Hydrotropic solubilization technique
Preparation of solid dispersions of ornidazole using mixed hydrotropic solubilization technique and their characterization
... mixed hydrotropic solubilization ...water-soluble hydrotropic carriers show the fast release of drug as compared with the pure bulk drug sample and PM; the quick onset of action and better extent of ...
6
FORMULATION, OPTIMIZATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF PIROXICAM USING HYDROTROPIC SOLUBILIZATION TECHNIQUE
... using hydrotropic solubilization technique and develop its mouth dissolving tablets which resulted in enhanced solubility and thus bioavailability of the ...and hydrotropic solid dispersions ...
8
HYDROTROPIC SOLUBILIZATION TECHNIQUE TO CHALLENGE THE SOLUBILITY OF POORLY WATER SOLUBLE DRUG VALSARTAN
... effects. Hydrotropic solubilization is one of the enhancement techniques which enhance solubility of drug to many folds with the use of hydrotropes like sodium acetate, sodium benzoate, sodium citrate, urea ...
13
NOVEL APPLICATION OF MIXED HYDROTROPIC SOLUBILIZATION TECHNIQUE IN THE FORMULATION AND EVALUATION OF SOLID DISPERSION OF FLUPIRTINE MALEATE
... The solid dispersions of flupirtine maleate were developed using the concept of mixed hydrotropic solubilization technique. Solid dispersions containing blend of niacinamide and sodium benzoate as ...
8
UV-SPECTROPHOTOMETRIC DETERMINATION OF METRONIDAZOLE IN BULK AND PHARMACEUTICAL DOSAGE FORM USING HYDROTROPIC SOLUBILIZATION TECHNIQUE
... On the other hand, planarity of the hydrophobic part has been emphasized as an important factor in the mechanism of hydrotropic solubilization. Hydrotropes commonly used includes sodium benzoate, sodium ...
7
NOVEL AND VALIDATED SPECTROPHOTOMETRIC DETERMINATION OF BUDESONIDE FROM BULK AND TABLETS USING MIXED HYDROTROPIC SOLUBILIZATION TECHNIQUE
... as hydrotropic solubilizing agent for the quantitative determination of poorly water-soluble budesonide from bulk and tablet dosage ...mixed hydrotropic solution as compared to solubility in distilled ...
5
FORMULATION DEVELOPMENT OF AQUEOUS INJECTION OF POORLY SOLUBLE DRUG USING MIXED HYDROTROPIC SOLUBILIZATION CONCEPT AND ITS EVALUATION
... of hydrotropic agents giving synergistic solvent action can minimize the amount of hydrotropic agents employed, minimizing the chances of their individual ...mixed hydrotropic solubilization ...
5
SPECTROPHOTOMETRIC QUANTIFICATION OF ETORICOXIB IN BULK DRUG AND TABLETS USING HYDROTROPIC AGENT
... Hydrotropic solubilization technique is used to increase aqueous solubilities of poorly water soluble drugs using hydrotropic ...investigation hydrotropic solution of sodium benzoate ...
7
Hydrotropic Aggregation Behavior of Butyl Stearate
... Sod.salicylate 4.985 5.6911 7.684 9.929 The knowledge of MHC and cmax values of each hydrotrope with respect to a particular solute assumes greater significance in this study since it indicates the beginning and ...
7
Hydrotropic Solubilization
... employed hydrotropic solubilization technique to solubilize the poorly water-soluble NSAID, ...sodium hydrotropic solution and distilled water was carried out at ...(inexpensive ...
7
FORMULATION DEVELOPMENT AND EVALUATION OF HYDROTROPIC SOLUBILIZATION BASED SUSPENSIONS OF ITRACONAZOLEAmareshwar Shabada*, Yellanki Prashanthi,CH. Yella Reddy, Boya VivekanandaDOWNLOAD/VIEW
... the technique of hydrotropic solubilization technique and convert them into suitable oral liquid dosage form (suspension) useful for enhancement of ...minutes. Hydrotropic ...
10
FORMULATION AND CHARACTERIZATION OF FAST DISINTEGRATING TABLET OF GLICLAZIDE BY HYDROTROPY TECHNIQUE
... Hydrotropic Solubilization technique is useful for improving the dissolution of poorly water soluble drugs by overcoming crystal lattice energy, as it concomitantly decreases the size of medicament ...
6
HYDROTROPHY: NOVEL SOLUBILITY ENHANCEMENT TECHNIQUE: A REVIEW
... enhancement technique is the key to ensure the good formulation like good oral bioavailability, reduced dosing frequency, better patient compliance and low cost of production and all these features can be achieved ...
12
HYDROTROPIC SOLUBILIZATION: A PROMISING TECHNIQUE TO ENHANCE SOLUBILITY OF POORLY WATER SOLUBLE DRUG LUMEFANTRINE
... those, hydrotropic solubilization is one of the solubility enhancement techniques applicable to enhance solubility of hydrophobic drugs with the use of hydrotropes like sodium benzoate, urea, piperazine ...
7
New analytical method for the quantitative analysis of ornidazole in bulk as well as various dosage forms by hydrotropic solubilisation technique
... A thorough literature survey of the various analytical methods for the quantitative estimation of Ornidazole in both bulk drug and dosage forms has revealed that very few analytical methods are available utilizing the ...
8
FORMULATION AND EVALUATION OF SULPHASALAZINE INJECTION MADE BY MIXED SOLVENCY SOLUBILIZATION TECHNIQUE
... 2. Preparation of aqueous solution of sulphasalazine For the preparation of aqueous solution of sulphasalazine, about 35 ml of hydrotropic blends solution was taken in 50 ml of volumetric flask. Weighed amount of ...
7
Enhanced Solubility of Modafinil via Solubilization Techniques
... compare solubilization approaches, namely cosolvency, micelle solubilization, complexation, pH adjustment and hydrotrophy, on BCS class II drug modafinil ...of solubilization is depicted to enhance ...
6
Effect of Soya Lecithin on Solubilization and Biodegradation of Pentachlorophenol by Anthracophyllum discolor
... on solubilization and biodegradation of pentachlorophenol (PCP) by Anthraco- phyllum discolor was ...PCP solubilization test was performed for 100, 200 and 400 mg ∙L −1 with SL solution varying ...
11
Crystallization of Curcumin and Cinnamic Acid from Aqueous Solutions of Hydrotropes
... The hydrotropic solubilization of cinnamic acid, aspartic acid, curcumin, thymol, and benzocaine as a function of temperature, using sodium cinnamate (Na-CIN) as photosensitive hydro- trope, has been ...
15
FORMULATION AND EVALUATION OF HYDROTROPIC SOLID DISPERSION OF ELUXADOLINE
... The formulation of hydrotropic solid dispersion of Eluxadoline with different ratio sodium caprylate screened for the selection of suitable ratios. Above all the formulations, the ratio of Eluxadoline: Sodium ...
5