Human foamy virus
The Roles of Pol and Env in the Assembly Pathway of Human Foamy Virus
... Human foamy virus (HFV) is the prototype of the Spuma- virus genus of the Retroviridae family ...a human cancer patient (1), but, based on homology with other primate isolates, it is ...
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Palindromic Sequence Plays a Critical Role in Human Foamy Virus Dimerization
... the foamy virus life cycle is quite divergent from that of other retroviruses (reviewed in reference ...on foamy virus sequences need nucle- otides in the pol open reading frame (ORF) in ...
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Expression and maturation of human foamy virus Gag precursor polypeptides.
... of human foamy virus previously reported to be ...free virus particles, two Gag precursor polypeptides were identified at approximately 72 and 68 kDa, p72 giving rise to p68 by a maturation ...
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Sequences in pol Are Required for Transfer of Human Foamy Virus-Based Vectors
... A series of vectors with heterologous genes was constructed from HSRV1, an infectious clone of human foamy virus (HFV), and transfected into baby hamster kidney cells to generate stably transfected ...
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Involvement of a spliced and defective human foamy virus in the establishment of chronic infection.
... a human foamy virus (HFV) genome or the early viral genes in transgenic mice leads to progressive myopathy and encephalopathy (4), raising ques- tions about this ...
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Productive persistent infection of hematopoietic cells by human foamy virus.
... Human foamy virus can establish persistent infections in human hematopoietic cell lines, such as ...the virus titer does not decrease during ...
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Molecular Characterization of Proteolytic Processing of the Pol Proteins of Human Foamy Virus Reveals Novel Features of the Viral Protease
... Human foamy virus (HFV) is the prototypic spumavirus that has distinct features of gene expression different from those of other known ...retroviruses. Foamy viruses (FVs) as complex ...
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The carboxyl terminus of the human foamy virus Gag protein contains separable nucleic acid binding and nuclear transport domains.
... of human foamy virus (HFV) lacks Cys-His boxes present in the nucleocapsid (NC) domains of other retroviruses; instead it contains three glycine-arginine-rich motifs (GR ...but virus ...
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Multiple Integrations of Human Foamy Virus in Persistently Infected Human Erythroleukemia Cells
... However, foamy virus replication also resembles that of hepadnaviruses in many ...of human foamy virus (HFV) ...A virus lacking the Gag nuclear localization signal accumulates ...
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In vitro infection of primary and retrovirus-infected human leukocytes by human foamy virus.
... of human foamy virus (HFV) was examined in primary and cultured human ...the human kidney cell line 293 transfected with an infectious molecular clone of ...of human myeloid and ...
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Evidence that the Human Foamy Virus Genome Is DNA
... Human foamy virus (HFV) is the prototype virus of the Spumavirus genus of ...a human virus because the first isolation was from a human cancer-derived cell line (1); ...
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Relationship of the env genes and the endonuclease domain of the pol genes of simian foamy virus type 1 and human foamy virus.
... Relatedness of human foamy virus and simian foamy virus type 1 Amino acid sequences Conserved Similar % Similarity' pol gene endonuclease External Transmembrane env domain env domain 73 [r] ...
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Human foamy virus Bel1 transactivator contains a bipartite nuclear localization determinant which is sensitive to protein context and triple multimerization domains.
... of human foamy virus is a 300-amino-acid nuclear regulatory protein which transactivates the gene expression directed by the homologous long terminal repeat and the human immunodeficiency ...
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Efficient pseudotyping of murine leukemia virus particles with chimeric human foamy virus envelope proteins.
... chimeric human immunodeficiency virus (HIV) envelope proteins containing a 26-aa cytoplasmic do- main of the VSV-G protein (23), where the position of the VSV-G cytoplasmic domain was crucial for particle ...
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Functional analysis of human foamy virus accessory reading frames.
... Since only the bel-1 protein has been assigned a function, we aimed to investigate the relevance of the accessory HEV reading frames for the viral replication cycle by analyzing single b[r] ...
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Endonucleolytic cleavages and DNA-joining activities of the integration protein of human foamy virus.
... An oligonucleotide with a random sequence that was completely different from the wild-type sequence did not function as a substrate for the endonuclease of the recombinant HFV IN protein[r] ...
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Functional organization of the Bel-1 trans activator of human foamy virus.
... The hypothesis that Bel-1 sequences proximal to the C terminus include a discrete activation domain has now been further validated by our recent observation that a fusion protein derived[r] ...
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Human foamy virus polypeptides: identification of env and bel gene products.
... Viral proteins were immunoprecipitated with polyclonal rabbit antisera raised against whole virus lanes 1, 2, and 5, against bell lanes 3 and 6, and against bel2 lane 4 and also with two[r] ...
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Human foamy virus reverse transcription that occurs late in the viral replication cycle.
... of virus-infected cells was determined via staining for b -galactosidase ...45 virus DNA copies per infected ...500 virus DNA copies per infected cell was calculated (80% infected cells on day ...
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Further Characterization of Equine Foamy Virus Reveals Unusual Features among the Foamy Viruses
... equine foamy virus (EFV) was isolated from healthy horses and was characterized by molecular cloning and nucleotide sequence ...the human foamy virus (HFV), the prototype of FVs, a ...
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