Haplotype Analysis
Preimplantation genetic testing for a family with usher syndrome through targeted sequencing and haplotype analysis
... identified for each haplotype on average. The estimated ADO rate of each embryo was ranged from 0 to 31.7%. However enough SNPs remained for haplotype analysis of the embryos. Informative SNPs were ...
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Fine Mapping of HWC2, a Complementary Hybrid Weakness Gene, and Haplotype Analysis Around the Locus in Rice
... of haplotype 3, to Hwc2-1 ...larger haplotype analysis around ...sequence analysis of HWC2 to clarify the relation between the haplotypes and HWC2 alleles or sequence ...
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Linkage, association, and haplotype analysis : A spectrum of approaches to elucidate the genetic influences of complex human traits
... association analysis only has power to detect common causal variants that are in linkage disequilibrium with genotyped ...linkage analysis has greater power to detect rare variants with large effects for ...
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Haplotype analysis of the 5,10 methylenetetrahydrofolate reductase (MTHFR) c 1298A>C (E429A) polymorphism
... Besides historical genetic aspects, the haplotypes pre- sented in this study might be helpful for perinatal diag- nosis of MTHFR deficiency based on haplotype analysis in the case of an unknown MTHFR ...
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Mitochondrial Haplotype Analysis of Pomoxis nigromaculatus Inhabiting Three Georgian Lakes
... moderate haplotype diversity and low nucleotide diversity, which may affect their ability to respond to a rapidly changing environment, especially when coupled with increased fishing ...mtDNA haplotype ...
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Haplotype analysis of leptin gene polymorphisms in obesity among Malays in Terengganu, Malaysia population
... The single association data as presented in Table 1 was found not significantly correlated between G2548A, H1328080, A19G polymorphisms and obesity with the P-value of 0.74, 0.56 and 0.38 respectively. For G2548A ...
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Haplotype analysis within quantitative trait locus affecting intramuscular fat content on porcine chromosome
... ABSTRACT: Previous results of fine mapping for quantitative trait loci affecting intramuscular fat content identified a 3.0-Mb chromosome interval on porcine chromosome 7, which contains at least 9 genes, based on the ...
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Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic breast cancer
... risk haplotype is a subset of the wild-type haplotype, and no coding or potential splice-site SNPs in the NIEHS Environmental Genome Project database are in LD with the SNP defining this ...
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Haplotype Analysis of Peroxisome Proliferator-activated Recep-tor γ Gene Polymorphisms and the Lipoprotein (a) Level
... type analysis is generally used to explore the as- sociation between the diseases and multiple genes by testing some tag SNPs so as to reduce the workload of researches and provide more power- ful and accurate ...
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Haplotype Analysis of the β2 Adrenergic Receptor Gene and Risk of Myocardial Infarction in Humans
... Q27 haplotype and the T164 allele. Thus, the haplotype T164, as compared to the reference haplotype G16-Q27- patterns were further collapsed and stratified using T164 T164, were significantly ...
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Haplotype analysis of the PPAR gamma Pro12Ala and C1431T variants reveals opposing associations with body weight
... PPARG haplotype in the BMI of lean individuals from any of our study groups; however, we consistently see the opposing effects of the polymorphisms in heavier ...
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Haplotype Analysis of β-Thalassaemia Major and Carriers with Filipino β-Deletion in Sabah, Malaysia
... The Filipino β°-deletion is an extensive deletion. Haplotyping can only be conducted at the 5’β-globin gene cluster, the region not affected by the deletion. Thus, the association between haplotype patterns at the ...
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Stepwise haplotype analysis: Are LD patterns repeatable?
... however, relationships among SNPs 3–5 were captured in three different ways. The variability of these 12 simple graphs and of the models they denote is interesting, given the apparently uniform ‘block’ of LD seen in ...
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Density based clustering in haplotype analysis for association mapping
... As a preliminary step toward haplotype association analy- sis, we performed exploratory single-marker scans on case-control samples and trios. An initial scan with ASSOC on case-control samples gave evidence of an ...
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Haplotype analysis of ApoAI gene and sepsis-associated acute lung injury
... The SPSS 17.0 for windows was used for the statistical analysis. For each polymorphism, Hardy-Weinberg equi- librium was assessed using the standard χ 2 test or Fisher’s exact test. Genotype frequencies in cases ...
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Haplotype analysis of case-control data
... fits haplotype-based logistic regression to case-control data and estimates the effects of haplotypes of interest on the disease and, optionally, their interactions with environmental factors using efficient ...
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Detecting Local Haplotype Sharing and Haplotype Association
... our haplotype analysis, GRIK4 was associated with both CAD and RA, both of which are common chronic in- flammatory diseases, and RA patients have an increased prevalence of CAD (Seferovic et ...
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A retrospective method for inference on haplotype main effects and haplotype-environment interactions using clustered haplotypes.
... that haplotype analysis can be more powerful than single SNP analysis, especially when there are multiple disease causing variants (Morris and Kaplan ...of haplotype analysis in ...
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Regression-based multi-marker analysis for genome-wide association studies using haplotype similarity
... complicate haplotype analyses under a GWA ...regular haplotype analysis consumes more degrees of freedom per test than a single-SNP ...a haplotype association test, and the overall performance ...
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Association testing by haplotype sharing methods applicable to whole genome analysis
... these haplotype-sharing methods were as expected and no significant associations in other regions were ...five-SNP haplotype association analysis, but the CROSS test showed more power in each ...
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