569, Meng et al., 2009), but lower than that of ...
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Identification and genetic analysis of Kadipiro virus isolated in Shandong province, China
... BAV is the prototype species of the genus Seadorna- virus and was first isolated in 1987 from patients with encephalitis in Xishuangbanna prefecture, Yunnan prov- ince, China [5]. To date, BAV has been isolated from ...
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Genetic analysis of porcine circovirus type 2 from pigs affected with PMWS in Chile reveals intergenotypic recombination
... cluster contained viruses from 6 different pig farms with nu- cleotide identity of 99.5%. These sequences were detected as recombinants using RDP3 software and the recombination events were statistically supported by ...
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Genetic epidemiology: Approaches to the genetic analysis of rheumatoid arthritis
... linkage analysis will be greatly ...a genetic relative risk of 2 (for the heterozygote) for a disease allele of 20% fre- quency with a significance level of P = 5 × 10 –8 ...
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Analysis of Genetic Analysis Workshop 18 data with gene based penalized regression
... the analysis of RVs that group or collapse variants within a region, gene, or gene ...for analysis, and require the use of a minor allele frequency (MAF) threshold to define a ...
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A GENETIC ANALYSIS OF VARIEGATION
... up of con- trasting gene elements, interchange parts between mitoses any accumula- tion of one kind of gene element in one of the genes might be negatived by an accumulatio[r] ...
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Genetic analysis and identification of SSR markers associated with rice blast disease in a BCF backcross population.
... the genetic plasticity of the pathogen ...on genetic resistance and virulence stability are vital to increase our understanding of the molecular basis of blast disease ...
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Comparative genetic analysis and pathological characteristics of goose parvovirus isolated in Heilongjiang, China
... phylogenetic analysis of the H strain VP and NS genes showed that the H strain was closely related to Chinese mainland strains that were isolated over the past 20 ...GPV genetic groups circulating in ...
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Enrichment analysis of genetic association in genes and pathways by aggregating signals from both rare and common variants
... the Genetic Analysis Workshop 17 simulated data, we test a two-step strategy that first applies a collapsing method in a gene-level analysis and then aggregates the gene-level test results by ...
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THE SEARCH FOR MATING-TYPE-LIMITED GENES IN THE HOMOTHALLIC ALGA CHLAMYDOMONAS MONOICA
... Genetic analysis o f the mtl-2 mutation: Preliminary genetic analysis of clone Fdl9-42 was designed to separate the FdURD-induced mutation (mtl-2) from the originally assoc[r] ...
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INDUCTION AND ANALYSIS OF GENE MUTATIONS IN CULTURED MAMMALIAN SOMATIC CELLS
... The ability to induce mutations in mammalian cells in culture not only increases the genetic variability that is prerequisite for genetic analysis but also permits studies in the[r] ...
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