genetic background
Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice
... Ultrasonic vocalizations on postnatal day 7 also showed a significant difference between genotypes on the B6 back- ground, but this difference was in the opposite direction of that observed on the 129 background. ...
11
Causes and Consequences of Genetic Background Effects Illuminated by Integrative Genomic Analysis
... the background dependence of numerous conditionally lethal gene deletions (Dowell et ...These background polymor- phisms may also have multifactorial consequences, such as pleiotropic effects on other ...
39
Multiple Effects of Genetic Background on Variegated Transgene Expression in Mice
... 29% in the C57BL/6 population and 47% in the CBA Modifiers of variegation: The BLG/7 locus displays population). Thus, factors contributing to inbreeding variable expression in both 13th generation CBA and depression may ...
6
Interstitial lung disease in children – genetic background and associated phenotypes
... a genetic risk for interstitial lung disease, which becomes apparent in dependence of the genetic background, ...as genetic diagnoses can be made and underlying etiologies of famil- iar cases ...
16
Genetic Background Influences Brassinosteroid Related Mutant Phenotypes in Rice
... The phenotype of Taichung 65-derived null allele d2-1 was semi-dwarf: plants reached ~55% (about 60 cm) of the total culm length of wild-type Taichung 65 (about 110 cm; Figures 5(a), (b) and (e)). Interestingly, the ...
10
Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background
... A genetic mapping study in a back- cross of (C57BL/6 ⫻ SPRET/Ei)F1 ⫻ C57BL/6 mice identified Mx1 as the major resistance locus ...whether genetic background or the specific Mx1 allele in CAST/EiJ ...
12
Genetic background affects induced pluripotent stem cell generation
... if genetic background affects the efficiency of generating iPSCs dur- ing early reprograming as well as the pluripotent stability of the iPSCs during later stages of ...their genetic diversity ...
9
The Influence of Genetic Background on Stem Cell Derivation and Variability.
... WSB background and acquired two chromosomally normal XY males, two chromosomally normal XX females, and one autosomal abnormal female within testing only five iPSC ...that genetic background ...
300
Zinc, oxidative stress, genetic background and immunosenescence: implications for healthy ageing
... the genetic background has been acquired or is emerging, based on innovative methods and technologies for the assay of zinc ion availability and the related activity of zinc-dependent ...
8
Genetic background determines response to hemostasis and thrombosis
... of genetic muta- tions have been identified, these account for only a small percentage of the CVD in human ...multiple genetic and environmental factors ...as genetic determinants of susceptibility ...
12
Effects of Genetic Background on Response to Selection in Experimental Populations of Arabidopsis thaliana
... Selection coefficients also can be estimated for differ- ent genomic regions by determining the magnitude of selection coefficient required to produce the observed allele frequency changes. Estimated selection coeffi- ...
10
Heritability in genetic heart disease: the role of genetic background
... of genetic background on the clinical expression of mutations that cause LQTS, but did not find such effects for mutations that cause DCM and ...more genetic modifiers that underlie incomplete ...
7
SELECTIVE NEUTRALITY OF 6PGD ALLOZYMES IN E. COLI AND THE EFFECTS OF GENETIC BACKGROUND
... H E R E we present evidence that, in a normal genetic background, at least four naturally occurring alleles for allozymes of 6-phosphogluconate dehydro- genase in Escherichi[r] ...
17
Concurrent Massive Pulmonary Embolism and Brachial Artery Embolism in a Genetic Background
... some genetic factors defin- itively increase the risk for arterial or venous throm- bosis, it is still controversial whether or not that risk is augmented by plasminogen activator inhibitor 1 (PAI- 1) and ...
5
The role of genetic background and hypoxia in the chemotherapeutic efficiency in paediatric brain tumours
... Besides the upregulation of drug resistance genes, the strong involvement of hypoxia in cellular energetic, cellular response, tissues invasion and metastasis can all potentially play co[r] ...
258
Mitochondrial genetic background in Ghanaian patients with primary open-angle glaucoma
... Primary open-angle Glaucoma (POAG) is the main cause of irreversible blindness worldwide [1]. Heritability estimates evidenced that POAG has a strong genetic component [2]. In fact, linkage analysis, case-control ...
5
Identification and Characterization of Novel Maize Mirnas Involved in Different Genetic Background
... Differentially expressed miRNAs were detected in the leaves of two maize inbred lines, and 124 known and 68 novel miRNAs were identified using a high-throughput sequencing approach.. [r] ...
13
Large Bowel Genetic Background and Inflammatory Processes in Carcinogenesis – Systematic Review
... Studies of CRC have been focused on sporad- ic and familial cases. Hereditary colon cancer pre- disposition is confirmed in less than 5% of all CRC patients. Detailed information in such cases pro- vides the opportunity ...
9
GENETIC BACKGROUND AND THE FITNESS OF ALLOZYMES
... YAMAZAKI (1971) , using a technique designed to avoid the problems of linkage disequilibrium by utilizing a large number of independent homozygous lines as founders of his exper[r] ...
5
Developmenrt of EST SSR and genomic SSR markers to assess genetic diversity in Jatropha Curcas L
... low genetic variabil- ity found among accessions of ...of genetic variation in ...of genetic var- iation have been identified in Latin America, especially in Guatemala ...of genetic diversity ...
8