Human bone marrow mesenchymal stem cell
Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
... hBM-MSCs: Human bone marrow-derived mesenchymal stem cells; hBM- MSC-Ex: Human bone marrow mesenchymal stem cell-derived exosomes; ALP: ...
10
Where is the common ground between bone marrow mesenchymal stem/stromal cells from different donors and species?
... In cell therapy and tissue engineering communities, MSC isolation commonly implies the production of plastic adherent cultures starting from minimally processed BM aspirates or tissue digests ...both human ...
8
Culture and Growth Characterization of Human Mesenchymal Stem Cells from Dental Pulp
... of mesenchymal stem cells (MSCs, a term first coined by Arnold Caplan in 1991, can be traced to experiments demonstrating that transplantation of bone marrow (BM) to heterotopic anatomical ...
90
Original Article Comparison of different conditions for culturing of mesenchymal stem cells from human umbilical cord Wharton’s jelly
... Efficient and consistent lar- ge-scale expansion of all cells, including hUC-MSCs, is a limiting factor for cells used in cell-based therapy. The current study demon- strated that, under hypoxic and serum-free ...
16
Comparative analysis of curative effect of bone marrow mesenchymal stem cell and bone marrow mononuclear cell transplantation for spastic cerebral palsy
... of cell transplanta- tion were studied through animal experiment, and there are three major mechanisms: (1) regeneration and differ- entiation mechanism: the transplanted cells differentiate into corresponding ...
9
Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders
... of human MSCs to define their characteristics [5]: (1) the ability to adhere to plastic plates; (2) the ability to differentiate into osteoblasts, adipocytes, and chondroblasts in vitro; and (3) the positive ...
7
The challenges and promises of allogeneic mesenchymal stem cells for use as a cell-based therapy
... hematopoietic stem cell trans- plantation in preclinical [34] and clinical studies ...first stem cell drug, has been approved for the ...from bone marrow aspirates of healthy ...
7
A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
... needed. Stem cells may provide the basis for a new approach. Emerging stem cell therapy of brain tumors The lack of efficacy for conventional treatments of malig- nant brain tumors can be readily ...
11
Characterization and Therapeutic Application of Mesenchymal Stem Cells with Neuromesodermal Origin from Human Pluripotent Stem Cells
... Mesenchymal stem cells (MSC) hold great therapeutic potential for cell-based tissue engineering and regenerative medicine, as they offer the benefits of easy isolation, multipotency, paracrine ...
15
Abstract: Mesenchymal Stem Cells derived from bone marrow (hBM-MSCs) are utilized in tendon
... Jelly Mesenchymal Stem Cells (hWJ-MSCs) were isolated from female donors (mean age 28, unrelated to the male donors) who gave written informed consent in accordance with the Declaration of Helsinki to use ...
22
New perspectives in human stem cell therapeutic research
... Human stem cells are in evaluation in clinical stem cell trials, primarily as autologous bone marrow studies, autologous and allogenic mesenchymal stem cell ...
5
Schlicker, Andreas (2011): Einflussfaktoren auf die Proliferation und die neuronale Differenzierung humaner mesenchymaler Knochenmarkszellen. Dissertation, LMU München: Medizinische Fakultät
... “Neural cell differentiation in vitro from adult human bone marrow mesenchymal stem cells.” Stem Cells and Development 14 (1): 65-69.. “Stem cell transplantation as a therapeutic strate[r] ...
134
Large animal models for stem cell therapy
... in human patients, and retinitis pigmentosa [13], in which the anatomy of the pig eye is quite similar to that of the ...somatic cell nuclear transfer (SCNT), the same cloning technology employed to create ...
9
Stem cells in retinal regeneration: past, present and future
... AMD is a complex degenerative disease with a polygenic hereditary component (Haines et al., 2005; Churchill et al., 2006). It arises as the result of chronic, low grade inflammation in the central outer retina, which ...
10
Stem cell technology for bone regeneration: current status and potential applications
... involving bone. The ESC are a pluripotent stem cell population which, by definition, possess an unlimited potential to differentiate into all three germ tissue lineages: ectoderm; endoderm; and ...
10
Urine-derived stem cells for potential use in bladder repair
... modified stem cells via transfection of the VEGF gene significantly promoted myogenic differentiation of USCs and induced angiogenesis and innervation ...for stem cell therapy to increase ...
10
Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis
... Adipose-derived mesenchymal stem cell; ALD: Alcoholic liver disease; BM-MSC: Bone marrow-derived mesenchymal stem cell; CB-MSC: Cord blood- derived ...
7
Mesenchymal stem cell transplantation as an effective treatment strategy for ischemic stroke in Asia: a meta-analysis of controlled trials
... published literature is still not sufficient to perform reliable statistical analysis. Sources of MSC may also associate with treatment outcomes. Based on our extracted data, autogenous MSCs were associated with ...
20
Are mesenchymal stromal cells immune cells?
... the bone marrow, MSCs have a supportive function for the haematopoietic system and provide a niche for haematopoietic progenitor cells to ...the bone marrow and in other tissues, such as ...
7
Therapeutic prospects of extracellular vesicles in cancer treatment
... In addition to DCs, macrophages have also been studied as a source of EVs of potential therapeutic benefit. Derived from RAW 264.7 macrophages, vesicles loaded with PTX (exoPTX) were reported to significantly increase ...
10