Histones and chromatin
Sth1p, a Saccharomyces cerevisiae Snf2p/Swi2p Homolog, Is an Essential ATPase in RSC and Differs From Snf/Swi in Its Interactions With Histones and Chromatin-Associated Proteins
... of chromatin (RSC) in vitro, suggests that it provides RSC with ATP hydrolysis ...in histones and chromatin assembly genes that suppress snf/swi, suggesting that RSC interacts differently with ...
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Interaction of SET domains with histones and nucleic acid structures in active chromatin
... bind histones with di- and trimethylated sub- strate lysine through their histone-recognition ...their chromatin loci per se or for the basic monomethylation of ...recognize histones through their ...
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Linker histones are fine scale chromatin architects modulating developmental decisions in Arabidopsis
... scale chromatin analyses combined with transcriptome and nucleosome profiling reveal distinct roles of H1 on hetero- and euchromatin: H1 is necessary to form heterochromatic domains yet dispensable for silencing ...
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ASF1 is required to load histones on the HIRA complex in preparation of paternal chromatin assembly at fertilization
... paternal chromatin provides yet another dramatic illustration of the different proper- ties of ASF1 and HIRA complex proteins with respect to histone deposition on ...with histones, the HIRA complex must ...
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Human linker histones: interplay between phosphorylation and O-β-GlcNAc to mediate chromatin structural modifications
... Eukaryotic chromatin is a combination of DNA and histone ...and histones. Initial studies emphasize on core histones association with DNA, however later studies prove the importance of linker histone ...
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Differential Hyperacetylation of Histones H3 and H4 upon Promoter-Specific Recruitment of EBNA2 in Epstein-Barr Virus Chromatin
... the chromatin can be determined to within a few 100 ...H4 histones, we can conclude that the re- cruitment of EBNA2 to its target promoters correlates with an increase in the level of histone H3 or H4 ...
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VP16-Dependent Association of Chromatin-Modifying Coactivators and Underrepresentation of Histones at Immediate-Early Gene Promoters during Herpes Simplex Virus Infection
... with chromatin-modifying coactivator proteins of several ...and chromatin-modifying coactivators at IE gene promoters during infection of HeLa cells by wild-type HSV-1 and by RP5, a viral strain lacking the ...
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Studies on the role of histones in the structure and function of chromatin
... In the preparation of chromatin samples for template activity studies we have, therefore, routinely extracted the original purified sheared chromatin three times with 0.15 M NaC1 - 0.[r] ...
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The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus
... of chromatin, and DNA. Whole chromatin was the most reactive substrate, with 88% of the patients ...with chromatin and the (H2A-H2B)-DNA subnucleosome complex but displayed very low or no reactivity ...
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>VOLUME FIVE HUNDRED AND THIRTEEN ENZYMOLOGY. Nucleosomes, Histones & Chromatin Part B
... Genome-Wide Mapping of Nucleosome Occupancy, Histone Modifications, and Gene Expression Using Next-Generation. Sequencing Technology 297 Gang Wei, Gangqing Hu, Kairong Cui, and Keji Zhao[r] ...
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Epigenetic modifications of histones in cancer
... of chromatin-related proteins lack druggable ...grade chromatin-related proteins will significantly advance our understanding of the roles of histone modifications and chromatin in normal biological ...
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Posttranslational Modifications Occur In Histones
... Post-translational modifications PTMs of histones play an important role. Methylation can still developmentally arrest signal, in posttranslational modifications on protein. For instance, a hypermethylated ...
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The effect of linker histones on force-induced nucleosome unstacking
... 2.2 Nucleosome dynamics 11 2.2.3 Single molecule force spectroscopy Magnetic Tweezers is a technique to manipulate single molecules by using single molecule force spectroscopy. The paramagnetic beads are subjected to an ...
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Novel chemokine-like activities of histones in tumor metastasis
... ABSTRACT Histones are intracellular nucleosomal components and extracellular damage-associated molecular pattern molecules that modulate chromatin remodeling, as well as the immune ...that histones ...
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Changes in epigenetic marks on histones along melanoma genesis
... ABSTRACT Among the major disorders in the world, cancer remains the second disease responsible for more deaths in the world and melanoma is one of the most aggressive types of tumor. The tumors, as widely studied, are ...
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Epigenetic marking of sperm by post-translational modification of histones and protamines
... of chromatin PTMs in adult mouse ...sperm chromatin, These results suggest the ex- istence of a ‘protamine code’ in addition to the ‘histone code’ in sperm, the role of which in transgenerational epigenetic ...
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The role of extracellular histones in critical illness and their application in acute pancreatitis
... nuclear chromatin is cleaved into nucleosomes, which are released extracellularly 232 and further degraded into individual ...circulating histones is observed in inflammatory diseases such as sepsis 213 , ...
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Epigenetic marking of sperm by post-translational modification of histones and protamines
... identify chromatin PTMs in mouse sperm, we used a peptide-based bottom-up MS/MS ...these histones, including 40 to 45 peptides from H2A, H2B and H4, 33 from H3 and 14 from H1, with a false discovery rate ...
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On the electrostatics of DNA in chromatin
... possess chromatin, which is mostly composed of complexes of nuclei acids with ...within chromatin is present in the form of protein- DNA complexes called ...
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Chromatin and Transcription in Yeast
... that chromatin structure plays widespread, dynamic, and essential roles in the control of ...of chromatin structure in transcriptional control in vivo and showing that histones play a role in ...
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